Lesley Mathews Griner Oncology Drug Discovery: Molecular Pharmacology Novartis Institutes for Biomedical Research Biography Publications Institution JoVE Articles Lesley Mathews Griner has not added a biography. If you are Lesley Mathews Griner and would like to personalize this page please email our Author Liaison for assistance. Publications Antitumor Properties of RAF709, a Highly Selective and Potent Inhibitor of RAF Kinase Dimers, in Tumors Driven by Mutant RAS or BRAF Cancer Research. Mar, 2018 | Pubmed ID: 29343524 Design and Discovery of N-(2-Methyl-5'-morpholino-6'-((tetrahydro-2H-pyran-4-yl)oxy)-[3,3'-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A Potent, Selective, and Efficacious RAF Inhibitor Targeting RAS Mutant Cancers Journal of Medicinal Chemistry. Jun, 2017 | Pubmed ID: 28557458 Поколение высокопроизводительных трехмерных опухоли сфероидов для скрининга наркотиков Lesley Mathews Griner1, Kalyani Gampa1, Toan Do2, Huyen Nguyen2, David Farley2, Christopher J. Hogan2, Douglas S. Auld2, Serena J. Silver1 1Oncology Drug Discovery: Molecular Pharmacology, Novartis Institutes for Biomedical Research, 2Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research JoVE 57476 Pesquisa do câncer
Поколение высокопроизводительных трехмерных опухоли сфероидов для скрининга наркотиков Lesley Mathews Griner1, Kalyani Gampa1, Toan Do2, Huyen Nguyen2, David Farley2, Christopher J. Hogan2, Douglas S. Auld2, Serena J. Silver1 1Oncology Drug Discovery: Molecular Pharmacology, Novartis Institutes for Biomedical Research, 2Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research JoVE 57476 Pesquisa do câncer
