Kathryn E. Saatman Spinal Cord and Brain Injury Research Center, Department of Physiology University of Kentucky Biography Publications Institution JoVE Articles Kathryn E. Saatman has not added a biography. If you are Kathryn E. Saatman and would like to personalize this page please email our Author Liaison for assistance. Publications Insulin-like Growth Factor-1 Overexpression Increases Long-term Survival of Posttrauma-born Hippocampal Neurons While Inhibiting Ectopic Migration Following Traumatic Brain Injury Acta Neuropathologica Communications. 04, 2020 | Pubmed ID: 32276671 Therapeutic Potential of Natural Compounds from Chinese Medicine in Acute and Subacute Phases of Ischemic Stroke Neural Regeneration Research. Mar, 2020 | Pubmed ID: 31571650 Fractionated Mitochondrial Magnetic Separation for Isolation of Synaptic Mitochondria from Brain Tissue Scientific Reports. 07, 2019 | Pubmed ID: 31273236 Noninvasive Noncontact Speckle Contrast Diffuse Correlation Tomography of Cerebral Blood Flow in Rats NeuroImage. 09, 2019 | Pubmed ID: 31112789 Acute Mitochondrial Impairment Underlies Prolonged Cellular Dysfunction After Repeated Mild Traumatic Brain Injuries Journal of Neurotrauma. 04, 2019 | Pubmed ID: 30417732 Experimental Designs for Repeated Mild Traumatic Brain Injury: Challenges and Considerations Journal of Neurotrauma. 04, 2019 | Pubmed ID: 30351225 Doxorubicin-induced Elevated Oxidative Stress and Neurochemical Alterations in Brain and Cognitive Decline: Protection by MESNA and Insights into Mechanisms of Chemotherapy-induced Cognitive Impairment ("chemobrain") Oncotarget. Jul, 2018 | Pubmed ID: 30100992 Assessment of Systemic Administration of PEGylated IGF-1 in a Mouse Model of Traumatic Brain Injury Restorative Neurology and Neuroscience. 2018 | Pubmed ID: 29889090 Pre-Clinical Testing of Therapies for Traumatic Brain Injury Journal of Neurotrauma. 12, 2018 | Pubmed ID: 29756522 Central Infusion of Insulin-Like Growth Factor-1 Increases Hippocampal Neurogenesis and Improves Neurobehavioral Function After Traumatic Brain Injury Journal of Neurotrauma. 07, 2018 | Pubmed ID: 29455576 Brain Microvascular Injury and White Matter Disease Provoked by Diabetes-associated Hyperamylinemia Annals of Neurology. Aug, 2017 | Pubmed ID: 28696548 IGF-1 Mediated Neurogenesis Involves a Novel RIT1/Akt/Sox2 Cascade Scientific Reports. 06, 2017 | Pubmed ID: 28607354 Repeated Closed Head Injury in Mice Results in Sustained Motor and Memory Deficits and Chronic Cellular Changes PloS One. 2016 | Pubmed ID: 27427961 Phage Display for Identification of Serum Biomarkers of Traumatic Brain Injury Journal of Neuroscience Methods. 10, 2016 | Pubmed ID: 27168498 Ablation of Matrix Metalloproteinase-9 Gene Decreases Cerebrovascular Permeability and Fibrinogen Deposition Post Traumatic Brain Injury in Mice Metabolic Brain Disease. Apr, 2015 | Pubmed ID: 24771110 Regional Neurodegeneration and Gliosis Are Amplified by Mild Traumatic Brain Injury Repeated at 24-hour Intervals Journal of Neuropathology and Experimental Neurology. Oct, 2014 | Pubmed ID: 25232942 Neuroinflammation and Neurologic Deficits in Diabetes Linked to Brain Accumulation of Amylin Molecular Neurodegeneration. Aug, 2014 | Pubmed ID: 25149184 Conditional Overexpression of Insulin-like Growth Factor-1 Enhances Hippocampal Neurogenesis and Restores Immature Neuron Dendritic Processes After Traumatic Brain Injury Journal of Neuropathology and Experimental Neurology. Aug, 2014 | Pubmed ID: 25003234 Astrocyte-Specific Overexpression of Insulin-Like Growth Factor-1 Protects Hippocampal Neurons and Reduces Behavioral Deficits Following Traumatic Brain Injury in Mice PloS One. 2013 | Pubmed ID: 23826235 Calpains Mediate Axonal Cytoskeleton Disintegration During Wallerian Degeneration Neurobiology of Disease. Aug, 2013 | Pubmed ID: 23542511 Brain Injury-induced Proteolysis is Reduced in a Novel Calpastatin-overexpressing Transgenic Mouse Journal of Neurochemistry. Jun, 2013 | Pubmed ID: 23305291 Rit GTPase Signaling Promotes Immature Hippocampal Neuronal Survival The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2012 | Pubmed ID: 22815504 Calpastatin Overexpression Limits Calpain-mediated Proteolysis and Behavioral Deficits Following Traumatic Brain Injury Experimental Neurology. Aug, 2012 | Pubmed ID: 22572592 Genetic Manipulation of Cell Death and Neuroplasticity Pathways in Traumatic Brain Injury Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics. Apr, 2012 | Pubmed ID: 22362424 Posttraumatic Mossy Fiber Sprouting is Related to the Degree of Cortical Damage in Three Mouse Strains Epilepsy Research. Mar, 2012 | Pubmed ID: 22047981 Rate of Neurodegeneration in the Mouse Controlled Cortical Impact Model is Influenced by Impactor Tip Shape: Implications for Mechanistic and Therapeutic Studies Journal of Neurotrauma. Nov, 2011 | Pubmed ID: 21341976 MicroRNAs in CNS Injury: Potential Roles and Therapeutic Implications BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology. Jan, 2011 | Pubmed ID: 21053309 Targeting Individual Calpain Isoforms for Neuroprotection Experimental Neurology. Nov, 2010 | Pubmed ID: 20682310 MiR-107 Regulates Granulin/progranulin with Implications for Traumatic Brain Injury and Neurodegenerative Disease The American Journal of Pathology. Jul, 2010 | Pubmed ID: 20489155 Calpain As a Therapeutic Target in Traumatic Brain Injury Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics. Jan, 2010 | Pubmed ID: 20129495 Temporal and Regional Changes in IGF-1/IGF-1R Signaling in the Mouse Brain After Traumatic Brain Injury Journal of Neurotrauma. Jan, 2010 | Pubmed ID: 19751099 Comparative Neuroprotective Effects of Cyclosporin A and NIM811, a Nonimmunosuppressive Cyclosporin A Analog, Following Traumatic Brain Injury Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jan, 2009 | Pubmed ID: 18714331 Classification of Traumatic Brain Injury for Targeted Therapies Journal of Neurotrauma. Jul, 2008 | Pubmed ID: 18627252 Differential Behavioral and Histopathological Responses to Graded Cortical Impact Injury in Mice Journal of Neurotrauma. Aug, 2006 | Pubmed ID: 16928182 Intra-Arterial Delivery of Neural Stem Cells to the Rat and Mouse Brain: Application to Cerebral Ischemia Bei Zhang1, Binoy Joseph2, Kathryn E. Saatman2, Lei Chen2 1College of Public Health, Shaanxi University of Chinese Medicine, 2Spinal Cord and Brain Injury Research Center, Department of Physiology, University of Kentucky JoVE 61119 Neurociência
Intra-Arterial Delivery of Neural Stem Cells to the Rat and Mouse Brain: Application to Cerebral Ischemia Bei Zhang1, Binoy Joseph2, Kathryn E. Saatman2, Lei Chen2 1College of Public Health, Shaanxi University of Chinese Medicine, 2Spinal Cord and Brain Injury Research Center, Department of Physiology, University of Kentucky JoVE 61119 Neurociência