Richard L. Leask Chemical Engineering McGill University Biography Publications Institution JoVE Articles Richard L. Leask has not added a biography. If you are Richard L. Leask and would like to personalize this page please email our Author Liaison for assistance. Publications Statin Therapy Influences Endothelial Cell Morphology and F-actin Cytoskeleton Structure when Exposed to Static and Laminar Shear Stress Conditions Life Sciences. May, 2013 | Pubmed ID: 23517776 Designing Green Plasticizers: Influence of Alkyl Chain Length on Biodegradation and Plasticization Properties of Succinate Based Plasticizers Chemosphere. Apr, 2013 | Pubmed ID: 23340052 Use of Inert Gas Jets to Measure the Forces Required for Mechanical Gene Transfection Biomedical Engineering Online. 2012 | Pubmed ID: 22963645 Regional Variations in Canine Descending Aortic Tissue Mechanical Properties Change with Formalin Fixation Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology. Sep-Oct, 2012 | Pubmed ID: 22300500 Effects of Di-(2-ethylhexyl) Phthalate and Four of Its Metabolites on Steroidogenesis in MA-10 Cells Ecotoxicology and Environmental Safety. May, 2012 | Pubmed ID: 22236953 Differential Response of Endothelial Cells to Simvastatin when Conditioned with Steady, Non-reversing Pulsatile or Oscillating Shear Stress Annals of Biomedical Engineering. Jan, 2011 | Pubmed ID: 20737288 Laminar Shear Stress Prevents Simvastatin-induced Adhesion Molecule Expression in Cytokine Activated Endothelial Cells European Journal of Pharmacology. Dec, 2010 | Pubmed ID: 20863785 Endothelial Cell Morphologic Response to Asymmetric Stenosis Hemodynamics: Effects of Spatial Wall Shear Stress Gradients Journal of Biomechanical Engineering. Aug, 2010 | Pubmed ID: 20670062 The Response of Human Aortic Endothelial Cells in a Stenotic Hemodynamic Environment: Effect of Duration, Magnitude, and Spatial Gradients in Wall Shear Stress Journal of Biomechanical Engineering. Jul, 2010 | Pubmed ID: 20590293 Effect of Simvastatin on Kruppel-like Factor2, Endothelial Nitric Oxide Synthase and Thrombomodulin Expression in Endothelial Cells Under Shear Stress Life Sciences. Jul, 2010 | Pubmed ID: 20493886 Regional Dependency of the Vascular Smooth Muscle Cell Contribution to the Mechanical Properties of the Pig Ascending Aortic Tissue Journal of Biomechanics. Aug, 2010 | Pubmed ID: 20478560 Neutrophil Adhesion on Endothelial Cells in a Novel Asymmetric Stenosis Model: Effect of Wall Shear Stress Gradients Annals of Biomedical Engineering. Sep, 2010 | Pubmed ID: 20387119 Concentration and Time Effects of Dextran Exposure on Endothelial Cell Viability, Attachment, and Inflammatory Marker Expression in Vitro Annals of Biomedical Engineering. Apr, 2010 | Pubmed ID: 20108164 Second Harmonic Generation Microscopy to Investigate Collagen Configuration: a Pericarditis Case Study Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology. Jul-Aug, 2010 | Pubmed ID: 19632137 The Development of 3-D, in Vitro, Endothelial Culture Models for the Study of Coronary Artery Disease Biomedical Engineering Online. 2009 | Pubmed ID: 19863806 A Comparison of Mechanical Properties of Materials Used in Aortic Arch Reconstruction The Annals of Thoracic Surgery. Nov, 2009 | Pubmed ID: 19853098 Local Mechanical and Structural Properties of Healthy and Diseased Human Ascending Aorta Tissue Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology. Mar-Apr, 2009 | Pubmed ID: 18402840 Impact of Degradation Products of Sulfamethoxazole on Mammalian Cultured Cells Environmental Toxicology. Aug, 2008 | Pubmed ID: 18247415 Time-dependent 3D Simulations of the Hemodynamics in a Stented Coronary Artery Biomedical Materials (Bristol, England). Mar, 2007 | Pubmed ID: 18458417 Mechanical Properties and Microscopic Findings of a Dacron Graft Explanted 27 Years After Coarctation Repair The Journal of Thoracic and Cardiovascular Surgery. Dec, 2007 | Pubmed ID: 18023686 Effects of Diffusion Coefficients and Struts Apposition Using Numerical Simulations for Drug Eluting Coronary Stents Journal of Biomechanical Engineering. Oct, 2007 | Pubmed ID: 17887899 Pathologic Analysis of 19 Heart Valves with Silver-coated Sewing Rings Journal of Cardiac Surgery. Nov-Dec, 2006 | Pubmed ID: 17073948 Morphological Findings in 192 Surgically Excised Native Mitral Valves The Canadian Journal of Cardiology. Oct, 2006 | Pubmed ID: 17036100 Normal Wound Healing in Mice Deficient for Fibulin-5, an Elastin Binding Protein Essential for Dermal Elastic Fiber Assembly The Journal of Investigative Dermatology. Dec, 2006 | Pubmed ID: 16902421 Invited Commentary The Annals of Thoracic Surgery. Mar, 2006 | Pubmed ID: 16488696 Morphological Findings in Explanted Toronto Stentless Porcine Valves Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology. Jan-Feb, 2006 | Pubmed ID: 16414456 Image Based Biomechanics of Coronary Plaque Studies in Health Technology and Informatics. 2005 | Pubmed ID: 15923740 Human Saphenous Vein Coronary Artery Bypass Graft Morphology, Geometry and Hemodynamics Annals of Biomedical Engineering. Mar, 2005 | Pubmed ID: 15868720 Artificial Chordae Tendinae: Long-term Changes Journal of Cardiac Surgery. Jan-Feb, 2005 | Pubmed ID: 15673420 Intimal Thickness is Not Associated with Wall Shear Stress Patterns in the Human Right Coronary Artery Arteriosclerosis, Thrombosis, and Vascular Biology. Dec, 2004 | Pubmed ID: 15472129 Hemodynamic Effects of Clot Entrapment in the TrapEase Inferior Vena Cava Filter Journal of Vascular and Interventional Radiology : JVIR. May, 2004 | Pubmed ID: 15126659 The Relationship Between Wall Shear Stress Distributions and Intimal Thickening in the Human Abdominal Aorta Biomedical Engineering Online. Nov, 2003 | Pubmed ID: 14641919 Mechanical Heart Valve Prostheses: Identification and Evaluation (erratum) Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology. Nov-Dec, 2003 | Pubmed ID: 14630298 Primary Cardiac Sarcoma Involving the Pulmonary Artery and Valve The Canadian Journal of Cardiology. Jun, 2003 | Pubmed ID: 12813618 Biological Replacement Heart Valves. Identification and Evaluation Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology. May-Jun, 2003 | Pubmed ID: 12763552 Host Tissue Overgrowth in a Mitral Valve Conserving Procedure Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology. Mar-Apr, 2003 | Pubmed ID: 12684164 Stentless Porcine Valves: New Mode of Failure The Canadian Journal of Cardiology. Feb, 2003 | Pubmed ID: 12601444 Mechanical Heart Valve Prostheses: Identification and Evaluation Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology. Jan-Feb, 2003 | Pubmed ID: 12598013 Endothelium and Valvular Diseases of the Heart Microscopy Research and Technique. Feb, 2003 | Pubmed ID: 12539167 Genetic Abnormalities of the Endothelium Microscopy Research and Technique. Jan, 2003 | Pubmed ID: 12500258 Pulmonary Site Porcine Bioprosthesis: Evaluation at 14 Years The Canadian Journal of Cardiology. Nov, 2002 | Pubmed ID: 12464980 Images in Cardiovascular Medicine. Pulmonary Site Bioprosthesis: Failure at 15 Years Circulation. Aug, 2002 | Pubmed ID: 12196349 Clinical and Pathophysiological Implications of a Bicuspid Aortic Valve Circulation. Aug, 2002 | Pubmed ID: 12186790 Chronic Aortic Dissection: 27 Years After Aortic Valve Replacement The Canadian Journal of Cardiology. Apr, 2002 | Pubmed ID: 11992139 Bir atıl gaz püskürtüsünün kullanılması Uygulanan Hücrelerinin Permeabilization Scott Cooper1, Paul Jonak1, Guillaume Chouinard-Pelletier1, Sylvain Coulombe1, Elizabeth Jones1, Richard L. Leask1,2 1Chemical Engineering, McGill University, 2Montreal Heart Institute JoVE 50612 Bioengenharia
Bir atıl gaz püskürtüsünün kullanılması Uygulanan Hücrelerinin Permeabilization Scott Cooper1, Paul Jonak1, Guillaume Chouinard-Pelletier1, Sylvain Coulombe1, Elizabeth Jones1, Richard L. Leask1,2 1Chemical Engineering, McGill University, 2Montreal Heart Institute JoVE 50612 Bioengenharia