Koji Furukawa Biomedical Research Institute National Institute of Advanced Industrial Science and Technology (AIST) Biography Publications Institution JoVE Articles Koji Furukawa has not added a biography. If you are Koji Furukawa and would like to personalize this page please email our Author Liaison for assistance. Publications Crystal structures of FMN-bound and FMN-free forms of dihydroorotate dehydrogenase from Trypanosoma bruceiFebs Open Bio. 2018 | Pubmed ID: An NMR Biochemical Assay for Fragment-Based Drug Discovery: Evaluation of an Inhibitor Activity on Spermidine Synthase of Trypanosoma cruziJournal of Medicinal Chemistry. 2016 | Pubmed ID: CD72 negatively regulates B lymphocyte responses to the lupus-related endogenous toll-like receptor 7 ligand Sm/RNPJournal of Experimental Medicine. 2016 | Pubmed ID: Inositol 1,4,5-trisphosphate receptor determines intracellular Ca2+ concentration in Trypanosoma cruzi throughout its life cycleFebs Open Bio. 2016 | Pubmed ID: Both mutated and unmutated memory B cells accumulate mutations in the course of the secondary response and develop a new antibody repertoireoptimally adapted to the secondary stimulusInternational Immunology. 2013 | Pubmed ID: Repression of the Transcription Factor Bach2 Contributes to Predisposition of IgG1 Memory B Cells toward Plasma Cell DifferentiationImmunity. 2013 | Pubmed ID: Association analysis of the NOD2 gene with susceptibility to graft-versus-host disease in a Japanese populationInternational Journal of Hematology. 2011 | Pubmed ID: Conformational analysis of human serum albumin and its non-enzymatic glycation products using monoclonal antibodiesJournal of Biochemistry. 2011 | Pubmed ID: Augmented Antibody Response with Premature Germinal Center Regression in CD40L Transgenic MiceJournal of Immunology. 2010 | Pubmed ID: An optimized procedure for efficient phage display of antibody fragments with a low folding efficiencyProtein Expression and Purification. 2009 | Pubmed ID: Efficient bacterial production of functional antibody fragments using a phagemid vectorProtein Expression and Purification. 2008 | Pubmed ID: Strategy for affinity maturation of an antibody with high evolvability to (4-hydroxy-3-nitrophenyl) acetyl haptenMolecular Immunology. 2007 | Pubmed ID: T cells specific to hapten-carrier but not to carrier alone assist in the production of anti-hapten and anti-carrier antibodiesInternational Immunology. 2007 | Pubmed ID: Initial repertoire of anti-(4-hydroxy-3-nitrophenylacetyl) antibodies as potential donors for effective affinity maturationMolecular Immunology. 2006 | Pubmed ID: A landscape for the dynamics of an immune responseBiochemical and Biophysical Research Communications. 2004 | Pubmed ID: BASH-deficient mice: limited primary repertoire and antibody formation, but sufficient affinity maturation and memory B cell generation, inanti-NP responseInternational Immunology. 2004 | Pubmed ID: Thermodynamic and kinetic aspects of antibody evolution during the immune response to haptenMolecular Immunology. 2003 | Pubmed ID: A role of the third complementarity-determining region in the affinity maturation of an antibodyJournal of Biological Chemistry. 2001 | Pubmed ID: Construction of an artificial tandem protein of the c-Myb DNA-binding domain and analysis of its DNA binding specificityBiochemical and Biophysical Research Communications. 1999 | Pubmed ID: Junctional amino acids determine the maturation pathway of an antibodyImmunity. 1999 | Pubmed ID: Kinetic analysis of DNA binding by the c-Myb DNA-binding domain using surface plasmon resonanceFebs Letters. 1999 | Pubmed ID: Thermodynamic analysis of protein induced folding upon DNA bindingOld and New Views of Protein Folding. 1999 | Pubmed ID: Thermodynamics of specific and non-specific DNA binding by the c-Myb DNA-binding domainJournal of Molecular Biology. 1998 | Pubmed ID: Identification of indispensable residues for specific DNA-binding in the imperfect tandem repeats of c-Myb R2R3Protein Engineering. 1997 | Pubmed ID: Residue 187 in c-Myb DNA-binding domain has a role to recognize the first pyrimidine in the consensus DNA sequenceProtein Engineering. 1997 | Pubmed ID: A small engineered protein lacks structural uniqueness by increasing the side-chain conformational entropyProceedings of the National Academy of Sciences of the United States of America. 1996 | Pubmed ID: IDENTIFICATION OF LYS(277) AT THE ACTIVE-SITE OF ESCHERICHIA-COLI GLYCOGEN-SYNTHASE - APPLICATION OF AFFINITY LABELING COMBINED WITHSITE-DIRECTED MUTAGENESISJournal of Biological Chemistry. 1994 | Pubmed ID: ROLE OF THE CONSERVED LYS-X-GLY-GLY SEQUENCE AT THE ADP-GLUCOSE-BINDING SITE IN ESCHERICHIA-COLI GLYCOGEN-SYNTHASEJournal of Biological Chemistry. 1993 | Pubmed ID: PROBING THE ACTIVE-SITE IN GLYCOGEN-SYNTHASE BY AFFINITY LABELING WITH NUCLEOTIDYL DERIVATIVES OF PYRIDOXAL-PHOSPHATEEnzymes Dependent on Pyridoxal Phosphate and Other Carbonyl Compounds As Cofactors. 1991 | Pubmed ID: IDENTIFICATION OF LYSINE-15 AT THE ACTIVE-SITE IN ESCHERICHIA-COLI GLYCOGEN-SYNTHASE - CONSERVATION OF A LYS-X-GLY-GLY SEQUENCE IN THEBACTERIAL AND MAMMALIAN ENZYMESJournal of Biological Chemistry. 1990 | Pubmed ID: FIBRINOGEN NAGOYA, A REPLACEMENT OF GLUTAMINE-329 BY ARGININE IN THE GAMMA-CHAIN THAT IMPAIRS THE POLYMERIZATION OF FIBRIN MONOMERJournal of Biochemistry. 1989 | Pubmed ID: Introduktion af et gen knockout direkte i den Amastigote fase af Trypanosoma cruzi ved hjælp af Crispr/Cas9 system Yukie Akutsu1, Motomichi Doi1, Koji Furukawa1, Yuko Takagi1 1Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST) JoVE 59962 Genética
Introduktion af et gen knockout direkte i den Amastigote fase af Trypanosoma cruzi ved hjælp af Crispr/Cas9 system Yukie Akutsu1, Motomichi Doi1, Koji Furukawa1, Yuko Takagi1 1Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST) JoVE 59962 Genética