Muniswamy Madesh Department of Biochemistry Temple University Biography Publications Institution JoVE Articles Muniswamy Madesh has not added a biography. If you are Muniswamy Madesh and would like to personalize this page please email our Author Liaison for assistance. Publications Membrane-Tethered MUC1 Mucin Is Phosphorylated by Epidermal Growth Factor Receptor in Airway Epithelial Cells and Associates with TLR5 To Inhibit Recruitment of MyD88 Journal of Immunology (Baltimore, Md. : 1950). Feb, 2012 | Pubmed ID: 22250084 Hypoxia-induced Acidosis Uncouples the STIM-Orai Calcium Signaling Complex The Journal of Biological Chemistry. Dec, 2011 | Pubmed ID: 22084246 Sensing Cellular Stress Through STIM Proteins Nature Chemical Biology. Aug, 2011 | Pubmed ID: 21769090 Requirement of FADD, NEMO, and BAX/BAK for Aberrant Mitochondrial Function in Tumor Necrosis Factor Alpha-induced Necrosis Molecular and Cellular Biology. Sep, 2011 | Pubmed ID: 21746883 Hyperhomocysteinemia Impairs Endothelium-derived Hyperpolarizing Factor-mediated Vasorelaxation in Transgenic Cystathionine Beta Synthase-deficient Mice Blood. Aug, 2011 | Pubmed ID: 21653942 NF-kappaB Protects Cells from Gamma Interferon-induced RIP1-dependent Necroptosis Molecular and Cellular Biology. Jul, 2011 | Pubmed ID: 21576359 PECAM-targeted Delivery of SOD Inhibits Endothelial Inflammatory Response FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jan, 2011 | Pubmed ID: 20876216 Acidic NAADP-sensitive Calcium Stores in the Endothelium: Agonist-specific Recruitment and Role in Regulating Blood Pressure The Journal of Biological Chemistry. Nov, 2010 | Pubmed ID: 20876534 S-glutathionylation Activates STIM1 and Alters Mitochondrial Homeostasis The Journal of Cell Biology. Aug, 2010 | Pubmed ID: 20679432 Mitochondrial Complex II Prevents Hypoxic but Not Calcium- and Proapoptotic Bcl-2 Protein-induced Mitochondrial Membrane Potential Loss The Journal of Biological Chemistry. Aug, 2010 | Pubmed ID: 20566649 Nitration of the Mitochondrial Complex I Subunit NDUFB8 Elicits RIP1- and RIP3-mediated Necrosis Free Radical Biology & Medicine. Jan, 2010 | Pubmed ID: 19897030 Melanocyte-like Cells in the Heart and Pulmonary Veins Contribute to Atrial Arrhythmia Triggers The Journal of Clinical Investigation. Nov, 2009 | Pubmed ID: 19855129 Execution of Superoxide-induced Cell Death by the Proapoptotic Bcl-2-related Proteins Bid and Bak Molecular and Cellular Biology. Jun, 2009 | Pubmed ID: 19332555 Carcinoembryonic Cell Adhesion Molecule 6 in Human Lung: Regulated Expression of a Multifunctional Type II Cell Protein American Journal of Physiology. Lung Cellular and Molecular Physiology. Jun, 2009 | Pubmed ID: 19329538 Bad Targets the Permeability Transition Pore Independent of Bax or Bak to Switch Between Ca2+-dependent Cell Survival and Death Molecular Cell. Feb, 2009 | Pubmed ID: 19217411 Inhalational Anesthetics Induce Cell Damage by Disruption of Intracellular Calcium Homeostasis with Different Potencies Anesthesiology. Aug, 2008 | Pubmed ID: 18648233 Caveolae Are an Essential Component of the Pathway for Endothelial Cell Signaling Associated with Abrupt Reduction of Shear Stress Biochimica Et Biophysica Acta. Oct, 2008 | Pubmed ID: 18573285 The Common Inhalational Anesthetic Isoflurane Induces Apoptosis Via Activation of Inositol 1,4,5-trisphosphate Receptors Anesthesiology. Feb, 2008 | Pubmed ID: 18212570 Endothelial Targeting of Semi-permeable Polymer Nanocarriers for Enzyme Therapies Biomaterials. Jan, 2008 | Pubmed ID: 17950837 Simultaneous Detection of Apoptosis and Mitochondrial Superoxide Production in Live Cells by Flow Cytometry and Confocal Microscopy Nature Protocols. 2007 | Pubmed ID: 17853886 G Protein-coupled Receptor Ca2+-linked Mitochondrial Reactive Oxygen Species Are Essential for Endothelial/leukocyte Adherence Molecular and Cellular Biology. Nov, 2007 | Pubmed ID: 17724077 The Proapoptotic Factors Bax and Bak Regulate T Cell Proliferation Through Control of Endoplasmic Reticulum Ca(2+) Homeostasis Immunity. Aug, 2007 | Pubmed ID: 17692540 ABCA3 is Critical for Lamellar Body Biogenesis in Vivo The Journal of Biological Chemistry. Aug, 2007 | Pubmed ID: 17540762 Superoxide Flux in Endothelial Cells Via the Chloride Channel-3 Mediates Intracellular Signaling Molecular Biology of the Cell. Jun, 2007 | Pubmed ID: 17360969 The HIV-1 Vpr and Glucocorticoid Receptor Complex is a Gain-of-function Interaction That Prevents the Nuclear Localization of PARP-1 Nature Cell Biology. Feb, 2006 | Pubmed ID: 16429131 Functional and Trafficking Defects in ATP Binding Cassette A3 Mutants Associated with Respiratory Distress Syndrome The Journal of Biological Chemistry. Apr, 2006 | Pubmed ID: 16415354 Lung Endothelial Cell Proliferation with Decreased Shear Stress is Mediated by Reactive Oxygen Species American Journal of Physiology. Cell Physiology. Jan, 2006 | Pubmed ID: 16107509 Selective Role for Superoxide in InsP3 Receptor-mediated Mitochondrial Dysfunction and Endothelial Apoptosis The Journal of Cell Biology. Sep, 2005 | Pubmed ID: 16186254 The Endoplasmic Reticulum Gateway to Apoptosis by Bcl-X(L) Modulation of the InsP3R Nature Cell Biology. Oct, 2005 | Pubmed ID: 16179951 Proliferative Signaling by Store-operated Calcium Channels Opposes Colon Cancer Cell Cytostasis Induced by Bacterial Enterotoxins The Journal of Pharmacology and Experimental Therapeutics. Sep, 2005 | Pubmed ID: 15937149 A Surfactant Protein C Precursor Protein BRICHOS Domain Mutation Causes Endoplasmic Reticulum Stress, Proteasome Dysfunction, and Caspase 3 Activation American Journal of Respiratory Cell and Molecular Biology. Jun, 2005 | Pubmed ID: 15778495 Involvement of Transforming Growth Factor-beta in Regulation of Calcium Transients in Diabetic Vascular Smooth Muscle Cells American Journal of Physiology. Renal Physiology. Dec, 2003 | Pubmed ID: 12876066 The Polypeptide Chain-releasing Factor GSPT1/eRF3 is Proteolytically Processed into an IAP-binding Protein The Journal of Biological Chemistry. Oct, 2003 | Pubmed ID: 12865429 Calcium Signaling and Apoptosis Biochemical and Biophysical Research Communications. May, 2003 | Pubmed ID: 12729578 TcBid Promotes Ca(2+) Signal Propagation to the Mitochondria: Control of Ca(2+) Permeation Through the Outer Mitochondrial Membrane The EMBO Journal. May, 2002 | Pubmed ID: 11980717 TGF-beta-induced Ca(2+) Influx Involves the Type III IP(3) Receptor and Regulates Actin Cytoskeleton American Journal of Physiology. Renal Physiology. May, 2002 | Pubmed ID: 11934702 Rapid Kinetics of TBid-induced Cytochrome C and Smac/DIABLO Release and Mitochondrial Depolarization The Journal of Biological Chemistry. Feb, 2002 | Pubmed ID: 11741882 Visualization of Vascular Ca2+ Signaling Triggered by Paracrine Derived ROS Karthik Mallilankaraman1, Rajesh Kumar Gandhirajan1, Brian J. Hawkins2, Muniswamy Madesh1 1Department of Biochemistry, Temple University, 2Department of Anesthesiology and Pain Medicine, University of Washington JoVE 3511 Biologia
Visualization of Vascular Ca2+ Signaling Triggered by Paracrine Derived ROS Karthik Mallilankaraman1, Rajesh Kumar Gandhirajan1, Brian J. Hawkins2, Muniswamy Madesh1 1Department of Biochemistry, Temple University, 2Department of Anesthesiology and Pain Medicine, University of Washington JoVE 3511 Biologia