Karen Ocorr Development and Aging Program, NASCR Center The Sanford Burnham Institute for Medical Research Biography Publications Institution JoVE Articles Karen Ocorr has not added a biography. If you are Karen Ocorr and would like to personalize this page please email our Author Liaison for assistance. Publications BIN1 is Reduced and Cav1.2 Trafficking is Impaired in Human Failing Cardiomyocytes Heart Rhythm : the Official Journal of the Heart Rhythm Society. Dec, 2011 | Pubmed ID: 22138472 Over-expression of DSCAM and COL6A2 Cooperatively Generates Congenital Heart Defects PLoS Genetics. Nov, 2011 | Pubmed ID: 22072978 The UNC-45 Chaperone is Critical for Establishing Myosin-based Myofibrillar Organization and Cardiac Contractility in the Drosophila Heart Model PloS One. 2011 | Pubmed ID: 21799905 ATP-sensitive Potassium Channel (K(ATP))-dependent Regulation of Cardiotropic Viral Infections Proceedings of the National Academy of Sciences of the United States of America. Jul, 2011 | Pubmed ID: 21719711 Tinman/Nkx2-5 Acts Via MiR-1 and Upstream of Cdc42 to Regulate Heart Function Across Species The Journal of Cell Biology. Jun, 2011 | Pubmed ID: 21690310 Cloning and Characterization of the Cardiac-specific Lrrc10 Promoter BMB Reports. Feb, 2011 | Pubmed ID: 21345312 Phospholipid Homeostasis Regulates Lipid Metabolism and Cardiac Function Through SREBP Signaling in Drosophila Genes & Development. Jan, 2011 | Pubmed ID: 21245170 Drosophila As a Model to Study Cardiac Aging Experimental Gerontology. May, 2011 | Pubmed ID: 21130861 The Effect of Excess Expression of GFP in a Novel Heart-specific Green Fluorescence Zebrafish Regulated by Nppa Enhancer at Early Embryonic Development Molecular Biology Reports. Feb, 2011 | Pubmed ID: 20383585 High-fat-diet-induced Obesity and Heart Dysfunction Are Regulated by the TOR Pathway in Drosophila Cell Metabolism. Nov, 2010 | Pubmed ID: 21035763 SAMD4B, a Novel SAM-containing Protein, Inhibits AP-1-, P53- and P21-mediated Transcriptional Activity BMB Reports. May, 2010 | Pubmed ID: 20510020 A Global in Vivo Drosophila RNAi Screen Identifies NOT3 As a Conserved Regulator of Heart Function Cell. Apr, 2010 | Pubmed ID: 20371351 Sestrin As a Feedback Inhibitor of TOR That Prevents Age-related Pathologies Science (New York, N.Y.). Mar, 2010 | Pubmed ID: 20203043 KBTBD7, a Novel Human BTB-kelch Protein, Activates Transcriptional Activities of SRE and AP-1 BMB Reports. Jan, 2010 | Pubmed ID: 20132730 Drug Discovery Through Functional Screening in the Drosophila Heart Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19718521 Heterozygous Mutation of Drosophila Opa1 Causes the Development of Multiple Organ Abnormalities in an Age-dependent and Organ-specific Manner PloS One. 2009 | Pubmed ID: 19718456 D4eBP Acts Downstream of Both DTOR and DFoxo to Modulate Cardiac Functional Aging in Drosophila Aging Cell. Sep, 2009 | Pubmed ID: 19594484 A New Method for Detection and Quantification of Heartbeat Parameters in Drosophila, Zebrafish, and Embryonic Mouse Hearts BioTechniques. Feb, 2009 | Pubmed ID: 19317655 Non-autonomous Modulation of Heart Rhythm, Contractility and Morphology in Adult Fruit Flies Developmental Biology. Apr, 2009 | Pubmed ID: 19233157 Transcription Factor Neuromancer/TBX20 is Required for Cardiac Function in Drosophila with Implications for Human Heart Disease Proceedings of the National Academy of Sciences of the United States of America. Dec, 2008 | Pubmed ID: 19074289 A Novel Human BTB-kelch Protein KLHL31, Strongly Expressed in Muscle and Heart, Inhibits Transcriptional Activities of TRE and SRE Molecules and Cells. Nov, 2008 | Pubmed ID: 18719355 Dystrophin Deficiency in Drosophila Reduces Lifespan and Causes a Dilated Cardiomyopathy Phenotype Aging Cell. Mar, 2008 | Pubmed ID: 18221418 ZNF418, a Novel Human KRAB/C2H2 Zinc Finger Protein, Suppresses MAPK Signaling Pathway Molecular and Cellular Biochemistry. Mar, 2008 | Pubmed ID: 18084723 The Drosophila Muscle LIM Protein, Mlp84B, is Essential for Cardiac Function The Journal of Experimental Biology. Jan, 2008 | Pubmed ID: 18083727 Drosophila Aging 2006/2007 Experimental Gerontology. Jan, 2008 | Pubmed ID: 18061385 Myosin Transducer Mutations Differentially Affect Motor Function, Myofibril Structure, and the Performance of Skeletal and Cardiac Muscles Molecular Biology of the Cell. Feb, 2008 | Pubmed ID: 18045988 ZNF307, a Novel Zinc Finger Gene Suppresses P53 and P21 Pathway Biochemical and Biophysical Research Communications. Nov, 2007 | Pubmed ID: 17910948 Genetic Variation for Cardiac Dysfunction in Drosophila PloS One. 2007 | Pubmed ID: 17622346 Genetic Control of Heart Function and Aging in Drosophila Trends in Cardiovascular Medicine. Jul, 2007 | Pubmed ID: 17574126 KCNQ Potassium Channel Mutations Cause Cardiac Arrhythmias in Drosophila That Mimic the Effects of Aging Proceedings of the National Academy of Sciences of the United States of America. Mar, 2007 | Pubmed ID: 17360457 Age-related Cardiac Disease Model of Drosophila Mechanisms of Ageing and Development. Jan, 2007 | Pubmed ID: 17125816 The ATP-sensitive Potassium (KATP) Channel-encoded DSUR Gene is Required for Drosophila Heart Function and is Regulated by Tinman Proceedings of the National Academy of Sciences of the United States of America. Aug, 2006 | Pubmed ID: 16882722 Fluorescent Labeling of Drosophila Heart Structures Nakissa N. Alayari1,2, Georg Vogler2, Ouarda Taghli-Lamallem2, Karen Ocorr2, Rolf Bodmer2, Anthony Cammarato1,2 1Biology Department, San Diego State University, 2Development and Aging Program, NASCR Center, The Sanford Burnham Institute for Medical Research JoVE 1423 Biologia Visualizing the Beating Heart in Drosophila Georg Vogler1, Karen Ocorr1 1Development and Aging Program, The Sanford Burnham Institute for Medical Research JoVE 1425 Biologia Semi-automated Optical Heartbeat Analysis of Small Hearts Karen Ocorr1, Martin Fink2, Anthony Cammarato1,3, Sanford I. Bernstein3, Rolf Bodmer1 1Development and Aging Program, The Sanford Burnham Institute for Medical Research, 2Cardiac Electrophysiology Group, Dept. of Physiology, Anatomy and Genetics, The Sanford Burnham Institute for Medical Research, 3Biology Department and Heart Institute, San Diego State University JoVE 1435 Biologia
Fluorescent Labeling of Drosophila Heart Structures Nakissa N. Alayari1,2, Georg Vogler2, Ouarda Taghli-Lamallem2, Karen Ocorr2, Rolf Bodmer2, Anthony Cammarato1,2 1Biology Department, San Diego State University, 2Development and Aging Program, NASCR Center, The Sanford Burnham Institute for Medical Research JoVE 1423 Biologia
Visualizing the Beating Heart in Drosophila Georg Vogler1, Karen Ocorr1 1Development and Aging Program, The Sanford Burnham Institute for Medical Research JoVE 1425 Biologia
Semi-automated Optical Heartbeat Analysis of Small Hearts Karen Ocorr1, Martin Fink2, Anthony Cammarato1,3, Sanford I. Bernstein3, Rolf Bodmer1 1Development and Aging Program, The Sanford Burnham Institute for Medical Research, 2Cardiac Electrophysiology Group, Dept. of Physiology, Anatomy and Genetics, The Sanford Burnham Institute for Medical Research, 3Biology Department and Heart Institute, San Diego State University JoVE 1435 Biologia