Mahdi Ghani Tanz Centre for Research in Neurodegenerative Diseases University of Toronto Biography Publications Institution JoVE Articles Mahdi Ghani has not added a biography. If you are Mahdi Ghani and would like to personalize this page please email our Author Liaison for assistance. Publications An APOE-independent Cis-eSNP on Chromosome 19q13.32 Influences Tau Levels and Late-onset Alzheimer's Disease Risk Neurobiology of Aging. Jan, 2018 | Pubmed ID: 29395286 Characterizing Familial Corticobasal Syndrome Due to Alzheimer's Disease Pathology and PSEN1 Mutations Alzheimer's & Dementia : the Journal of the Alzheimer's Association. May, 2017 | Pubmed ID: 27743520 The ONDRISeq Panel: Custom-designed Next-generation Sequencing of Genes Related to Neurodegeneration NPJ Genomic Medicine. 2016 | Pubmed ID: 29263818 Genetic Variations in ABCA7 Can Increase Secreted Levels of Amyloid-β40 and Amyloid-β42 Peptides and ABCA7 Transcription in Cell Culture Models Journal of Alzheimer's Disease : JAD. 06, 2016 | Pubmed ID: 27314524 Genetic and Epigenetic Study of ALS-discordant Identical Twins with Double Mutations in SOD1 and ARHGEF28 Journal of Neurology, Neurosurgery, and Psychiatry. 11, 2016 | Pubmed ID: 27154192 Mutation Analysis of the MS4A and TREM Gene Clusters In a case-control Alzheimer's Disease Data Set Neurobiology of Aging. 06, 2016 | Pubmed ID: 27084067 Novel GRN Mutations in Patients with Corticobasal Syndrome Scientific Reports. Mar, 2016 | Pubmed ID: 26961809 Mutation Analysis of CHCHD2 in Canadian Patients with Familial Parkinson's Disease Neurobiology of Aging. Feb, 2016 | Pubmed ID: 26639156 MTHFSD and DDX58 Are Novel RNA-binding Proteins Abnormally Regulated in Amyotrophic Lateral Sclerosis Brain : a Journal of Neurology. Jan, 2016 | Pubmed ID: 26525917 Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals JAMA Neurology. Nov, 2015 | Pubmed ID: 26366463 Rare Coding Mutations Identified by Sequencing of Alzheimer Disease Genome-wide Association Studies Loci Annals of Neurology. Sep, 2015 | Pubmed ID: 26101835 Mutation Analysis of CHCHD10 in Different Neurodegenerative Diseases Brain : a Journal of Neurology. Sep, 2015 | Pubmed ID: 25833818 Inbreeding Among Caribbean Hispanics from the Dominican Republic and Its Effects on Risk of Alzheimer Disease Genetics in Medicine : Official Journal of the American College of Medical Genetics. Aug, 2015 | Pubmed ID: 25394174 Coding Mutations in SORL1 and Alzheimer Disease Annals of Neurology. Feb, 2015 | Pubmed ID: 25382023 Mutation Analysis of Patients with Neurodegenerative Disorders Using NeuroX Array Neurobiology of Aging. Jan, 2015 | Pubmed ID: 25174650 Identical Twins with the C9orf72 Repeat Expansion Are Discordant for ALS Neurology. Oct, 2014 | Pubmed ID: 25209579 Evidence of Recessive Alzheimer Disease Loci in a Caribbean Hispanic Data Set: Genome-wide Survey of Runs of Homozygosity JAMA Neurology. Oct, 2013 | Pubmed ID: 23978990 Hypermethylation of the CpG Island Near the G4C2 Repeat in ALS with a C9orf72 Expansion American Journal of Human Genetics. Jun, 2013 | Pubmed ID: 23731538 Role of P73 in Alzheimer Disease: Lack of Association in Mouse Models or in Human Cohorts Molecular Neurodegeneration. Feb, 2013 | Pubmed ID: 23414597 Segmental Duplications in Genome-wide Significant Loci and Housekeeping Genes; Warning for GAPDH and ACTB Neurobiology of Aging. Jun, 2013 | Pubmed ID: 23238109 Investigation of C9orf72 in 4 Neurodegenerative Disorders Archives of Neurology. Sep, 2012 | Pubmed ID: 22964832 Genetic Association of CR1 with Alzheimer's Disease: a Tentative Disease Mechanism Neurobiology of Aging. Dec, 2012 | Pubmed ID: 22819390 Epidemiology and Genetics of Frontotemporal Dementia: a Door-to-door Survey in Southern Italy Neurobiology of Aging. Dec, 2012 | Pubmed ID: 22819134 Genome-wide Survey of Large Rare Copy Number Variants in Alzheimer's Disease Among Caribbean Hispanics G3 (Bethesda, Md.). Jan, 2012 | Pubmed ID: 22384383 Next-generation Sequencing en Bioinformatics pijpleiding om te evalueren van genetische determinanten van constitutionele ziekte gericht Allison A. Dilliott1,2, Sali M.K. Farhan3, Mahdi Ghani4, Christine Sato4, Eric Liang5, Ming Zhang4, Adam D. McIntyre1, Henian Cao1, Lemuel Racacho6,7, John F. Robinson1, Michael J. Strong1,8, Mario Masellis9,10, Dennis E. Bulman6,7, Ekaterina Rogaeva4, Anthony Lang10,11, Carmela Tartaglia4,10, Elizabeth Finger12,13, Lorne Zinman9, John Turnbull14, Morris Freedman10,15, Rick Swartz9, Sandra E. Black9,16, Robert A. Hegele1,2 1Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, 2Department of Biochemistry, Schulich School of Medicine and Dentistry, Western University, 3Analytic and Translational Genetics Unit, Center for Genomic Medicine, Harvard Medical School, Massachusetts General Hospital, Stanley Centre for Psychiatric Research, Broad Institute of MIT and Harvard, 4Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, 5School of Medicine, Faculty of Health Sciences, Queen's University, 6Faculty of Medicine, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, 7CHEO Research Institute, Faculty of Medicine, University of Ottawa, 8Department of Clinical Neurological Sciences, Western University, 9Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, 10Division of Neurology, Department of Medicine, University of Toronto, 11Morton and Gloria Shulman Movement Disorders Centre, Toronto Western Hospital, 12Department of Clinical Neurological Sciences, Schulich School of Medicine and Dentistry, Western University, 13Parkwood Institute, St. Joseph's Health Care, 14Department of Medicine, Division of Neurology, McMaster University, 15Division of Neurology, Department of Medicine, Baycrest Health Sciences, 16Canadian Partnership for Stroke Recovery Sunnybrook Site, Sunnybrook Health Science Centre, University of Toronto JoVE 57266 Genética
Next-generation Sequencing en Bioinformatics pijpleiding om te evalueren van genetische determinanten van constitutionele ziekte gericht Allison A. Dilliott1,2, Sali M.K. Farhan3, Mahdi Ghani4, Christine Sato4, Eric Liang5, Ming Zhang4, Adam D. McIntyre1, Henian Cao1, Lemuel Racacho6,7, John F. Robinson1, Michael J. Strong1,8, Mario Masellis9,10, Dennis E. Bulman6,7, Ekaterina Rogaeva4, Anthony Lang10,11, Carmela Tartaglia4,10, Elizabeth Finger12,13, Lorne Zinman9, John Turnbull14, Morris Freedman10,15, Rick Swartz9, Sandra E. Black9,16, Robert A. Hegele1,2 1Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, 2Department of Biochemistry, Schulich School of Medicine and Dentistry, Western University, 3Analytic and Translational Genetics Unit, Center for Genomic Medicine, Harvard Medical School, Massachusetts General Hospital, Stanley Centre for Psychiatric Research, Broad Institute of MIT and Harvard, 4Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, 5School of Medicine, Faculty of Health Sciences, Queen's University, 6Faculty of Medicine, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, 7CHEO Research Institute, Faculty of Medicine, University of Ottawa, 8Department of Clinical Neurological Sciences, Western University, 9Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, 10Division of Neurology, Department of Medicine, University of Toronto, 11Morton and Gloria Shulman Movement Disorders Centre, Toronto Western Hospital, 12Department of Clinical Neurological Sciences, Schulich School of Medicine and Dentistry, Western University, 13Parkwood Institute, St. Joseph's Health Care, 14Department of Medicine, Division of Neurology, McMaster University, 15Division of Neurology, Department of Medicine, Baycrest Health Sciences, 16Canadian Partnership for Stroke Recovery Sunnybrook Site, Sunnybrook Health Science Centre, University of Toronto JoVE 57266 Genética