Kostas Kostarelos Nanomedicine Lab, Faculty of Medical & Human Sciences University of Manchester Biography Publications Institution JoVE Articles Kostas Kostarelos has not added a biography. If you are Kostas Kostarelos and would like to personalize this page please email our Author Liaison for assistance. Publications Functionalized Carbon Nanotubes in the Brain: Cellular Internalization and Neuroinflammatory Responses PloS One. 2013 | Pubmed ID: 24260521 Carbon Nanotubes in Medicine & Biology - Therapy and Diagnostics Advanced Drug Delivery Reviews. Dec, 2013 | Pubmed ID: 24220279 Hemotoxicity of Carbon Nanotubes Advanced Drug Delivery Reviews. Dec, 2013 | Pubmed ID: 24211768 Carbon Nanotubes in Medicine and Biology - Safety and Toxicology Advanced Drug Delivery Reviews. Dec, 2013 | Pubmed ID: 24211669 Carbon Nanotubes As Vectors for Gene Therapy: Past Achievements, Present Challenges and Future Goals Advanced Drug Delivery Reviews. Dec, 2013 | Pubmed ID: 24184373 Pharmacology of Carbon Nanotubes: Toxicokinetics, Excretion and Tissue Accumulation Advanced Drug Delivery Reviews. Dec, 2013 | Pubmed ID: 24184372 How Do Functionalized Carbon Nanotubes Land On, Bind to and Pierce Through Model and Plasma Membranes Nanoscale. Nov, 2013 | Pubmed ID: 24056765 Ammonium and Guanidinium Dendron-Carbon Nanotubes by Amidation and Click Chemistry and Their Use for SiRNA Delivery Small (Weinheim an Der Bergstrasse, Germany). May, 2013 | Pubmed ID: 23650276 Esposizione DWCNT Polmonare Provoca Sostenute Locale E Di Basso Livello Sistemici Alterazioni Infiammatorie Nei Topi European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. Mar, 2013 | Pubmed ID: 23542608 Cationic Poly-L-lysine Dendrimer Complexes Doxorubicin and Delays Tumor Growth in Vitro and in Vivo ACS Nano. Mar, 2013 | Pubmed ID: 23527750 Prospects and Challenges of Graphene in Biomedical Applications Advanced Materials (Deerfield Beach, Fla.). Apr, 2013 | Pubmed ID: 23494834 Autophagy and Formation of Tubulovesicular Autophagosomes Provide a Barrier Against Nonviral Gene Delivery Autophagy. May, 2013 | Pubmed ID: 23422759 The Effective Nuclear Delivery of Doxorubicin from Dextran-coated Gold Nanoparticles Larger Than Nuclear Pores Biomaterials. Apr, 2013 | Pubmed ID: 23395274 In Vivo Cell Reprogramming Towards Pluripotency by Virus-free Overexpression of Defined Factors PloS One. 2013 | Pubmed ID: 23355895 Asbestos-like Pathogenicity of Long Carbon Nanotubes Alleviated by Chemical Functionalization Angewandte Chemie (International Ed. in English). Feb, 2013 | Pubmed ID: 23319294 Electroresponsive Polymer-carbon Nanotube Hydrogel Hybrids for Pulsatile Drug Delivery in Vivo Advanced Healthcare Materials. Jun, 2013 | Pubmed ID: 23184678 Purified Graphene Oxide Dispersions Lack in Vitro Cytotoxicity and in Vivo Pathogenicity Advanced Healthcare Materials. Mar, 2013 | Pubmed ID: 23184580 Safety Considerations for Graphene: Lessons Learnt from Carbon Nanotubes Accounts of Chemical Research. Mar, 2013 | Pubmed ID: 23163827 The Effect of Artificial Lipid Envelopment of Adenovirus 5 (Ad5) on Liver De-targeting and Hepatotoxicity Biomaterials. Jan, 2013 | Pubmed ID: 23146432 A High Poly(ethylene Glycol) Density on Graphene Nanomaterials Reduces the Detachment of Lipid-poly(ethylene Glycol) and Macrophage Uptake Acta Biomaterialia. Jan, 2013 | Pubmed ID: 22995407 Lipid-peptide Vesicle Nanoscale Hybrids for Triggered Drug Release by Mild Hyperthermia in Vitro and in Vivo ACS Nano. Oct, 2012 | Pubmed ID: 22857653 Liposome-gold Nanorod Hybrids for High-resolution Visualization Deep in Tissues Journal of the American Chemical Society. Aug, 2012 | Pubmed ID: 22852749 In Vivo Degradation of Functionalized Carbon Nanotubes After Stereotactic Administration in the Brain Cortex Nanomedicine (London, England). Oct, 2012 | Pubmed ID: 22712575 Degree of Chemical Functionalization of Carbon Nanotubes Determines Tissue Distribution and Excretion Profile Angewandte Chemie (International Ed. in English). Jun, 2012 | Pubmed ID: 22623333 Application of Carbon Nanotubes in Neurology: Clinical Perspectives and Toxicological Risks Archives of Toxicology. Jul, 2012 | Pubmed ID: 22547313 Therapeutics, Imaging and Toxicity of Nanomaterials in the Central Nervous System Journal of Controlled Release : Official Journal of the Controlled Release Society. Jul, 2012 | Pubmed ID: 22512901 Pharmacokinetics & Tissue Distribution of Temperature-sensitive Liposomal Doxorubicin in Tumor-bearing Mice Triggered with Mild Hyperthermia Biomaterials. Jun, 2012 | Pubmed ID: 22459195 Targeting Carbon Nanotubes Against Cancer Chemical Communications (Cambridge, England). Apr, 2012 | Pubmed ID: 22428156 Translocation Mechanisms of Chemically Functionalised Carbon Nanotubes Across Plasma Membranes Biomaterials. Apr, 2012 | Pubmed ID: 22289266 Carbon Nanotube-mediated Wireless Cell Permeabilization: Drug and Gene Uptake Nanomedicine (London, England). Dec, 2011 | Pubmed ID: 22122583 Diameter and Rigidity of Multiwalled Carbon Nanotubes Are Critical Factors in Mesothelial Injury and Carcinogenesis Proceedings of the National Academy of Sciences of the United States of America. Dec, 2011 | Pubmed ID: 22084097 Cellular Uptake and Cytotoxic Impact of Chemically Functionalized and Polymer-coated Carbon Nanotubes Small (Weinheim an Der Bergstrasse, Germany). Nov, 2011 | Pubmed ID: 21919194 Liposomes: from a Clinically Established Drug Delivery System to a Nanoparticle Platform for Theranostic Nanomedicine Accounts of Chemical Research. Oct, 2011 | Pubmed ID: 21812415 Making Carbon Nanotubes Biocompatible and Biodegradable Chemical Communications (Cambridge, England). Oct, 2011 | Pubmed ID: 21776531 Functional Motor Recovery from Brain Ischemic Insult by Carbon Nanotube-mediated SiRNA Silencing Proceedings of the National Academy of Sciences of the United States of America. Jul, 2011 | Pubmed ID: 21690348 Length-dependent Retention of Carbon Nanotubes in the Pleural Space of Mice Initiates Sustained Inflammation and Progressive Fibrosis on the Parietal Pleura The American Journal of Pathology. Jun, 2011 | Pubmed ID: 21641383 Antibody Covalent Immobilization on Carbon Nanotubes and Assessment of Antigen Binding Small (Weinheim an Der Bergstrasse, Germany). Aug, 2011 | Pubmed ID: 21608125 Cellular Uptake Mechanisms of Functionalised Multi-walled Carbon Nanotubes by 3D Electron Tomography Imaging Nanoscale. Jun, 2011 | Pubmed ID: 21603701 Cytotoxic Assessment of Carbon Nanotube Interaction with Cell Cultures Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21424457 Doxorubicin-loaded Lipid-quantum Dot Hybrids: Surface Topography and Release Properties International Journal of Pharmaceutics. Sep, 2011 | Pubmed ID: 21315141 Intracellular Trafficking and Gene Expression of PH-sensitive, Artificially Enveloped Adenoviruses in Vitro and in Vivo Biomaterials. Apr, 2011 | Pubmed ID: 21269689 The Alluring Potential of Functionalized Carbon Nanotubes in Drug Discovery Expert Opinion on Drug Discovery. Jul, 2010 | Pubmed ID: 22823208 Physiologically Based Pharmacokinetic Modeling of Nanoparticles ACS Nano. Nov, 2010 | Pubmed ID: 20945925 Hybrid Polymer-grafted Multiwalled Carbon Nanotubes for in Vitro Gene Delivery Small (Weinheim an Der Bergstrasse, Germany). Oct, 2010 | Pubmed ID: 20878655 Carbon Nanotubes: Fibrillar Pharmacology Nature Materials. Oct, 2010 | Pubmed ID: 20864939 Efficient Receptor-independent Intracellular Translocation of Aptamers Mediated by Conjugation to Carbon Nanotubes Chemical Communications (Cambridge, England). Oct, 2010 | Pubmed ID: 20830345 Filled and Glycosylated Carbon Nanotubes for in Vivo Radioemitter Localization and Imaging Nature Materials. Jun, 2010 | Pubmed ID: 20473287 Assessment of Cellular Uptake and Cytotoxicity of Carbon Nanotubes Using Flow Cytometry Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20422386 Nanorobots for Medicine: How Close Are We? Nanomedicine (London, England). Apr, 2010 | Pubmed ID: 20394527 Functionalized Carbon Nanotubes for Probing and Modulating Molecular Functions Chemistry & Biology. Feb, 2010 | Pubmed ID: 20189101 Enhanced Anticancer Activity of Multi-walled Carbon Nanotube-methotrexate Conjugates Using Cleavable Linkers Chemical Communications (Cambridge, England). Mar, 2010 | Pubmed ID: 20162159 Systemic Antiangiogenic Activity of Cationic Poly-L-lysine Dendrimer Delays Tumor Growth Proceedings of the National Academy of Sciences of the United States of America. Mar, 2010 | Pubmed ID: 20150514 Nanoparticles Functionalized with Recombinant Single Chain Fv Antibody Fragments (scFv) for the Magnetic Resonance Imaging of Cancer Cells Biomaterials. Feb, 2010 | Pubmed ID: 19889453 Chapter 17 - Engineering Cationic Liposome SiRNA Complexes for in Vitro and in Vivo Delivery Methods in Enzymology. 2009 | Pubmed ID: 19903563 Tumor Targeting of Functionalized Quantum Dot-liposome Hybrids by Intravenous Administration Molecular Pharmaceutics. Mar-Apr, 2009 | Pubmed ID: 19718803 Blood Circulation and Tissue Biodistribution of Lipid--quantum Dot (L-QD) Hybrid Vesicles Intravenously Administered in Mice Bioconjugate Chemistry. Sep, 2009 | Pubmed ID: 19655725 Synthesis and Characterization of a Carbon Nanotube-dendron Series for Efficient SiRNA Delivery Journal of the American Chemical Society. Jul, 2009 | Pubmed ID: 19555104 Antitumor Activity and Prolonged Survival by Carbon-nanotube-mediated Therapeutic SiRNA Silencing in a Human Lung Xenograft Model Small (Weinheim an Der Bergstrasse, Germany). May, 2009 | Pubmed ID: 19306454 Designer Adenoviruses for Nanomedicine and Nanodiagnostics Trends in Biotechnology. Apr, 2009 | Pubmed ID: 19251331 Synthesis and Analysis of Novel Glycerolipids for the Treatment of Metabolic Syndrome Journal of Medicinal Chemistry. Feb, 2009 | Pubmed ID: 19175322 Lipid-quantum Dot Bilayer Vesicles Enhance Tumor Cell Uptake and Retention in Vitro and in Vivo ACS Nano. Mar, 2008 | Pubmed ID: 19206564 Nanoengineering Artificial Lipid Envelopes Around Adenovirus by Self-assembly ACS Nano. May, 2008 | Pubmed ID: 19206502 Functionalized-quantum-dot-liposome Hybrids As Multimodal Nanoparticles for Cancer Small (Weinheim an Der Bergstrasse, Germany). Sep, 2008 | Pubmed ID: 18711753 Carbon-nanotube Shape and Individualization Critical for Renal Excretion Small (Weinheim an Der Bergstrasse, Germany). Aug, 2008 | Pubmed ID: 18666166 The Long and Short of Carbon Nanotube Toxicity Nature Biotechnology. Jul, 2008 | Pubmed ID: 18612299 Artificial Envelopment of Nonenveloped Viruses: Enhancing Adenovirus Tumor Targeting in Vivo FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Sep, 2008 | Pubmed ID: 18556649 Hype Around Nanotubes Creates Unrealistic Hopes Nature. May, 2008 | Pubmed ID: 18480788 Tissue Histology and Physiology Following Intravenous Administration of Different Types of Functionalized Multiwalled Carbon Nanotubes Nanomedicine (London, England). Apr, 2008 | Pubmed ID: 18373422 Opportunities and Challenges of Carbon-based Nanomaterials for Cancer Therapy Expert Opinion on Drug Delivery. Mar, 2008 | Pubmed ID: 18318654 Multiwalled Carbon Nanotube-doxorubicin Supramolecular Complexes for Cancer Therapeutics Chemical Communications (Cambridge, England). Jan, 2008 | Pubmed ID: 18188467 Functionalized Carbon Nanotubes in Drug Design and Discovery Accounts of Chemical Research. Jan, 2008 | Pubmed ID: 17867649 Cellular Uptake of Functionalized Carbon Nanotubes is Independent of Functional Group and Cell Type Nature Nanotechnology. Feb, 2007 | Pubmed ID: 18654229 Multifunctionalised Cationic Fullerene Adducts for Gene Transfer: Design, Synthesis and DNA Complexation Chemical Communications (Cambridge, England). Sep, 2007 | Pubmed ID: 17851620 Liposome-nanoparticle Hybrids for Multimodal Diagnostic and Therapeutic Applications Nanomedicine (London, England). Feb, 2007 | Pubmed ID: 17716195 Single-cell Dosimetry for Radioimmunotherapy of B-cell Lymphoma Patients with Special Reference to Leukemic Spread Cancer Biotherapy & Radiopharmaceuticals. Jun, 2007 | Pubmed ID: 17651041 Construction of Nanoscale Multicompartment Liposomes for Combinatory Drug Delivery International Journal of Pharmaceutics. Mar, 2007 | Pubmed ID: 17223294 The Emergence of Nanomedicine: a Field in the Making Nanomedicine (London, England). Jun, 2006 | Pubmed ID: 17716200 Establishing Nanomedicine Nanomedicine (London, England). Oct, 2006 | Pubmed ID: 17716156 Carbon Nanotubes As Nanomedicines: from Toxicology to Pharmacology Advanced Drug Delivery Reviews. Dec, 2006 | Pubmed ID: 17113677 Double Functionalization of Carbon Nanotubes for Multimodal Drug Delivery Chemical Communications (Cambridge, England). Mar, 2006 | Pubmed ID: 16518484 Tissue Biodistribution and Blood Clearance Rates of Intravenously Administered Carbon Nanotube Radiotracers Proceedings of the National Academy of Sciences of the United States of America. Feb, 2006 | Pubmed ID: 16492781 Functionalized Carbon Nanotubes As Emerging Nanovectors for the Delivery of Therapeutics Biochimica Et Biophysica Acta. Mar, 2006 | Pubmed ID: 16307724 Carbon Nanotubes: on the Road to Deliver Current Drug Delivery. Jul, 2005 | Pubmed ID: 16305427 What Role Can Chemistry Play in Cationic Liposome-Based Gene Therapy Research Today? Advances in Genetics. 2005 | Pubmed ID: 16243061 What Role Can Chemistry Play in Cationic Liposome-based Gene Therapy Research Today? Advances in Genetics. 2005 | Pubmed ID: 16240991 Synthetic, Self-assembly ABCD Nanoparticles; a Structural Paradigm for Viable Synthetic Non-viral Vectors Chemical Society Reviews. Nov, 2005 | Pubmed ID: 16239997 Applications of Carbon Nanotubes in Drug Delivery Current Opinion in Chemical Biology. Dec, 2005 | Pubmed ID: 16233988 Engineering Lipid Vesicles of Enhanced Intratumoral Transport Capabilities: Correlating Liposome Characteristics with Penetration into Human Prostate Tumor Spheroids Journal of Liposome Research. 2005 | Pubmed ID: 16194925 Synthesis and Application of Integrin Targeting Lipopeptides in Targeted Gene Delivery Chembiochem : a European Journal of Chemical Biology. Jul, 2005 | Pubmed ID: 15937988 Internal Microdosimetry for Single Cells in Radioimmunotherapy of B-cell Lymphoma Cancer Biotherapy & Radiopharmaceuticals. Apr, 2005 | Pubmed ID: 15869460 Binding and Condensation of Plasmid DNA Onto Functionalized Carbon Nanotubes: Toward the Construction of Nanotube-based Gene Delivery Vectors Journal of the American Chemical Society. Mar, 2005 | Pubmed ID: 15783221 Biomedical Applications of Functionalised Carbon Nanotubes Chemical Communications (Cambridge, England). Feb, 2005 | Pubmed ID: 15672140 Light-sensitive Fusion Between Polymer-coated Liposomes Following Physical Anchoring of Polymerisable Polymers Onto Lipid Bilayers by Self-assembly Faraday Discussions. 2005 | Pubmed ID: 15658785 Liposome-mediated Radiotherapeutics Within Avascular Tumor Spheroids: Comparative Dosimetry Study for Various Radionuclides, Liposome Systems, and a Targeting Antibody Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jan, 2005 | Pubmed ID: 15632038 Functionalized Carbon Nanotubes for Plasmid DNA Gene Delivery Angewandte Chemie (International Ed. in English). Oct, 2004 | Pubmed ID: 15455428 Binding and Interstitial Penetration of Liposomes Within Avascular Tumor Spheroids International Journal of Cancer. Journal International Du Cancer. Nov, 2004 | Pubmed ID: 15382056 Rational Design and Engineering of Delivery Systems for Therapeutics: Biomedical Exercises in Colloid and Surface Science Advances in Colloid and Interface Science. Dec, 2003 | Pubmed ID: 14672846 In vivo riprogrammazione di età somatiche celle a pluripotenza da iperespressione di fattori Yamanaka Açelya Yilmazer1, Irene de Lázaro1, Cyrill Bussy1, Kostas Kostarelos2 1Nanomedicine Lab, UCL School of Pharmacy, University College London, 2Nanomedicine Lab, Faculty of Medical & Human Sciences, University of Manchester Biologia
In vivo riprogrammazione di età somatiche celle a pluripotenza da iperespressione di fattori Yamanaka Açelya Yilmazer1, Irene de Lázaro1, Cyrill Bussy1, Kostas Kostarelos2 1Nanomedicine Lab, UCL School of Pharmacy, University College London, 2Nanomedicine Lab, Faculty of Medical & Human Sciences, University of Manchester Biologia