Philipp Dutkowski Swiss HPB Laboratory, Department of Visceral & Transplant Surgery University Hospital Zürich Biography Publications Institution JoVE Articles Philipp Dutkowski has not added a biography. If you are Philipp Dutkowski and would like to personalize this page please email our Author Liaison for assistance. Publications Obstacles to Implement Machine Perfusion Technology in Routine Clinical Practice of Transplantation - Why Are We Not There Yet ? Hepatology (Baltimore, Md.). Apr, 2023 | Pubmed ID: 37013926 Utilization of Livers Donated After Circulatory Death for Transplantation - An International Comparison Journal of Hepatology. Feb, 2023 | Pubmed ID: 36740047 A Multicenter Randomized-controlled Trial of Hypothermic Oxygenated Perfusion (HOPE) for Human Liver Grafts Before Transplantation Journal of Hepatology. Apr, 2023 | Pubmed ID: 36681160 Observations and Findings During the Development of a Subnormothermic/normothermic Long-term Ex Vivo Liver Perfusion Machine Artificial Organs. Feb, 2023 | Pubmed ID: 36106378 Machine Perfusion for Extended Criteria Donor Livers: What Challenges Remain? Journal of Clinical Medicine. Sep, 2022 | Pubmed ID: 36079148 Mitochondria and Cancer Recurrence After Liver Transplantation-What Is the Benefit of Machine Perfusion? International Journal of Molecular Sciences. Aug, 2022 | Pubmed ID: 36077144 Controversy Over Liver Transplantation or Resection for Neuroendocrine Liver Metastasis: Tumor Biology Cuts the Deal Annals of Surgery. Aug, 2022 | Pubmed ID: 35975918 Mitochondria and Ischemia Reperfusion Injury Current Opinion in Organ Transplantation. Oct, 2022 | Pubmed ID: 35950880 Liver Transplantation As a New Standard of Care in Patients With Perihilar Cholangiocarcinoma? Results From an International Benchmark Study Annals of Surgery. Nov, 2022 | Pubmed ID: 35894433 Novel Benchmark Values for Redo Liver Transplantation: Does the Outcome Justify the Effort? Annals of Surgery. Nov, 2022 | Pubmed ID: 35894428 Impact of Machine Perfusion on the Immune Response After Liver Transplantation - A Primary Treatment or Just a Delivery Tool Frontiers in Immunology. 2022 | Pubmed ID: 35874758 Low-dose Aspirin Confers Protection Against Acute Cellular Allograft Rejection After Primary Liver Transplantation Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Jun, 2022 | Pubmed ID: 35735232 Corrigendum to 'Protective Mechanisms and Current Clinical Evidence of Hypothermic Oxygenated Machine Perfusion (HOPE) in Preventing Post-transplant Cholangiopathy' [J Hepatol 76 (2022) 1330-1347] Journal of Hepatology. Sep, 2022 | Pubmed ID: 35718635 Transplantation of a Human Liver Following 3 Days of Ex Situ Normothermic Preservation Nature Biotechnology. Nov, 2022 | Pubmed ID: 35641829 Protective Mechanisms and Current Clinical Evidence of Hypothermic Oxygenated Machine Perfusion (HOPE) in Preventing Post-transplant Cholangiopathy Journal of Hepatology. Jun, 2022 | Pubmed ID: 35589254 Machine Perfusion in Liver Transplantation Hepatology (Baltimore, Md.). Nov, 2022 | Pubmed ID: 35488496 Liver Perfusion Strategies: What is Best and Do Ischemia Times Still Matter? Current Opinion in Organ Transplantation. Aug, 2022 | Pubmed ID: 35438271 Prolonged Preservation by Hypothermic Machine Perfusion Facilitates Logistics in Liver Transplantation: A European Observational Cohort Study American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Jul, 2022 | Pubmed ID: 35315202 A Multicentre Outcome Analysis to Define Global Benchmarks for Donation After Circulatory Death Liver Transplantation Journal of Hepatology. Feb, 2022 | Pubmed ID: 34655663 Synthesis of Coagulation Factors During Long-term Ex Situ Liver Perfusion Artificial Organs. Feb, 2022 | Pubmed ID: 34287985 Long-term Normothermic Machine Preservation of Partial Livers: First Experience With 21 Human Hemi-livers Annals of Surgery. Nov, 2021 | Pubmed ID: 34334640 Hypothermic Oxygenated Machine Perfusion Protects From Cholangiopathy in Donation After Circulatory Death Liver Transplantation Hepatology (Baltimore, Md.). Dec, 2021 | Pubmed ID: 34233012 Letter to the Editor: The Concept of Real-Time Spectroscopy for Liver Viability Assessment Hepatology (Baltimore, Md.). Oct, 2021 | Pubmed ID: 33942337 Sources and Prevention of Graft Infection During Long-term Ex Situ Liver Perfusion Transplant Infectious Disease : an Official Journal of the Transplantation Society. Aug, 2021 | Pubmed ID: 33887094 Adherence To, and Patient Convenience Of, Prolonged-release Tacrolimus in Stable Kidney and Liver Transplant Recipients After Conversion from Immediate-release Tacrolimus in Routine Clinical Practice in Switzerland Swiss Medical Weekly. Feb, 2021 | Pubmed ID: 33638353 Multimodal Treatment Strategies for Colorectal Liver Metastases Swiss Medical Weekly. Feb, 2021 | Pubmed ID: 33631027 Viability Assessment in Liver Transplantation-What Is the Impact of Dynamic Organ Preservation? Biomedicines. Feb, 2021 | Pubmed ID: 33562406 Bile Formation in Long-term Ex Situ Perfused Livers Surgery. Apr, 2021 | Pubmed ID: 33422346 The Importance of Adequate Oxygenation During Hypothermic Machine Perfusion JHEP Reports : Innovation in Hepatology. Feb, 2021 | Pubmed ID: 33305200 Response to the Comment on "Injury or Function-What Is Best to Assess Organ Viability Before Liver Graft Implantation?" Annals of Surgery. Dec, 2021 | Pubmed ID: 33064397 Hypothermic, Oxygenated Perfusion (HOPE) Provides Cardioprotection Via Succinate Oxidation Prior to Normothermic Perfusion in a Rat Model of Donation After Circulatory Death (DCD) American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Mar, 2021 | Pubmed ID: 32786170 How to Handle Arterial Conduits in Liver Transplantation? Evidence From the First Multicenter Risk Analysis Annals of Surgery. Dec, 2021 | Pubmed ID: 31972653 Hyperoxia in Portal Vein Causes Enhanced Vasoconstriction in Arterial Vascular Bed Scientific Reports. Dec, 2020 | Pubmed ID: 33262362 Reply To: Lactate Measurements in an Integrated Perfusion Machine for Human Livers Nature Biotechnology. Nov, 2020 | Pubmed ID: 33106684 Hypothermic Oxygenated Perfusion Protects from Mitochondrial Injury Before Liver Transplantation EBioMedicine. Oct, 2020 | Pubmed ID: 32979838 Hypothermic Oxygenated Liver Perfusion (HOPE) Prevents Tumor Recurrence in Liver Transplantation From Donation After Circulatory Death Annals of Surgery. 11, 2020 | Pubmed ID: 32889870 Choices of Therapeutic Strategies for Colorectal Liver Metastases Among Expert Liver Surgeons: A Throw of the Dice? Annals of Surgery. Nov, 2020 | Pubmed ID: 32833764 Hypothermic Oxygenated Perfusion Versus Normothermic Regional Perfusion in Liver Transplantation From Controlled Donation After Circulatory Death: First International Comparative Study Annals of Surgery. Nov, 2020 | Pubmed ID: 32833758 Brief Bubble and Intermittent Surface Oxygenation Is a Simple and Effective Alternative for Membrane Oxygenation During Hypothermic Machine Perfusion in Kidneys Transplantation Direct. Jul, 2020 | Pubmed ID: 32766426 Modern Therapeutic Approaches for the Treatment of Malignant Liver tumours Nature Reviews. Gastroenterology & Hepatology. Dec, 2020 | Pubmed ID: 32681074 Should Kidney Allografts from Old Donors Be Allocated Only to Old Recipients? Transplant International : Official Journal of the European Society for Organ Transplantation. Aug, 2020 | Pubmed ID: 32337766 The Swiss Approach to the COVID-19 Outbreak American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Jul, 2020 | Pubmed ID: 32330352 Brief O Uploading During Continuous Hypothermic Machine Perfusion is Simple Yet Effective Oxygenation Method to Improve Initial Kidney Function in a Porcine Autotransplant Model American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Aug, 2020 | Pubmed ID: 32012434 An Integrated Perfusion Machine Preserves Injured Human Livers for 1 Week Nature Biotechnology. Feb, 2020 | Pubmed ID: 31932726 Machine Perfusion Strategies in Liver Transplantation Hepatobiliary Surgery and Nutrition. Oct, 2019 | Pubmed ID: 31673538 Portobiliary Fistula in a Liver Transplant Recipient Treated With an Endoscopically Deployed Fully Covered Self-Expandable Biliary Metal Stent ACG Case Reports Journal. May, 2019 | Pubmed ID: 31616750 Novel Real-time Prediction of Liver Graft Function During Hypothermic Oxygenated Machine Perfusion Before Liver Transplantation Annals of Surgery. Nov, 2019 | Pubmed ID: 31592808 Normothermic Regional Perfusion - What is the Benefit? Journal of Hepatology. Aug, 2019 | Pubmed ID: 31130440 Can Hypothermic Oxygenated Perfusion (HOPE) Rescue Futile DCD Liver Grafts? HPB : the Official Journal of the International Hepato Pancreato Biliary Association. Sep, 2019 | Pubmed ID: 30777695 Letter to Editor: Repair or Prevent: What Is the Real Impact of Normothermic Machine Perfusion in Liver Transplantation? Hepatology (Baltimore, Md.). Dec, 2019 | Pubmed ID: 30773663 Hypothermic Oxygenated Perfusion: A Simple and Effective Method to Modulate the Immune Response in Kidney Transplantation Transplantation. May, 2019 | Pubmed ID: 30747849 Outcomes of DCD Liver Transplantation Using Organs Treated by Hypothermic Oxygenated Perfusion Before Implantation Journal of Hepatology. Jan, 2019 | Pubmed ID: 30342115 Technical Aspects of Orthotopic Liver Transplantation-a Survey-Based Study Within the Eurotransplant, Swisstransplant, Scandiatransplant, and British Transplantation Society Networks Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract. 03, 2019 | Pubmed ID: 30097968 A Systematic Review and Meta-analysis of Rescue Revascularization with Arterial Conduits in Liver Transplantation American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Feb, 2019 | Pubmed ID: 29996000 Correction To: Hypothermic Machine Preservation of the Liver: State of the Art Current Transplantation Reports. 2018 | Pubmed ID: 31329796 Impact of Machine Perfusion on Biliary Complications After Liver Transplantation International Journal of Molecular Sciences. Nov, 2018 | Pubmed ID: 30424553 Reply to "Ex Situ Normothermic Machine Perfusion of Donor Livers Using a Haemoglobin-based Oxygen Carrier: a Viable Alternative to Red Blood Cells" Transplant International : Official Journal of the European Society for Organ Transplantation. Nov, 2018 | Pubmed ID: 30118554 Perfusion Settings and Additives in Liver Normothermic Machine Perfusion with Red Blood Cells As Oxygen Carrier. A Systematic Review of Human and Porcine Perfusion Protocols Transplant International : Official Journal of the European Society for Organ Transplantation. Jun, 2018 | Pubmed ID: 29928775 Identifying Risk Profiles in Liver Transplant Candidates and Implications for Induction Immunosuppression Transplantation Reviews (Orlando, Fla.). 07, 2018 | Pubmed ID: 29709248 Hypothermic Machine Preservation of the Liver: State of the Art Current Transplantation Reports. 2018 | Pubmed ID: 29564206 Hepatic Artery Occlusion in Liver Transplantation: What Counts More, the Type of Reconstruction or the Severity of the Recipient's Disease? Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Jun, 2018 | Pubmed ID: 29493895 Uploading Cellular Batteries: Caring for Mitochondria is Key Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Apr, 2018 | Pubmed ID: 29460371 The UK DCD Risk Score: A New Proposal to Define Futility in Donation-after-circulatory-death Liver Transplantation Journal of Hepatology. Mar, 2018 | Pubmed ID: 29155020 Potentially Inappropriate Liver Transplantation in the Era of the "sickest First" Policy - A Search for the Upper Limits Journal of Hepatology. Apr, 2018 | Pubmed ID: 29133246 Defining Benchmarks in Liver Transplantation: A Multicenter Outcome Analysis Determining Best Achievable Results Annals of Surgery. 03, 2018 | Pubmed ID: 28885508 Hypothermic Liver Perfusion Current Opinion in Organ Transplantation. Dec, 2017 | Pubmed ID: 28922301 Hypothermic Oxygenated Perfusion (HOPE) for Fatty Liver Grafts in Rats and Humans Journal of Hepatology. Sep, 2017 | Pubmed ID: 28870676 Advances in Hypothermic Perfusion Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Oct, 2017 | Pubmed ID: 28815993 Hypo- and Normothermic Perfusion of the Liver: Which Way to Go? Best Practice & Research. Clinical Gastroenterology. Apr, 2017 | Pubmed ID: 28624105 Can Immunosuppression Be Stopped After Liver Transplantation? The Lancet. Gastroenterology & Hepatology. Jul, 2017 | Pubmed ID: 28606879 Postoperative Delirium After Liver Transplantation is Associated With Increased Length of Stay and Lower Survival in a Prospective Cohort Progress in Transplantation (Aliso Viejo, Calif.). Mar, 2017 | Pubmed ID: 27899718 Defining MoRAL After Liver Transplantation Annals of Surgery. Mar, 2017 | Pubmed ID: 27759624 Reply to "Reducing Nonanastomotic Biliary Strictures in Donation After Circulatory Death Liver Transplantation: Cold Ischemia Matters" Annals of Surgery. Dec, 2017 | Pubmed ID: 27479132 Development of OXY111A, a Novel Hypoxia-modifier As a Potential Antitumor Agent in Patients with Hepato-pancreato-biliary Neoplasms - Protocol of a First Ib/IIa Clinical Trial BMC Cancer. Oct, 2016 | Pubmed ID: 27756258 Liver Retransplantation with Cavoportal Hemitransposition After Percutaneous Mesocaval Shunt Creation Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Aug, 2016 | Pubmed ID: 27096231 Hypothermic Machine Perfusion in Liver Transplantation Current Opinion in Organ Transplantation. Jun, 2016 | Pubmed ID: 26918882 Reply to 'Is Single Portal Vein Perfusion the Best Approach for Machine Preservation of Liver Grafts?' Journal of Hepatology. May, 2016 | Pubmed ID: 26845037 Is Single Portal Vein Approach Sufficient for Hypothermic Machine Perfusion of DCD Liver Grafts? Journal of Hepatology. Jan, 2016 | Pubmed ID: 26432684 First Comparison of Hypothermic Oxygenated PErfusion Versus Static Cold Storage of Human Donation After Cardiac Death Liver Transplants: An International-matched Case Analysis Annals of Surgery. Nov, 2015 | Pubmed ID: 26583664 Hepatocyte Transfection in Small Pigs After Weaning by Hydrodynamic Intraportal Injection of Naked DNA/Minicircle Vectors Human Gene Therapy Methods. Oct, 2015 | Pubmed ID: 26398117 Hypothermic Liver Perfusion Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Nov, 2015 | Pubmed ID: 26334767 Conditioning With Sevoflurane in Liver Transplantation: Results of a Multicenter Randomized Controlled Trial Transplantation. Aug, 2015 | Pubmed ID: 25769076 Reply To: "The Rescue of DCD Rodent Livers Grafts: is There HOPE?" Journal of Hepatology. Mar, 2015 | Pubmed ID: 25463540 Challenges to Liver Transplantation and Strategies to Improve Outcomes Gastroenterology. Feb, 2015 | Pubmed ID: 25224524 Role of Hypothermic Machine Perfusion in Liver Transplantation Transplant International : Official Journal of the European Society for Organ Transplantation. Jun, 2015 | Pubmed ID: 24852621 Hypothermic Oxygenated Perfusion (HOPE) Downregulates the Immune Response in a Rat Model of Liver Transplantation Annals of Surgery. Nov, 2014 | Pubmed ID: 25243553 Warm Vs. Cold Perfusion Techniques to Rescue Rodent Liver Grafts Journal of Hepatology. Dec, 2014 | Pubmed ID: 25086285 HOPE for Human Liver Grafts Obtained from Donors After Cardiac Death Journal of Hepatology. Apr, 2014 | Pubmed ID: 24295869 Novel Rescue Procedure for Inferior Vena Cava Reconstruction in Living-donor Liver Transplantation Using a Vascular Graft Recovered 25 H After Donors' Circulatory Death and Systematic Review Transplant International : Official Journal of the European Society for Organ Transplantation. Feb, 2014 | Pubmed ID: 24289717 Reply to Letter: "The Balance of Risk Score for Allocation in Liver Transplantation" Annals of Surgery. Feb, 2014 | Pubmed ID: 23877366 Successful Salvage Chemotherapy with FOLFIRINOX for Recurrent Mixed Acinar Cell Carcinoma and Ductal Adenocarcinoma of the Pancreas in an Adolescent Patient Case Reports in Oncology. 2013 | Pubmed ID: 24163668 Hypothermic Oxygenated Perfusion (HOPE) Protects from Biliary Injury in a Rodent Model of DCD Liver Transplantation Journal of Hepatology. Nov, 2013 | Pubmed ID: 23820408 Protective Mechanisms of End-ischemic Cold Machine Perfusion in DCD Liver Grafts Journal of Hepatology. Feb, 2013 | Pubmed ID: 23063573 The Use of Fatty Liver Grafts in Modern Allocation Systems: Risk Assessment by the Balance of Risk (BAR) Score Annals of Surgery. Nov, 2012 | Pubmed ID: 23095632 Liver Transplantation Because of Acute Liver Failure Due to Heme Arginate Overdose in a Patient with Acute Intermittent Porphyria Case Reports in Gastroenterology. Jan, 2012 | Pubmed ID: 22649331 Finding the Right Position: a Three-year, Single-center Experience with the "self-locating" Catheter Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis. 2010 | Pubmed ID: 20228177 Biological Modulation of Liver Ischemia-reperfusion Injury Current Opinion in Organ Transplantation. Apr, 2010 | Pubmed ID: 20125019 Current and Future Trends in Liver Transplantation in Europe Gastroenterology. Mar, 2010 | Pubmed ID: 20096694 One Hour Hypothermic Oxygenated Perfusion (HOPE) Protects Nonviable Liver Allografts Donated After Cardiac Death Annals of Surgery. Nov, 2009 | Pubmed ID: 19806056 Abdominal Drains in Liver Transplantation: Useful Tool or Useless Dogma? A Matched Case-control Study Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. Jan, 2009 | Pubmed ID: 19109839 Novel Short-term Hypothermic Oxygenated Perfusion (HOPE) System Prevents Injury in Rat Liver Graft from Non-heart Beating Donor Annals of Surgery. Dec, 2006 | Pubmed ID: 17122622 Rescue of the Cold Preserved Rat Liver by Hypothermic Oxygenated Machine Perfusion American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. May, 2006 | Pubmed ID: 16611326 Approche chirurgicale, défis et résolutions pour la transplantation utérine chez le rat Keyue Sun1, Daniela Bochicchio1, Pierre-Alain Clavien1, Philipp Dutkowski1, Bostjan Humar1 1Swiss HPB Laboratory, Department of Visceral & Transplant Surgery, University Hospital Zürich JoVE 64757 Medicina
Approche chirurgicale, défis et résolutions pour la transplantation utérine chez le rat Keyue Sun1, Daniela Bochicchio1, Pierre-Alain Clavien1, Philipp Dutkowski1, Bostjan Humar1 1Swiss HPB Laboratory, Department of Visceral & Transplant Surgery, University Hospital Zürich JoVE 64757 Medicina