Joel N. Meyer Nicholas School of the Environment Duke University Biography Publications Institution JoVE Articles Joel N. Meyer has not added a biography. If you are Joel N. Meyer and would like to personalize this page please email our Author Liaison for assistance. Publications Mitochondrial DNA Mutagenesis: Feature of and Biomarker for Environmental Exposures and Aging Current Environmental Health Reports. Nov, 2021 | Pubmed ID: 34761353 Calcium/Calmodulin Dependent Protein Kinase Kinase 2 Regulates the Expansion of Tumor-Induced Myeloid-Derived Suppressor Cells Frontiers in Immunology. 2021 | Pubmed ID: 34712241 Direct Comparisons of Bisulfite Pyrosequencing Versus Targeted Bisulfite Sequencing MicroPublication Biology. 2021 | Pubmed ID: 34423283 Lack of Detectable Direct Effects of Silver and Silver Nanoparticles on Mitochondria in Mouse Hepatocytes Environmental Science & Technology. Aug, 2021 | Pubmed ID: 34346225 PCR-Based Determination of Mitochondrial DNA Copy Number in Multiple Species Methods in Molecular Biology (Clifton, N.J.). 2021 | Pubmed ID: 34096001 Early-life Mitochondrial DNA Damage Results in Lifelong Deficits in Energy Production Mediated by Redox Signaling in Caenorhabditis Elegans Redox Biology. 07, 2021 | Pubmed ID: 33993056 Xenobiotic Metabolism and Transport in Journal of Toxicology and Environmental Health. Part B, Critical Reviews. Feb, 2021 | Pubmed ID: 33616007 Multiple Metabolic Changes Mediate the Response of Caenorhabditis Elegans to the Complex I Inhibitor Rotenone Toxicology. 01, 2021 | Pubmed ID: 33188857 Evaluation of Peruvian Government Interventions to Reduce Childhood Anemia Annals of Global Health. 08, 2020 | Pubmed ID: 32864350 Risuteganib Protects Against Hydroquinone-induced Injury in Human RPE Cells Investigative Ophthalmology & Visual Science. 08, 2020 | Pubmed ID: 32818234 Zebrafish CYP1A Expression in Transgenic Caenorhabditis Elegans Protects from Exposures to Benzo[a]pyrene and a Complex Polycyclic Aromatic Hydrocarbon Mixture Toxicology. 07, 2020 | Pubmed ID: 32360973 Resveratrol Protects Against Hydroquinone-Induced Oxidative Threat in Retinal Pigment Epithelial Cells Investigative Ophthalmology & Visual Science. 04, 2020 | Pubmed ID: 32334435 Fluorescence-based Sorting of Caenorhabditis Elegans Via Acoustofluidics Lab on a Chip. 05, 2020 | Pubmed ID: 32292982 Effects of Immunosuppressive Medications on Mitochondrial Function The Journal of Surgical Research. 05, 2020 | Pubmed ID: 31918330 Caveats to the Use of MTT, Neutral Red, Hoechst and Resazurin to Measure Silver Nanoparticle Cytotoxicity Chemico-biological Interactions. Jan, 2020 | Pubmed ID: 31669321 Strain Sensitivity to Sodium Arsenite Exposure is Varied Based on Age and Outcome Measured MicroPublication Biology. Oct, 2019 | Pubmed ID: 32550437 Swim Exercise in Extends Neuromuscular and Gut Healthspan, Enhances Learning Ability, and Protects Against Neurodegeneration Proceedings of the National Academy of Sciences of the United States of America. 11, 2019 | Pubmed ID: 31685639 Mitochondrial Bioenergetic Changes During Development As an Indicator of Health-span Aging. 08, 2019 | Pubmed ID: 31454791 Strengths and Limitations of Morphological and Behavioral Analyses in Detecting Dopaminergic Deficiency in Caenorhabditis Elegans Neurotoxicology. 09, 2019 | Pubmed ID: 31323240 Mitochondria As a Target of Organophosphate and Carbamate Pesticides: Revisiting Common Mechanisms of Action with New Approach Methodologies Reproductive Toxicology (Elmsford, N.Y.). 10, 2019 | Pubmed ID: 31315019 Genetic Defects in Mitochondrial Dynamics in Impact Ultraviolet C Radiation- and 6-hydroxydopamine-Induced Neurodegeneration International Journal of Molecular Sciences. Jun, 2019 | Pubmed ID: 31261893 Open Source Acoustofluidics Lab on a Chip. 07, 2019 | Pubmed ID: 31240285 MANF Deletion Abrogates Early Larval Caenorhabditis Elegans Stress Response to Tunicamycin and Pseudomonas Aeruginosa European Journal of Cell Biology. Dec, 2019 | Pubmed ID: 31138438 Linking Mitochondrial Dysfunction to Organismal and Population Health in the Context of Environmental Pollutants: Progress and Considerations for Mitochondrial Adverse Outcome Pathways Environmental Toxicology and Chemistry. 08, 2019 | Pubmed ID: 31034624 Surface Acoustic Waves Enable Rotational Manipulation of Caenorhabditis Elegans Lab on a Chip. 03, 2019 | Pubmed ID: 30768117 Predictors of Mitochondrial DNA Copy Number and Damage in a Mercury-exposed Rural Peruvian Population Near Artisanal and Small-scale Gold Mining: An Exploratory Study Environmental and Molecular Mutagenesis. 03, 2019 | Pubmed ID: 30289587 Blinded Visual Scoring of Images Using the Freely-available Software Blinder Bio-protocol. Dec, 2018 | Pubmed ID: 30761327 Nonselective Autophagy Reduces Mitochondrial Content During Starvation in Caenorhabditis Elegans American Journal of Physiology. Cell Physiology. 12, 2018 | Pubmed ID: 30133321 Caenorhabditis Elegans As an Emerging Model System in Environmental Epigenetics Environmental and Molecular Mutagenesis. 08, 2018 | Pubmed ID: 30091255 Newly Revised Quantitative PCR-Based Assay for Mitochondrial and Nuclear DNA Damage Current Protocols in Toxicology. 05, 2018 | Pubmed ID: 30040241 Swimming Exercise and Transient Food Deprivation in Caenorhabditis Elegans Promote Mitochondrial Maintenance and Protect Against Chemical-Induced Mitotoxicity Scientific Reports. 05, 2018 | Pubmed ID: 29844465 Mitochondrial Toxicity Toxicological Sciences : an Official Journal of the Society of Toxicology. 03, 2018 | Pubmed ID: 29340618 The High-production Volume Fungicide Pyraclostrobin Induces Triglyceride Accumulation Associated with Mitochondrial Dysfunction, and Promotes Adipocyte Differentiation Independent of PPARγ Activation, in 3T3-L1 Cells Toxicology. 01, 2018 | Pubmed ID: 29127035 Materials and Toxicological Approaches to Study Metal and Metal-oxide Nanoparticles in the Model Organism Materials Horizons. Sep, 2017 | Pubmed ID: 29057078 Toxicological Implications of Mitochondrial Localization of CYP2E1 Toxicology Research. 2017 | Pubmed ID: 28989700 Role of Mitochondrial DNA Damage and Dysfunction in Veterans with Gulf War Illness PloS One. 2017 | Pubmed ID: 28910366 Mitochondrial Fusion, Fission, and Mitochondrial Toxicity Toxicology. 11, 2017 | Pubmed ID: 28789970 Zebrafish Have an Ethanol-inducible Hepatic 4-nitrophenol Hydroxylase That is Not CYP2E1-like Environmental Toxicology and Pharmacology. Sep, 2017 | Pubmed ID: 28728133 Sources, Mechanisms, and Consequences of Chemical-induced Mitochondrial Toxicity Toxicology. 11, 2017 | Pubmed ID: 28627407 Deficiencies in Mitochondrial Dynamics Sensitize Caenorhabditis Elegans to Arsenite and Other Mitochondrial Toxicants by Reducing Mitochondrial Adaptability Toxicology. 07, 2017 | Pubmed ID: 28602540 Exposure to Polycyclic Aromatic Hydrocarbons and Volatile Organic Compounds Among Recently Pregnant Rural Guatemalan Women Cooking and Heating with Solid Fuels International Journal of Hygiene and Environmental Health. 06, 2017 | Pubmed ID: 28320639 Effects of Methyl and Inorganic Mercury Exposure on Genome Homeostasis and Mitochondrial Function in Caenorhabditis Elegans DNA Repair. 04, 2017 | Pubmed ID: 28242054 Biogas Stoves Reduce Firewood Use, Household Air Pollution, and Hospital Visits in Odisha, India Environmental Science & Technology. 01, 2017 | Pubmed ID: 27785914 Effects of Reduced Mitochondrial DNA Content on Secondary Mitochondrial Toxicant Exposure in Caenorhabditis Elegans Mitochondrion. 09, 2016 | Pubmed ID: 27566481 In Vivo Determination of Mitochondrial Function Using Luciferase-Expressing Caenorhabditis Elegans: Contribution of Oxidative Phosphorylation, Glycolysis, and Fatty Acid Oxidation to Toxicant-Induced Dysfunction Current Protocols in Toxicology. 08, 2016 | Pubmed ID: 27479364 Distinctive Adaptive Response to Repeated Exposure to Hydrogen Peroxide Associated with Upregulation of DNA Repair Genes and Cell Cycle Arrest Redox Biology. 10, 2016 | Pubmed ID: 27479053 From the Cover: Arsenite Uncouples Mitochondrial Respiration and Induces a Warburg-like Effect in Caenorhabditis Elegans Toxicological Sciences : an Official Journal of the Society of Toxicology. 08, 2016 | Pubmed ID: 27208080 Antagonistic Growth Effects of Mercury and Selenium in Caenorhabditis Elegans Are Chemical-Species-Dependent and Do Not Depend on Internal Hg/Se Ratios Environmental Science & Technology. Mar, 2016 | Pubmed ID: 26938845 PCR-Based Analysis of Mitochondrial DNA Copy Number, Mitochondrial DNA Damage, and Nuclear DNA Damage Current Protocols in Toxicology. Feb, 2016 | Pubmed ID: 26828332 Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd Edition) Autophagy. Jan, 2016 | Pubmed ID: 26799652 Mitochondrial DNA Damage Induced Autophagy, Cell Death, and Disease Frontiers in Bioscience (Landmark Edition). Jan, 2016 | Pubmed ID: 26709760 Intracellular Trafficking Pathways in Silver Nanoparticle Uptake and Toxicity in Caenorhabditis Elegans Nanotoxicology. 09, 2016 | Pubmed ID: 26559224 Seahorse Xfe 24 Extracellular Flux Analyzer-Based Analysis of Cellular Respiration in Caenorhabditis Elegans Current Protocols in Toxicology. Nov, 2015 | Pubmed ID: 26523474 Caenorhabditis Elegans As a Model for Toxic Effects of Nanoparticles: Lethality, Growth, and Reproduction Current Protocols in Toxicology. Nov, 2015 | Pubmed ID: 26523472 Reducing Environmental Toxicity of Silver Nanoparticles Through Shape Control Environmental Science & Technology. Aug, 2015 | Pubmed ID: 26146787 Mitochondrial Morphology and Fundamental Parameters of the Mitochondrial Respiratory Chain Are Altered in Caenorhabditis Elegans Strains Deficient in Mitochondrial Dynamics and Homeostasis Processes PloS One. 2015 | Pubmed ID: 26106885 AHR2-Mediated Transcriptomic Responses Underlying the Synergistic Cardiac Developmental Toxicity of PAHs Toxicological Sciences : an Official Journal of the Society of Toxicology. Feb, 2015 | Pubmed ID: 25412620 Silver Nanoparticle Toxicity to Atlantic Killifish (Fundulus Heteroclitus) and Caenorhabditis Elegans: a Comparison of Mesocosm, Microcosm, and Conventional Laboratory Studies Environmental Toxicology and Chemistry. Feb, 2015 | Pubmed ID: 25393776 PCR Based Determination of Mitochondrial DNA Copy Number in Multiple Species Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 25308485 Exposure to Mitochondrial Genotoxins and Dopaminergic Neurodegeneration in Caenorhabditis Elegans PloS One. 2014 | Pubmed ID: 25486066 Mitochondria, Energetics, Epigenetics, and Cellular Responses to Stress Environmental Health Perspectives. Dec, 2014 | Pubmed ID: 25127496 DEPDC1/LET-99 Participates in an Evolutionarily Conserved Pathway for Anti-tubulin Drug-induced Apoptosis Nature Cell Biology. Aug, 2014 | Pubmed ID: 25064737 Developmental Toxicity and DNA Damage from Exposure to Parking Lot Runoff Retention Pond Samples in the Japanese Medaka (Oryzias Latipes) Marine Environmental Research. Aug, 2014 | Pubmed ID: 24816191 Comparative Toxicity of Silver Nanoparticles on Oxidative Stress and DNA Damage in the Nematode, Caenorhabditis Elegans Chemosphere. Aug, 2014 | Pubmed ID: 24726479 Effects of 5'-fluoro-2-deoxyuridine on Mitochondrial Biology in Caenorhabditis Elegans Experimental Gerontology. Aug, 2014 | Pubmed ID: 24704715 Silver Nanoparticle Behavior, Uptake, and Toxicity in Caenorhabditis Elegans: Effects of Natural Organic Matter Environmental Science & Technology. Mar, 2014 | Pubmed ID: 24568198 The Tobacco-specific Nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) Induces Mitochondrial and Nuclear DNA Damage in Caenorhabditis Elegans Environmental and Molecular Mutagenesis. Jan, 2014 | Pubmed ID: 24014178 Sulfidation of Silver Nanoparticles: Natural Antidote to Their Toxicity Environmental Science & Technology. Nov, 2013 | Pubmed ID: 24180218 Assessing Different Mechanisms of Toxicity in Mountaintop Removal/valley Fill Coal Mining-affected Watershed Samples Using Caenorhabditis Elegans PloS One. 2013 | Pubmed ID: 24066176 Effects of Mutations in Mitochondrial Dynamics-related Genes on the Mitochondrial Response to Ultraviolet C Radiation in Developing Caenorhabditis Elegans Worm. Jan, 2013 | Pubmed ID: 24058863 Mitochondria As a Target of Environmental Toxicants Toxicological Sciences : an Official Journal of the Society of Toxicology. May, 2013 | Pubmed ID: 23629515 A Call for Fuller Reporting of Toxicity Test Data Integrated Environmental Assessment and Management. Apr, 2013 | Pubmed ID: 23529809 Effects of Early Life Exposure to Ultraviolet C Radiation on Mitochondrial DNA Content, Transcription, ATP Production, and Oxygen Consumption in Developing Caenorhabditis Elegans BMC Pharmacology & Toxicology. Feb, 2013 | Pubmed ID: 23374645 UVC-induced Mitochondrial Degradation Via Autophagy Correlates with MtDNA Damage Removal in Primary Human Fibroblasts Journal of Biochemical and Molecular Toxicology. Jan, 2013 | Pubmed ID: 23132756 In Vivo Repair of Alkylating and Oxidative DNA Damage in the Mitochondrial and Nuclear Genomes of Wild-type and Glycosylase-deficient Caenorhabditis Elegans DNA Repair. Nov, 2012 | Pubmed ID: 22959841 Analysis of DNA Damage and Repair in Nuclear and Mitochondrial DNA of Animal Cells Using Quantitative PCR Methods in Molecular Biology (Clifton, N.J.). 2012 | Pubmed ID: 22941600 Involvement of Autophagy and Mitochondrial Dynamics in Determining the Fate and Effects of Irreparable Mitochondrial DNA Damage Autophagy. Dec, 2012 | Pubmed ID: 22929123 Mitochondrial DNA-depleted A549 Cells Are Resistant to Bleomycin American Journal of Physiology. Lung Cellular and Molecular Physiology. Sep, 2012 | Pubmed ID: 22773697 Mitochondrial Dynamics and Autophagy Aid in Removal of Persistent Mitochondrial DNA Damage in Caenorhabditis Elegans Nucleic Acids Research. Sep, 2012 | Pubmed ID: 22718972 Human Mitochondrial DNA Polymerase γ Exhibits Potential for Bypass and Mutagenesis at UV-induced Cyclobutane Thymine Dimers The Journal of Biological Chemistry. Mar, 2012 | Pubmed ID: 22194617 Mechanism of Silver Nanoparticle Toxicity is Dependent on Dissolved Silver and Surface Coating in Caenorhabditis Elegans Environmental Science & Technology. Jan, 2012 | Pubmed ID: 22148238 Caenorhabditis Elegans Generates Biologically Relevant Levels of Genotoxic Metabolites from Aflatoxin B1 but Not Benzo[a]pyrene in Vivo Toxicological Sciences : an Official Journal of the Society of Toxicology. Dec, 2010 | Pubmed ID: 20864627 Intracellular Uptake and Associated Toxicity of Silver Nanoparticles in Caenorhabditis Elegans Aquatic Toxicology (Amsterdam, Netherlands). Oct, 2010 | Pubmed ID: 20708279 Comparative Biological Effects and Potency of 17α- and 17β-estradiol in Fathead Minnows Aquatic Toxicology (Amsterdam, Netherlands). Oct, 2010 | Pubmed ID: 20692052 Dynamic Zebrafish Interactome Reveals Transcriptional Mechanisms of Dioxin Toxicity PloS One. May, 2010 | Pubmed ID: 20463971 The QPCR Assay for Analysis of Mitochondrial DNA Damage, Repair, and Relative Copy Number Methods (San Diego, Calif.). Aug, 2010 | Pubmed ID: 20123023 Altered Gene Expression and DNA Damage in Peripheral Blood Cells from Friedreich's Ataxia Patients: Cellular Model of Pathology PLoS Genetics. Jan, 2010 | Pubmed ID: 20090835 QPCR: a Tool for Analysis of Mitochondrial and Nuclear DNA Damage in Ecotoxicology Ecotoxicology (London, England). Apr, 2010 | Pubmed ID: 20049526 Nucleotide Excision Repair Genes Are Expressed at Low Levels and Are Not Detectably Inducible in Caenorhabditis Elegans Somatic Tissues, but Their Function is Required for Normal Adult Life After UVC Exposure Mutation Research. Jan, 2010 | Pubmed ID: 19879883 UV Disinfection of Adenoviruses: Molecular Indications of DNA Damage Efficiency Applied and Environmental Microbiology. Jan, 2009 | Pubmed ID: 18978087 The Long Amplicon Quantitative PCR for DNA Damage Assay As a Sensitive Method of Assessing DNA Damage in the Environmental Model, Atlantic Killifish (Fundulus Heteroclitus) Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP. Mar, 2009 | Pubmed ID: 18706522 Caenorhabditis Elegans: an Emerging Model in Biomedical and Environmental Toxicology Toxicological Sciences : an Official Journal of the Society of Toxicology. Nov, 2008 | Pubmed ID: 18566021 Nonadditive Effects of PAHs on Early Vertebrate Development: Mechanisms and Implications for Risk Assessment Toxicological Sciences : an Official Journal of the Society of Toxicology. Sep, 2008 | Pubmed ID: 18156145 Fundulus As the Premier Teleost Model in Environmental Biology: Opportunities for New Insights Using Genomics Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics. Dec, 2007 | Pubmed ID: 18071578 Analysis of CpG Methylation in the Killifish CYP1A Promoter Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP. Aug, 2005 | Pubmed ID: 16257583 Differential Display of Hepatic MRNA from Killifish (Fundulus Heteroclitus) Inhabiting a Superfund Estuary Aquatic Toxicology (Amsterdam, Netherlands). Jul, 2005 | Pubmed ID: 15916819 Antioxidant Defenses in Killifish (Fundulus Heteroclitus) Exposed to Contaminated Sediments and Model Prooxidants: Short-term and Heritable Responses Aquatic Toxicology (Amsterdam, Netherlands). Dec, 2003 | Pubmed ID: 14568353 Expression and Inducibility of Aryl Hydrocarbon Receptor Pathway Genes in Wild-caught Killifish (Fundulus Heteroclitus) with Different Contaminant-exposure Histories Environmental Toxicology and Chemistry. Oct, 2003 | Pubmed ID: 14551997 Cytochrome P4501A (CYP1A) in Killifish (Fundulus Heteroclitus): Heritability of Altered Expression and Relationship to Survival in Contaminated Sediments Toxicological Sciences : an Official Journal of the Society of Toxicology. Jul, 2002 | Pubmed ID: 12075112 Quantifying Levels of Dopaminergic Neuron Morphological Alteration and Degeneration in Caenorhabditis elegans Shefali R. Bijwadia1, Katherine Morton1, Joel N. Meyer1 1Nicholas School of the Environment, Duke University JoVE 62894 Neurociência
Quantifying Levels of Dopaminergic Neuron Morphological Alteration and Degeneration in Caenorhabditis elegans Shefali R. Bijwadia1, Katherine Morton1, Joel N. Meyer1 1Nicholas School of the Environment, Duke University JoVE 62894 Neurociência