Satoshi H. Namekawa Division of Reproductive Sciences, Division of Developmental Biology, Perinatal Institute Cincinnati Children's Hospital Medical Center Biography Publications Institution JoVE Articles Satoshi H. Namekawa has not added a biography. If you are Satoshi H. Namekawa and would like to personalize this page please email our Author Liaison for assistance. Publications Super-enhancer Switching Drives a Burst in Gene Expression at the Mitosis-to-meiosis Transition Nature Structural & Molecular Biology. 10, 2020 | Pubmed ID: 32895557 Endogenous Retroviruses Drive Species-specific Germline Transcriptomes in Mammals Nature Structural & Molecular Biology. 10, 2020 | Pubmed ID: 32895553 Licensing Meiotic Progression† Biology of Reproduction. 06, 2020 | Pubmed ID: 32338765 FANCD2 is Required for the Repression of Germline Transposable Elements Reproduction (Cambridge, England). 06, 2020 | Pubmed ID: 32163912 BRUCE Preserves Genomic Stability in the Male Germline of Mice Cell Death and Differentiation. Aug, 2020 | Pubmed ID: 32139899 The Initiation of Meiotic Sex Chromosome Inactivation Sequesters DNA Damage Signaling from Autosomes in Mouse Spermatogenesis Current Biology : CB. 02, 2020 | Pubmed ID: 31902729 UHRF1 Suppresses Retrotransposons and Cooperates with PRMT5 and PIWI Proteins in Male Germ Cells Nature Communications. 10, 2019 | Pubmed ID: 31624244 Attenuated Chromatin Compartmentalization in Meiosis and Its Maturation in Sperm Development Nature Structural & Molecular Biology. 03, 2019 | Pubmed ID: 30778237 XY Oocytes of Sex-reversed Females with a Sry Mutation Deviate from the Normal Developmental Process Beyond the Mitotic Stage† Biology of Reproduction. 03, 2019 | Pubmed ID: 30289439 A Rapidly Evolved Domain, the SCML2 DNA-binding Repeats, Contributes to Chromatin Binding of Mouse SCML2† Biology of Reproduction. 02, 2019 | Pubmed ID: 30137219 Chromosome Spread Analyses of Meiotic Sex Chromosome Inactivation Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 30218364 SCML2 Promotes Heterochromatin Organization in Late Spermatogenesis Journal of Cell Science. 09, 2018 | Pubmed ID: 30097555 Epigenomic and Single-cell Profiling of Human Spermatogonial Stem Cells Stem Cell Investigation. 2018 | Pubmed ID: 29782571 Polycomb Protein SCML2 Facilitates H3K27me3 to Establish Bivalent Domains in the Male Germline Proceedings of the National Academy of Sciences of the United States of America. 05, 2018 | Pubmed ID: 29686098 RNF8 and SCML2 Cooperate to Regulate Ubiquitination and H3K27 Acetylation for Escape Gene Activation on the Sex Chromosomes PLoS Genetics. 02, 2018 | Pubmed ID: 29462142 CHEK1 Coordinates DNA Damage Signaling and Meiotic Progression in the Male Germline of Mice Human Molecular Genetics. 04, 2018 | Pubmed ID: 29360988 Dynamic Reorganization of Open Chromatin Underlies Diverse Transcriptomes During Spermatogenesis Nucleic Acids Research. 01, 2018 | Pubmed ID: 29126117 Polycomb Directs Timely Activation of Germline Genes in Spermatogenesis Genes & Development. 08, 2017 | Pubmed ID: 28924034 Fancd2 in Vivo Interaction Network Reveals a Non-canonical Role in Mitochondrial Function Scientific Reports. 04, 2017 | Pubmed ID: 28378742 Elucidation of the Fanconi Anemia Protein Network in Meiosis and Its Function in the Regulation of Histone Modifications Cell Reports. 10, 2016 | Pubmed ID: 27760317 Fancb Deficiency Impairs Hematopoietic Stem Cell Function Scientific Reports. Dec, 2015 | Pubmed ID: 26658157 Poised Chromatin and Bivalent Domains Facilitate the Mitosis-to-meiosis Transition in the Male Germline BMC Biology. Jul, 2015 | Pubmed ID: 26198001 FANCB is Essential in the Male Germline and Regulates H3K9 Methylation on the Sex Chromosomes During Meiosis Human Molecular Genetics. Sep, 2015 | Pubmed ID: 26123487 BAZ1B is Dispensable for H2AX Phosphorylation on Tyrosine 142 During Spermatogenesis Biology Open. May, 2015 | Pubmed ID: 25979708 Functional Significance of the Sex Chromosomes During Spermatogenesis Reproduction (Cambridge, England). Jun, 2015 | Pubmed ID: 25948089 Loss of Faap20 Causes Hematopoietic Stem and Progenitor Cell Depletion in Mice Under Genotoxic Stress Stem Cells (Dayton, Ohio). Jul, 2015 | Pubmed ID: 25917546 SCML2 Establishes the Male Germline Epigenome Through Regulation of Histone H2A Ubiquitination Developmental Cell. Mar, 2015 | Pubmed ID: 25703348 BRCA1 Establishes DNA Damage Signaling and Pericentric Heterochromatin of the X Chromosome in Male Meiosis The Journal of Cell Biology. Jun, 2014 | Pubmed ID: 24914237 MEK/ERK Signaling Directly and Indirectly Contributes to the Cyclical Self-renewal of Spermatogonial Stem Cells Stem Cells (Dayton, Ohio). Nov, 2013 | Pubmed ID: 23897718 The Great Escape: Active Genes on Inactive Sex Chromosomes and Their Evolutionary Implications Epigenetics : Official Journal of the DNA Methylation Society. Sep, 2013 | Pubmed ID: 23880818 RNF8 Regulates Active Epigenetic Modifications and Escape Gene Activation from Inactive Sex Chromosomes in Post-meiotic Spermatids Genes & Development. Dec, 2012 | Pubmed ID: 23249736 The RNase III Enzyme DROSHA is Essential for MicroRNA Production and Spermatogenesis The Journal of Biological Chemistry. Jul, 2012 | Pubmed ID: 22665486 Sex Chromosome Inactivation in Germ Cells: Emerging Roles of DNA Damage Response Pathways Cellular and Molecular Life Sciences : CMLS. Aug, 2012 | Pubmed ID: 22382926 Human Postmeiotic Sex Chromatin and Its Impact on Sex Chromosome Evolution Genome Research. May, 2012 | Pubmed ID: 22375025 X-inactivation and X-reactivation: Epigenetic Hallmarks of Mammalian Reproduction and Pluripotent Stem Cells Human Genetics. Aug, 2011 | Pubmed ID: 21667284 MDC1 Directs Chromosome-wide Silencing of the Sex Chromosomes in Male Germ Cells Genes & Development. May, 2011 | Pubmed ID: 21536735 Detection of Nascent RNA, Single-copy DNA and Protein Localization by ImmunoFISH in Mouse Germ Cells and Preimplantation Embryos Nature Protocols. Mar, 2011 | Pubmed ID: 21372809 Mice Lacking Alkbh1 Display Sex-ratio Distortion and Unilateral Eye Defects PloS One. 2010 | Pubmed ID: 21072209 Two-step Imprinted X Inactivation: Repeat Versus Genic Silencing in the Mouse Molecular and Cellular Biology. Jul, 2010 | Pubmed ID: 20404085 XY and ZW: is Meiotic Sex Chromosome Inactivation the Rule in Evolution? PLoS Genetics. May, 2009 | Pubmed ID: 19461890 Telomeric RNAs Mark Sex Chromosomes in Stem Cells Genetics. Jul, 2009 | Pubmed ID: 19380904 Coprinus Cinereus Mer3 is Required for Synaptonemal Complex Formation During Meiosis Chromosoma. Feb, 2009 | Pubmed ID: 18841377 Interaction Between Lim15/Dmc1 and the Homologue of the Large Subunit of CAF-1: a Molecular Link Between Recombination and Chromatin Assembly During Meiosis The FEBS Journal. May, 2008 | Pubmed ID: 18355319 Sex Chromosome Silencing in the Marsupial Male Germ Line Proceedings of the National Academy of Sciences of the United States of America. Jun, 2007 | Pubmed ID: 17535928 A Mammal-specific Doublesex Homolog Associates with Male Sex Chromatin and is Required for Male Meiosis PLoS Genetics. Apr, 2007 | Pubmed ID: 17447844 Proliferating Cell Nuclear Antigen (PCNA) Interacts with a Meiosis-specific RecA Homologues, Lim15/Dmc1, but Does Not Stimulate Its Strand Transfer Activity Biochemical and Biophysical Research Communications. Jan, 2007 | Pubmed ID: 17157821 Sumoylation of a Meiosis-specific RecA Homolog, Lim15/Dmc1, Via Interaction with the Small Ubiquitin-related Modifier (SUMO)-conjugating Enzyme Ubc9 The FEBS Journal. Sep, 2006 | Pubmed ID: 16879611 Postmeiotic Sex Chromatin in the Male Germline of Mice Current Biology : CB. Apr, 2006 | Pubmed ID: 16581510 Knockdown of LIM15/DMC1 in the Mushroom Coprinus Cinereus by Double-stranded RNA-mediated Gene Silencing Microbiology (Reading, England). Nov, 2005 | Pubmed ID: 16272388 DNA Topoisomerase II Interacts with Lim15/Dmc1 in Meiosis Nucleic Acids Research. 2005 | Pubmed ID: 16221977 [Latest Frontiers of Meiosis Research in Coprinus Cinereus] Seikagaku. The Journal of Japanese Biochemical Society. Nov, 2004 | Pubmed ID: 15626033 Expression of Flap Endonuclease-1 During Meiosis in a Basidiomycete, Coprinus Cinereus Fungal Genetics and Biology : FG & B. May, 2004 | Pubmed ID: 15050538 Isolamento de células spermatogênicas murinas usando um corante de ligação de DNA permeável celular-permeável violeta Yu-Han Yeh*1,2, Mengwen Hu*1,2, Toshinori Nakagawa3,4, Akihiko Sakashita1,2, Shosei Yoshida3,4, So Maezawa5,6, Satoshi H. Namekawa1,2 1Division of Reproductive Sciences, Division of Developmental Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, 2Department of Pediatrics, University of Cincinnati College of Medicine, 3Division of Germ Cell Biology, National Institute for Basic Biology, National Institutes of Natural Sciences, 4Department of Basic Biology, School of Life Science, Graduate University for Advanced Studies (Sokendai), 5Department of Animal Science and Biotechnology, School of Veterinary Medicine, Azabu University, 6Faculty of Science and Technology, Department of Applied Biological Science, Tokyo University of Science JoVE 61666 Biologia do Desenvolvimento Método de preparação de slides para preservar arquitetura de cromatina tridimensional de células germinativas testiculares Satoshi H. Namekawa1,2 1Division of Reproductive Sciences, Division of Developmental Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, 2Department of Pediatrics, University of Cincinnati College of Medicine JoVE 50819 Biologia
Isolamento de células spermatogênicas murinas usando um corante de ligação de DNA permeável celular-permeável violeta Yu-Han Yeh*1,2, Mengwen Hu*1,2, Toshinori Nakagawa3,4, Akihiko Sakashita1,2, Shosei Yoshida3,4, So Maezawa5,6, Satoshi H. Namekawa1,2 1Division of Reproductive Sciences, Division of Developmental Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, 2Department of Pediatrics, University of Cincinnati College of Medicine, 3Division of Germ Cell Biology, National Institute for Basic Biology, National Institutes of Natural Sciences, 4Department of Basic Biology, School of Life Science, Graduate University for Advanced Studies (Sokendai), 5Department of Animal Science and Biotechnology, School of Veterinary Medicine, Azabu University, 6Faculty of Science and Technology, Department of Applied Biological Science, Tokyo University of Science JoVE 61666 Biologia do Desenvolvimento
Método de preparação de slides para preservar arquitetura de cromatina tridimensional de células germinativas testiculares Satoshi H. Namekawa1,2 1Division of Reproductive Sciences, Division of Developmental Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, 2Department of Pediatrics, University of Cincinnati College of Medicine JoVE 50819 Biologia