Serena Mazzucchelli Dipartimento di Scienze Biomediche e Cliniche “L. Sacco” Università di Milano Biography Publications Institution JoVE Articles Serena Mazzucchelli has not added a biography. If you are Serena Mazzucchelli and would like to personalize this page please email our Author Liaison for assistance. Publications Tumor Accumulation and Off-Target Biodistribution of an Indocyanine-Green Fluorescent Nanotracer: An Ex Vivo Study on an Orthotopic Murine Model of Breast Cancer International Journal of Molecular Sciences. Feb, 2021 | Pubmed ID: 33562574 Selective Targeting of Cancer-Associated Fibroblasts by Engineered H-Ferritin Nanocages Loaded with Navitoclax Cells. Feb, 2021 | Pubmed ID: 33562504 Combined Method to Remove Endotoxins from Protein Nanocages for Drug Delivery Applications: The Case of Human Ferritin Pharmaceutics. Feb, 2021 | Pubmed ID: 33562060 Development and Validation of a Simple and Versatile Method for the Quantification of Everolimus Loaded in H-ferritin Nanocages Using UHPLC-MS/MS Journal of Pharmaceutical and Biomedical Analysis. Nov, 2020 | Pubmed ID: 32987250 Indocyanine Green Nanoparticles: Are They Compelling for Cancer Treatment? Frontiers in Chemistry. 2020 | Pubmed ID: 32766203 Co-administration of H-ferritin-doxorubicin and Trastuzumab in Neoadjuvant Setting Improves Efficacy and Prevents Cardiotoxicity in HER2 + murine Breast Cancer Model Scientific Reports. 07, 2020 | Pubmed ID: 32651443 Everolimus Nanoformulation in Biological Nanoparticles Increases Drug Responsiveness in Resistant and Low-Responsive Breast Cancer Cell Lines Pharmaceutics. Aug, 2019 | Pubmed ID: 31382388 Nano-Strategies to Target Breast Cancer-Associated Fibroblasts: Rearranging the Tumor Microenvironment to Achieve Antitumor Efficacy International Journal of Molecular Sciences. Mar, 2019 | Pubmed ID: 30871158 Half-Chain Cetuximab Nanoconjugates Allow Multitarget Therapy of Triple Negative Breast Cancer Bioconjugate Chemistry. 11, 2018 | Pubmed ID: 30350574 Tumour Homing and Therapeutic Effect of Colloidal Nanoparticles Depend on the Number of Attached Antibodies Nature Communications. 12, 2016 | Pubmed ID: 27991503 Oral Delivery of Insulin Via Polyethylene Imine-based Nanoparticles for Colonic Release Allows Glycemic Control in Diabetic Rats Pharmacological Research. Aug, 2016 | Pubmed ID: 27181095 Ferritin Nanocages: A Biological Platform for Drug Delivery, Imaging and Theranostics in Cancer Pharmacological Research. May, 2016 | Pubmed ID: 26968122 The Potential of Protein-based Nanocages for Imaging and Drug Delivery Therapeutic Delivery. 2016 | Pubmed ID: 26893245 Nanoformulation of Antiretroviral Drugs Enhances Their Penetration Across the Blood Brain Barrier in Mice Nanomedicine : Nanotechnology, Biology, and Medicine. Aug, 2015 | Pubmed ID: 25839392 Peptide-nanoparticle Ligation Mediated by Cutinase Fusion for the Development of Cancer Cell-targeted Nanoconjugates Bioconjugate Chemistry. Apr, 2015 | Pubmed ID: 25741889 Protein Nanocages for Self-triggered Nuclear Delivery of DNA-targeted Chemotherapeutics in Cancer Cells Journal of Controlled Release : Official Journal of the Controlled Release Society. Dec, 2014 | Pubmed ID: 25312541 Development of U11-functionalized Gold Nanoparticles for Selective Targeting of Urokinase Plasminogen Activator Receptor-positive Breast Cancer Cells Bioconjugate Chemistry. Aug, 2014 | Pubmed ID: 25080049 Antiproliferative Effect of ASC-J9 Delivered by PLGA Nanoparticles Against Estrogen-dependent Breast Cancer Cells Molecular Pharmaceutics. Aug, 2014 | Pubmed ID: 24945469 Interactions of Ataxin-3 with Its Molecular Partners in the Protein Machinery That Sorts Protein Aggregates to the Aggresome The International Journal of Biochemistry & Cell Biology. Jun, 2014 | Pubmed ID: 24685680 Delivering Colloidal Nanoparticles to Mammalian Cells: a Nano-bio Interface Perspective Advanced Healthcare Materials. Jul, 2014 | Pubmed ID: 24443410 Dependence of Nanoparticle-cell Recognition Efficiency on the Surface Orientation of ScFv Targeting Ligands Biomaterials Science. Jul, 2013 | Pubmed ID: 32481827 Assessing the in Vivo Targeting Efficiency of Multifunctional Nanoconstructs Bearing Antibody-derived Ligands ACS Nano. Jul, 2013 | Pubmed ID: 23758591 Orientation-controlled Conjugation of Haloalkane Dehalogenase Fused Homing Peptides to Multifunctional Nanoparticles for the Specific Recognition of Cancer Cells Angewandte Chemie (International Ed. in English). Mar, 2013 | Pubmed ID: 23386453 Protein-assisted One-pot Synthesis and Biofunctionalization of Spherical Gold Nanoparticles for Selective Targeting of Cancer Cells Angewandte Chemie (International Ed. in English). Sep, 2012 | Pubmed ID: 22833476 Protein Oriented Ligation on Nanoparticles Exploiting O6-alkylguanine-DNA Transferase (SNAP) Genetically Encoded Fusion Small (Weinheim an Der Bergstrasse, Germany). May, 2012 | Pubmed ID: 22431243 Site-specific Conjugation of ScFvs Antibodies to Nanoparticles by Bioorthogonal Strain-promoted Alkyne-nitrone Cycloaddition Angewandte Chemie (International Ed. in English). Jan, 2012 | Pubmed ID: 22121095 Multiple Presentation of Scfv800E6 on Silica Nanospheres Enhances Targeting Efficiency Toward HER-2 Receptor in Breast Cancer Cells Bioconjugate Chemistry. Nov, 2011 | Pubmed ID: 22010849 HER2 Expression in Breast Cancer Cells is Downregulated Upon Active Targeting by Antibody-engineered Multifunctional Nanoparticles in Mice ACS Nano. Aug, 2011 | Pubmed ID: 21790185 Highly Efficient Production of Anti-HER2 ScFv Antibody Variant for Targeting Breast Cancer Cells Applied Microbiology and Biotechnology. Aug, 2011 | Pubmed ID: 21538107 Investigating the Structural Biofunctionality of Antibodies Conjugated to Magnetic Nanoparticles Nanoscale. Feb, 2011 | Pubmed ID: 20877896 Single-domain Protein A-engineered Magnetic Nanoparticles: Toward a Universal Strategy to Site-specific Labeling of Antibodies for Targeted Detection of Tumor Cells ACS Nano. Oct, 2010 | Pubmed ID: 20825223 HER2 Targeting As a Two-sided Strategy for Breast Cancer Diagnosis and Treatment: Outlook and Recent Implications in Nanomedical Approaches Pharmacological Research. Aug, 2010 | Pubmed ID: 20117211 Proteomic and Biochemical Analyses Unveil Tight Interaction of Ataxin-3 with Tubulin The International Journal of Biochemistry & Cell Biology. Dec, 2009 | Pubmed ID: 19666135 Isolation of Primary Cancer-Associated Fibroblasts from a Syngeneic Murine Model of Breast Cancer for the Study of Targeted Nanoparticles Marta Truffi*1, Leopoldo Sitia*2, Marta Sevieri2, Arianna Bonizzi2, Maria Antonietta Rizzuto3, Serena Mazzucchelli2, Fabio Corsi1,2 1Istituti Clinici Scientifici Maugeri IRCCS, 2Dipartimento di Scienze Biomediche e Cliniche “L. Sacco”, Università di Milano, 3Dipartimento di Biotecnologie e Bioscienze, Università di Milano-Bicocca JoVE 62504 Pesquisa do câncer In Vitro Permeation of FITC-loaded Ferritins Across a Rat Blood-brain Barrier: a Model to Study the Delivery of Nanoformulated Molecules Luisa Fiandra1, Serena Mazzucchelli1, Marta Truffi1, Michela Bellini2, Luca Sorrentino1, Fabio Corsi1 1Dipartimento di Scienze Biomediche e Cliniche Luigi Sacco, Università di Milano, 2Dipartimento di Biotecnologie e Bioscienze, Università di Milano-Bicocca JoVE 54279 Bioengenharia
Isolation of Primary Cancer-Associated Fibroblasts from a Syngeneic Murine Model of Breast Cancer for the Study of Targeted Nanoparticles Marta Truffi*1, Leopoldo Sitia*2, Marta Sevieri2, Arianna Bonizzi2, Maria Antonietta Rizzuto3, Serena Mazzucchelli2, Fabio Corsi1,2 1Istituti Clinici Scientifici Maugeri IRCCS, 2Dipartimento di Scienze Biomediche e Cliniche “L. Sacco”, Università di Milano, 3Dipartimento di Biotecnologie e Bioscienze, Università di Milano-Bicocca JoVE 62504 Pesquisa do câncer
In Vitro Permeation of FITC-loaded Ferritins Across a Rat Blood-brain Barrier: a Model to Study the Delivery of Nanoformulated Molecules Luisa Fiandra1, Serena Mazzucchelli1, Marta Truffi1, Michela Bellini2, Luca Sorrentino1, Fabio Corsi1 1Dipartimento di Scienze Biomediche e Cliniche Luigi Sacco, Università di Milano, 2Dipartimento di Biotecnologie e Bioscienze, Università di Milano-Bicocca JoVE 54279 Bioengenharia