Ranjan Dutta Department of Neurosciences, Lerner Research Institute Cleveland Clinic Biography Publications Institution JoVE Articles Ranjan Dutta has not added a biography. If you are Ranjan Dutta and would like to personalize this page please email our Author Liaison for assistance. Publications PHERV-W Envelope Protein Fuels Microglial Cell-dependent Damage of Myelinated Axons in Multiple Sclerosis Proceedings of the National Academy of Sciences of the United States of America. Jun, 2019 | Pubmed ID: 31213545 Expression of Disease-related MiRNAs in White-matter Lesions of Progressive Multiple Sclerosis Brains Annals of Clinical and Translational Neurology. May, 2019 | Pubmed ID: 31139683 Proteomic Approaches to Decipher Mechanisms Underlying Pathogenesis in Multiple Sclerosis Patients Proteomics. May, 2019 | Pubmed ID: 31119864 Constitutional Mislocalization of Pten Drives Precocious Maturation in Oligodendrocytes and Aberrant Myelination in Model of Autism Spectrum Disorder Translational Psychiatry. 01, 2019 | Pubmed ID: 30664625 Current Advancements in Promoting Remyelination in Multiple Sclerosis Multiple Sclerosis (Houndmills, Basingstoke, England). 01, 2019 | Pubmed ID: 30270725 CK2 Inhibition Confers Functional Protection to Young and Aging Axons Against Ischemia by Differentially Regulating the CDK5 and AKT Signaling Pathways Neurobiology of Disease. 06, 2019 | Pubmed ID: 29944965 Distinct Gene Profiles of Bone Marrow-Derived Macrophages and Microglia During Neurotropic Coronavirus-Induced Demyelination Frontiers in Immunology. 2018 | Pubmed ID: 29942315 Much, if Not All, of the Cortical Damage in MS Can Be Attributed to the Microglial Cell - No Multiple Sclerosis (Houndmills, Basingstoke, England). 06, 2018 | Pubmed ID: 29754529 Alterations in CA1 Hippocampal Synapses in a Mouse Model of Fragile X Syndrome Glia. 04, 2018 | Pubmed ID: 29274095 A Mouse Model for Testing Remyelinating Therapies Experimental Neurology. 09, 2016 | Pubmed ID: 27384502 Promoting Remyelination in Multiple Sclerosis: Current Drugs and Future Prospects Multiple Sclerosis (Houndmills, Basingstoke, England). Apr, 2015 | Pubmed ID: 25623245 Microglial Displacement of Inhibitory Synapses Provides Neuroprotection in the Adult Brain Nature Communications. 2014 | Pubmed ID: 25047355 Relapsing and Progressive Forms of Multiple Sclerosis: Insights from Pathology Current Opinion in Neurology. Jun, 2014 | Pubmed ID: 24722325 Axonal Loss in Multiple Sclerosis: Causes and Mechanisms Handbook of Clinical Neurology. 2014 | Pubmed ID: 24507515 Epigenome-wide Differences in Pathology-free Regions of Multiple Sclerosis-affected Brains Nature Neuroscience. Jan, 2014 | Pubmed ID: 24270187 Gene Expression Changes Underlying Cortical Pathology: Clues to Understanding Neurological Disability in Multiple Sclerosis Multiple Sclerosis (Houndmills, Basingstoke, England). Sep, 2013 | Pubmed ID: 23996595 Activated Microglia Enhance Neurogenesis Via Trypsinogen Secretion Proceedings of the National Academy of Sciences of the United States of America. May, 2013 | Pubmed ID: 23650361 Hippocampal Demyelination and Memory Dysfunction Are Associated with Increased Levels of the Neuronal MicroRNA MiR-124 and Reduced AMPA Receptors Annals of Neurology. May, 2013 | Pubmed ID: 23595422 Cortical Remyelination: a New Target for Repair Therapies in Multiple Sclerosis Annals of Neurology. Dec, 2012 | Pubmed ID: 23076662 Lipopolysaccharide-induced Microglial Activation and Neuroprotection Against Experimental Brain Injury is Independent of Hematogenous TLR4 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2012 | Pubmed ID: 22915113 Gene Expression Profiling in Multiple Sclerosis Brain Neurobiology of Disease. Jan, 2012 | Pubmed ID: 21147224 Demyelination Causes Synaptic Alterations in Hippocampi from Multiple Sclerosis Patients Annals of Neurology. Mar, 2011 | Pubmed ID: 21446020 Mechanisms of Neuronal Dysfunction and Degeneration in Multiple Sclerosis Progress in Neurobiology. Jan, 2011 | Pubmed ID: 20946934 Activation of the Ciliary Neurotrophic Factor (CNTF) Signalling Pathway in Cortical Neurons of Multiple Sclerosis Patients Brain : a Journal of Neurology. Oct, 2007 | Pubmed ID: 17898009 Pathogenesis of Axonal and Neuronal Damage in Multiple Sclerosis Neurology. May, 2007 | Pubmed ID: 17548565 [Pathology and Definition of Multiple Sclerosis] La Revue Du Praticien. Jun, 2006 | Pubmed ID: 16948216 Mitochondrial Dysfunction As a Cause of Axonal Degeneration in Multiple Sclerosis Patients Annals of Neurology. Mar, 2006 | Pubmed ID: 16392116 Dysmyelinated Lower Motor Neurons Retract and Regenerate Dysfunctional Synaptic Terminals The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2004 | Pubmed ID: 15084670 Comprehensive Autopsy Program for Individuals with Multiple Sclerosis Ranjan Dutta*1, Kedar R. Mahajan*1,3, Kunio Nakamura*3, Daniel Ontaneda*2, Jacqueline Chen1, Christina Volsko1, Jessica Dudman1, Emilie Christie1, Jordon Dunham1, Robert J. Fox3, Bruce D. Trapp1 1Department of Neurosciences, Lerner Research Institute, Cleveland Clinic, 2Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, 3Mellen Center for Treatment and Research in Multiple Sclerosis, Neurological Institute, Cleveland Clinic JoVE 59511 Neurociência
Comprehensive Autopsy Program for Individuals with Multiple Sclerosis Ranjan Dutta*1, Kedar R. Mahajan*1,3, Kunio Nakamura*3, Daniel Ontaneda*2, Jacqueline Chen1, Christina Volsko1, Jessica Dudman1, Emilie Christie1, Jordon Dunham1, Robert J. Fox3, Bruce D. Trapp1 1Department of Neurosciences, Lerner Research Institute, Cleveland Clinic, 2Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, 3Mellen Center for Treatment and Research in Multiple Sclerosis, Neurological Institute, Cleveland Clinic JoVE 59511 Neurociência