Sreejayan Nair School of Pharmacy University of Wyoming Biography Publications Institution JoVE Articles Sreejayan Nair has not added a biography. If you are Sreejayan Nair and would like to personalize this page please email our Author Liaison for assistance. Publications Antioxidant Metallothionein Alleviates Endoplasmic Reticulum Stress-Induced Myocardial Apoptosis and Contractile Dysfunction Free Radical Research. May, 2015 | Pubmed ID: 25968954 Cathepsin K Knockout Alleviates Aging-induced Cardiac Dysfunction Aging Cell. Jun, 2015 | Pubmed ID: 25692548 Deletion of Protein Tyrosine Phosphatase 1B Rescues Against Myocardial Anomalies in High Fat Diet-induced Obesity: Role of AMPK-dependent Autophagy Biochimica Et Biophysica Acta. Feb, 2015 | Pubmed ID: 25018087 Proteases in Cardiometabolic Diseases: Pathophysiology, Molecular Mechanisms and Clinical Applications Biochimica Et Biophysica Acta. Feb, 2015 | Pubmed ID: 24815358 Contribution of ALDH2 Polymorphism to Alcoholism-associated Hypertension Recent Patents on Endocrine, Metabolic & Immune Drug Discovery. 2014 | Pubmed ID: 25354396 AMP-activated Protein Kinase Deficiency Rescues Paraquat-induced Cardiac Contractile Dysfunction Through an Autophagy-dependent Mechanism Toxicological Sciences : an Official Journal of the Society of Toxicology. Nov, 2014 | Pubmed ID: 25092649 Neuronostatin Attenuates Myocardial Contractile Function Through Inhibition of Sarcoplasmic Reticulum Ca2+-ATPase in Murine Heart Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2014 | Pubmed ID: 25012062 Novel Curcumin Derivative CNB-001 Mitigates Obesity-associated Insulin Resistance The Journal of Pharmacology and Experimental Therapeutics. May, 2014 | Pubmed ID: 24549372 Macrophage Migration Inhibitory Factor Deletion Exacerbates Pressure Overload-induced Cardiac Hypertrophy Through Mitigating Autophagy Hypertension. Mar, 2014 | Pubmed ID: 24366076 Protein Tyrosine Phosphatase 1B and Insulin Resistance: Role of Endoplasmic Reticulum Stress/reactive Oxygen Species/nuclear Factor Kappa B Axis PloS One. 2013 | Pubmed ID: 24204775 Influence of Gestational Overfeeding on Myocardial Proinflammatory Mediators in Fetal Sheep Heart The Journal of Nutritional Biochemistry. Nov, 2013 | Pubmed ID: 24075902 Apelin Administration Ameliorates High Fat Diet-induced Cardiac Hypertrophy and Contractile Dysfunction Journal of Molecular and Cellular Cardiology. Jul, 2013 | Pubmed ID: 23859766 Bisdemethoxycurcumin Inhibits PDGF-induced Vascular Smooth Muscle Cell Motility and Proliferation Molecular Nutrition & Food Research. Sep, 2013 | Pubmed ID: 23554078 Cathepsin K Knockout Alleviates Pressure Overload-induced Cardiac Hypertrophy Hypertension. Jun, 2013 | Pubmed ID: 23529168 Chronic Akt Activation Attenuated Lipopolysaccharide-induced Cardiac Dysfunction Via Akt/GSK3β-dependent Inhibition of Apoptosis and ER Stress Biochimica Et Biophysica Acta. Jun, 2013 | Pubmed ID: 23474308 Cardiomyocyte-specific Deletion of Endothelin Receptor A Rescues Aging-associated Cardiac Hypertrophy and Contractile Dysfunction: Role of Autophagy Basic Research in Cardiology. Mar, 2013 | Pubmed ID: 23381122 Akt2 Knockout Preserves Cardiac Function in High-fat Diet-induced Obesity by Rescuing Cardiac Autophagosome Maturation Journal of Molecular Cell Biology. Feb, 2013 | Pubmed ID: 23258696 Cathepsin K Knockout Mitigates High-fat Diet-induced Cardiac Hypertrophy and Contractile Dysfunction Diabetes. Feb, 2013 | Pubmed ID: 23069627 Autophagy and Cardiovascular Aging: Lesson Learned from Rapamycin Cell Cycle (Georgetown, Tex.). Jun, 2012 | Pubmed ID: 22580468 Molecular Mechanisms of Chromium in Alleviating Insulin Resistance The Journal of Nutritional Biochemistry. Apr, 2012 | Pubmed ID: 22423897 Overcoming Cisplatin Resistance Using Gold(III) Mimics: Anticancer Activity of Novel Gold(III) Polypyridyl Complexes Journal of Inorganic Biochemistry. Jan, 2012 | Pubmed ID: 22112837 Chromium (D-phenylalanine)3 Alleviates High Fat-induced Insulin Resistance and Lipid Abnormalities Journal of Inorganic Biochemistry. Jan, 2011 | Pubmed ID: 21134603 Endoplasmic Reticulum Chaperon Tauroursodeoxycholic Acid Alleviates Obesity-induced Myocardial Contractile Dysfunction Journal of Molecular and Cellular Cardiology. Jan, 2011 | Pubmed ID: 21035453 Safety and Toxicological Evaluation of a Novel Chromium(III) Dinicocysteinate Complex Toxicology Mechanisms and Methods. Jul, 2010 | Pubmed ID: 20515439 AMP-activated Protein Kinase (AMPK) Cross-talks with Canonical Wnt Signaling Via Phosphorylation of Beta-catenin at Ser 552 Biochemical and Biophysical Research Communications. Apr, 2010 | Pubmed ID: 20361929 Tauroursodeoxycholic Acid Attenuates Lipid Accumulation in Endoplasmic Reticulum-stressed Macrophages Journal of Cardiovascular Pharmacology. Jan, 2010 | Pubmed ID: 19834331 2-(3,4-Dihydro-2H-pyrrolium-1-yl)-3oxoindan-1-olate (DHPO), a Novel, Synthetic Small Molecule That Alleviates Insulin Resistance and Lipid Abnormalities Biochemical Pharmacology. Feb, 2010 | Pubmed ID: 19769946 A Newly Synthetic Chromium Complex-chromium (D-phenylalanine)3 Activates AMP-activated Protein Kinase and Stimulates Glucose Transport Biochemical Pharmacology. Mar, 2009 | Pubmed ID: 19073152 Chromium Supplement Inhibits Skeletal Muscle Atrophy in Hindlimb-suspended Mice The Journal of Nutritional Biochemistry. Dec, 2009 | Pubmed ID: 19071005 Inhibitory Effect of Dehydrozingerone on Vascular Smooth Muscle Cell Function Journal of Cardiovascular Pharmacology. Nov, 2008 | Pubmed ID: 19033821 Chromium (D-phenylalanine)3 Supplementation Alters Glucose Disposal, Insulin Signaling, and Glucose Transporter-4 Membrane Translocation in Insulin-resistant Mice The Journal of Nutrition. Oct, 2008 | Pubmed ID: 18806091 Antioxidant Properties of Argpyrimidine European Journal of Pharmacology. Sep, 2008 | Pubmed ID: 18692042 Chromium Alleviates Glucose Intolerance, Insulin Resistance, and Hepatic ER Stress in Obese Mice Obesity (Silver Spring, Md.). Jun, 2008 | Pubmed ID: 18388893 IGF-I Alleviates Diabetes-induced RhoA Activation, ENOS Uncoupling, and Myocardial Dysfunction American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Mar, 2008 | Pubmed ID: 18199585 Isolation and Functional Studies of Rat Aortic Smooth Muscle Cells Methods in Molecular Medicine. 2007 | Pubmed ID: 18287680 Chromium (D-phenylalanine)3 Improves Obesity-induced Cardiac Contractile Defect in Ob/ob Mice Obesity (Silver Spring, Md.). Nov, 2007 | Pubmed ID: 18070761 Insulin-like Growth Factor I Deficiency Prolongs Survival and Antagonizes Paraquat-induced Cardiomyocyte Dysfunction: Role of Oxidative Stress Rejuvenation Research. Dec, 2007 | Pubmed ID: 17979500 Impact of Insulin-like Growth Factor-I on Migration, Proliferation and Akt-ERK Signaling in Early and Late-passages of Vascular Smooth Muscle Cells Cardiovascular Toxicology. 2007 | Pubmed ID: 17960499 Metallothionein Prevents High-fat Diet Induced Cardiac Contractile Dysfunction: Role of Peroxisome Proliferator Activated Receptor Gamma Coactivator 1alpha and Mitochondrial Biogenesis Diabetes. Sep, 2007 | Pubmed ID: 17575086 Acetaldehyde Promotes Rapamycin-dependent Activation of P70(S6K) and Glucose Uptake Despite Inhibition of Akt and MTOR in Dopaminergic SH-SY5Y Human Neuroblastoma Cells Experimental Neurology. Jan, 2007 | Pubmed ID: 16962100 Metallothionein Alleviates Cardiac Dysfunction in Streptozotocin-induced Diabetes: Role of Ca2+ Cycling Proteins, NADPH Oxidase, Poly(ADP-Ribose) Polymerase and Myosin Heavy Chain Isozyme Free Radical Biology & Medicine. Apr, 2006 | Pubmed ID: 16631532 Metallothionein Antagonizes Aging-induced Cardiac Contractile Dysfunction: Role of PTP1B, Insulin Receptor Tyrosine Phosphorylation and Akt Aging Cell. Apr, 2006 | Pubmed ID: 16626396 Metallothionein Prolongs Survival and Antagonizes Senescence-associated Cardiomyocyte Diastolic Dysfunction: Role of Oxidative Stress FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. May, 2006 | Pubmed ID: 16585059 Insulin-sensitizing and Cholesterol-lowering Effects of Chromium (D-Phenylalanine)3 Journal of Inorganic Biochemistry. Jul, 2006 | Pubmed ID: 16545457 Curcumin Inhibits Platelet-derived Growth Factor-stimulated Vascular Smooth Muscle Cell Function and Injury-induced Neointima Formation Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2006 | Pubmed ID: 16239599 Views from Within and Beyond: Narratives of Cardiac Contractile Dysfunction Under Senescence Endocrine. Mar, 2005 | Pubmed ID: 15888924 Aging Induces Cardiac Diastolic Dysfunction, Oxidative Stress, Accumulation of Advanced Glycation Endproducts and Protein Modification Aging Cell. Apr, 2005 | Pubmed ID: 15771609 A Newly Synthetic Chromium Complex--chromium(phenylalanine)3 Improves Insulin Responsiveness and Reduces Whole Body Glucose Tolerance FEBS Letters. Feb, 2005 | Pubmed ID: 15733857 Protein-tyrosine Phosphatase-1B (PTP1B) Mediates the Anti-migratory Actions of Sprouty The Journal of Biological Chemistry. Jan, 2003 | Pubmed ID: 12414790 Nitric Oxide-induced Motility in Aortic Smooth Muscle Cells: Role of Protein Tyrosine Phosphatase SHP-2 and GTP-binding Protein Rho Circulation Research. Sep, 2002 | Pubmed ID: 12215487 NO Attenuates Insulin Signaling and Motility in Aortic Smooth Muscle Cells Via Protein Tyrosine Phosphatase 1B-mediated Mechanism Arteriosclerosis, Thrombosis, and Vascular Biology. Jul, 2002 | Pubmed ID: 12117721 La eliminación de oligoelementos por cúprico Óxido nanopartículas de uranio Jodi R. Schilz1, K. J. Reddy2, Sreejayan Nair3, Thomas E. Johnson4, Ronald B. Tjalkens5, Kem P. Krueger3, Suzanne Clark6 1Division of Physical Therapy, Department of Orthopedics & Rehabilitation, University of New Mexico, 2Department of Ecosystem Science and Management, University of Wyoming, 3School of Pharmacy, University of Wyoming, 4Department of Environmental and Radiological Health Sciences, Colorado State University, 5Center for Environmental Medicine, Colorado State University, 6College of Pharmacy, California Northstate University Ciências Ambientais
La eliminación de oligoelementos por cúprico Óxido nanopartículas de uranio Jodi R. Schilz1, K. J. Reddy2, Sreejayan Nair3, Thomas E. Johnson4, Ronald B. Tjalkens5, Kem P. Krueger3, Suzanne Clark6 1Division of Physical Therapy, Department of Orthopedics & Rehabilitation, University of New Mexico, 2Department of Ecosystem Science and Management, University of Wyoming, 3School of Pharmacy, University of Wyoming, 4Department of Environmental and Radiological Health Sciences, Colorado State University, 5Center for Environmental Medicine, Colorado State University, 6College of Pharmacy, California Northstate University Ciências Ambientais