Pampee P. Young Department of Pathology, Microbiology, and Immunology Vanderbilt University Medical Center Biography Publications Institution JoVE Articles Pampee P. Young has not added a biography. If you are Pampee P. Young and would like to personalize this page please email our Author Liaison for assistance. Publications An Exploration of the Advantages of Automated Titration Testing: Low Inter-instrument Variability and Equivalent Accuracy for ABO and Non-ABO Antibody Titres Relative to Tube Testing Vox Sanguinis. Feb, 2020 | Pubmed ID: 32052467 Identification of a Pro-angiogenic Functional Role for FSP1-positive Fibroblast Subtype in Wound Healing Nature Communications. 07, 2019 | Pubmed ID: 31289275 Making Whole Blood for Trauma Available (again): the AMERICAN Red Cross Experience Transfusion. 04, 2019 | Pubmed ID: 30980746 Inhibition of Wnt/β-catenin Signaling Ameliorates Osteoarthritis in a Murine Model of Experimental Osteoarthritis JCI Insight. 02, 2018 | Pubmed ID: 29415892 Acute Autoimmune Hemolytic Anemia Due to Anti-En Autoantibody Successfully Treated with Rituximab Transfusion. 01, 2018 | Pubmed ID: 29023757 Significantly Enhanced Testing Sensitivities of Automated ORTHO VISION Analyzers Detect Weak D Phenotypes Transfusion. 11, 2017 | Pubmed ID: 29105829 Loss of SPRR3 in ApoE-/- Mice Leads to Atheroma Vulnerability Through Akt Dependent and Independent Effects in VSMCs PloS One. 2017 | Pubmed ID: 28886156 Temporary, Systemic Inhibition of the WNT/β-Catenin Pathway Promotes Regenerative Cardiac Repair Following Myocardial Infarct Cell, Stem Cells and Regenerative Medicine. Nov, 2016 | Pubmed ID: 28042617 Wnt/β-catenin Pathway in Tissue Injury: Roles in Pathology and Therapeutic Opportunities for Regeneration FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 10, 2016 | Pubmed ID: 27335371 Inhibition of Wnt/β-catenin Pathway Promotes Regenerative Repair of Cutaneous and Cartilage Injury FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Dec, 2015 | Pubmed ID: 26268926 Eculizumab Inhibits Hemolysis in a Model of ABO-incompatible Red Blood Cell Transfusion Transfusion. Jul, 2015 | Pubmed ID: 26172150 Cell-based Therapies for Cardiac Disease: a Cellular Therapist's Perspective Transfusion. Feb, 2015 | Pubmed ID: 25145464 Crosslinkable Gelatin Hydrogels for Vasculogenic Induction and Delivery of Mesenchymal Stem Cells Advanced Functional Materials. Nov, 2014 | Pubmed ID: 26327818 Identification of Small Proline-rich Repeat Protein 3 As a Novel Atheroprotective Factor That Promotes Adaptive Akt Signaling in Vascular Smooth Muscle Cells Arteriosclerosis, Thrombosis, and Vascular Biology. Dec, 2014 | Pubmed ID: 25278290 Clinically Significant Hemolytic Disease of the Newborn Secondary to Passive Transfer of Anti-D from Maternal RhIG Transfusion. Nov, 2014 | Pubmed ID: 24826985 Commercially Available Blood-group Antibodies May Be Used to Visualize Blood Group A Antigen in Paraffin-embedded Tissue Sections Archives of Pathology & Laboratory Medicine. Feb, 2014 | Pubmed ID: 24476512 Membrane TNF-alpha-activated Programmed Necrosis is Mediated by Ceramide-induced Reactive Oxygen Species Journal of Molecular Signaling. Nov, 2013 | Pubmed ID: 24180579 Brown Recluse Spider Bite Mediated Hemolysis: Clinical Features, a Possible Role for Complement Inhibitor Therapy, and Reduced RBC Surface Glycophorin A As a Potential Biomarker of Venom Exposure PloS One. 2013 | Pubmed ID: 24086749 Membrane Versus Soluble Isoforms of TNF-α Exert Opposing Effects on Tumor Growth and Survival of Tumor-associated Myeloid Cells Cancer Research. Jul, 2013 | Pubmed ID: 23704210 Human Mesenchymal Stromal Cells: Identifying Assays to Predict Potency for Therapeutic Selection Stem Cells Translational Medicine. Feb, 2013 | Pubmed ID: 23362238 Blood Group A Antigen Expression on Cardiac Endothelium is Highly Individualized: Possible Implications for Transplantation Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology. Jul-Aug, 2013 | Pubmed ID: 23290353 A Physiological Role for Connective Tissue Growth Factor in Early Wound Healing Laboratory Investigation; a Journal of Technical Methods and Pathology. Jan, 2013 | Pubmed ID: 23212098 Pyrvinium, a Potent Small Molecule Wnt Inhibitor, Increases Engraftment and Inhibits Lineage Commitment of Mesenchymal Stem Cells (MSCs) Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. Feb, 2012 | Pubmed ID: 22332749 Transfusion Medicine Illustrated. Profound Piperacillin-mediated Drug-induced Immune Hemolysis in a Patient with Cystic Fibrosis Transfusion. Jan, 2012 | Pubmed ID: 22032241 Molecular Mediators of Mesenchymal Stem Cell Biology Vitamins and Hormones. 2011 | Pubmed ID: 22127236 Lessons from Genetically Altered Mesenchymal Stem Cells (MSCs); Candidates for Improved MSC-Directed Myocardial Repair Cell Transplantation. Nov, 2011 | Pubmed ID: 22080676 Pyrvinium, a Potent Small Molecule Wnt Inhibitor, Promotes Wound Repair and Post-MI Cardiac Remodeling PloS One. 2010 | Pubmed ID: 21170416 SFRP2 Suppression of Bone Morphogenic Protein (BMP) and Wnt Signaling Mediates Mesenchymal Stem Cell (MSC) Self-renewal Promoting Engraftment and Myocardial Repair The Journal of Biological Chemistry. Nov, 2010 | Pubmed ID: 20826809 Atheromas Feel the Pressure: Biomechanical Stress and Atherosclerosis The American Journal of Pathology. Jul, 2010 | Pubmed ID: 20558573 Proteomic Analysis of Osteogenic Sarcoma: Association of Tumour Necrosis Factor with Poor Prognosis International Journal of Experimental Pathology. Aug, 2010 | Pubmed ID: 20353421 Biomechanical Stress Induces Novel Arterial Intima-enriched Genes: Implications for Vascular Adaptation to Stress Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology. Mar-Apr, 2010 | Pubmed ID: 19211270 Predefined Massive Transfusion Protocols Are Associated with a Reduction in Organ Failure and Postinjury Complications The Journal of Trauma. Jan, 2009 | Pubmed ID: 19131804 Low Levels of Tumor Necrosis Factor Alpha Increase Tumor Growth by Inducing an Endothelial Phenotype of Monocytes Recruited to the Tumor Site Cancer Research. Jan, 2009 | Pubmed ID: 19118019 Regulation of the Atheroma-enriched Protein, SPRR3, in Vascular Smooth Muscle Cells Through Cyclic Strain is Dependent on Integrin Alpha1beta1/collagen Interaction The American Journal of Pathology. Nov, 2008 | Pubmed ID: 18832573 Damage Control Hematology: the Impact of a Trauma Exsanguination Protocol on Survival and Blood Product Utilization The Journal of Trauma. May, 2008 | Pubmed ID: 18469638 Biologic Properties of Endothelial Progenitor Cells and Their Potential for Cell Therapy Progress in Cardiovascular Diseases. May-Jun, 2007 | Pubmed ID: 17498522 The Origin and in Vivo Significance of Murine and Human Culture-expanded Endothelial Progenitor Cells The American Journal of Pathology. May, 2006 | Pubmed ID: 16651636 Enrichment of Genes in the Aortic Intima That Are Associated with Stratified Epithelium: Implications of Underlying Biomechanical and Barrier Properties of the Arterial Intima Circulation. May, 2005 | Pubmed ID: 15867175 Blood Donor White Blood Cell Reduction Filters As a Source of Human Peripheral Blood-derived Endothelial Progenitor Cells Transfusion. Jan, 2005 | Pubmed ID: 15647014 VEGF Disrupts the Neonatal Blood-brain Barrier and Increases Life Span After Non-ablative BMT in a Murine Model of Congenital Neurodegeneration Caused by a Lysosomal Enzyme Deficiency Experimental Neurology. Jul, 2004 | Pubmed ID: 15191807 Isolation and Characterization of Adult Cardiac Fibroblasts and Myofibroblasts Meiling Melzer1, David Beier1, Pampee P. Young1,2, Sarika Saraswati1 1Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, 2American Red Cross, National Headquarters JoVE 60909 Biologia
Isolation and Characterization of Adult Cardiac Fibroblasts and Myofibroblasts Meiling Melzer1, David Beier1, Pampee P. Young1,2, Sarika Saraswati1 1Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, 2American Red Cross, National Headquarters JoVE 60909 Biologia