Stephen Rittenhouse Antibacterial Discovery Performance Unit GlaxoSmithKline Biography Publications Institution JoVE Articles Stephen Rittenhouse has not added a biography. If you are Stephen Rittenhouse and would like to personalize this page please email our Author Liaison for assistance. Publications In Vitro Antimicrobial Activity of S-649266, a Catechol-substituted Siderophore Cephalosporin, when Tested Against Non-fermenting Gram-negative Bacteria The Journal of Antimicrobial Chemotherapy. Mar, 2016 | Pubmed ID: 26645269 In Vitro Antimicrobial Activity of a Siderophore Cephalosporin, S-649266, Against Enterobacteriaceae Clinical Isolates, Including Carbapenem-Resistant Strains Antimicrobial Agents and Chemotherapy. Feb, 2016 | Pubmed ID: 26574013 Pharmacokinetics/Pharmacodynamics of Peptide Deformylase Inhibitor GSK1322322 Against Streptococcus Pneumoniae, Haemophilus Influenzae, and Staphylococcus Aureus in Rodent Models of Infection Antimicrobial Agents and Chemotherapy. Oct, 2015 | Pubmed ID: 26482300 Bacterial Resistance to Leucyl-tRNA Synthetase Inhibitor GSK2251052 Develops During Treatment of Complicated Urinary Tract Infections Antimicrobial Agents and Chemotherapy. Jan, 2015 | Pubmed ID: 25348524 新型氨基-piperidines 作为针对细菌类型 IIA Topoisomerases 强效抗菌药物。 Bioorganic & Medicinal Chemistry Letters. Dec, 2011 | Pubmed ID: 22047689 针对细菌类型 IIA Topoisomerases 强效抗菌药物作为新型环己酰胺。 Bioorganic & Medicinal Chemistry Letters. Dec, 2011 | Pubmed ID: 22030032 Challenges of Antibacterial Discovery Revisited Annals of the New York Academy of Sciences. Dec, 2010 | Pubmed ID: 21058956 A Rapid Microtiter Plate Assay for Measuring the Effect of Compounds on Staphylococcus Aureus Membrane Potential Journal of Microbiological Methods. Nov, 2010 | Pubmed ID: 20801170 Genetic Characterization of Vga ABC Proteins Conferring Reduced Susceptibility to Pleuromutilins in Staphylococcus Aureus Antimicrobial Agents and Chemotherapy. Dec, 2008 | Pubmed ID: 18838584 Stepwise Exposure of Staphylococcus Aureus to Pleuromutilins is Associated with Stepwise Acquisition of Mutations in RplC and Minimally Affects Susceptibility to Retapamulin Antimicrobial Agents and Chemotherapy. Jun, 2007 | Pubmed ID: 17404009 Use of the Surgical Wound Infection Model to Determine the Efficacious Dosing Regimen of Retapamulin, a Novel Topical Antibiotic Antimicrobial Agents and Chemotherapy. Nov, 2006 | Pubmed ID: 17065626 Selection of Retapamulin, a Novel Pleuromutilin for Topical Use Antimicrobial Agents and Chemotherapy. Nov, 2006 | Pubmed ID: 17065625 Definition of the Heterocyclic Pharmacophore of Bacterial Methionyl TRNA Synthetase Inhibitors: Potent Antibacterially Active Non-quinolone Analogues Bioorganic & Medicinal Chemistry Letters. Aug, 2004 | Pubmed ID: 15225702 New Benzylidenethiazolidinediones As Antibacterial Agents Bioorganic & Medicinal Chemistry Letters. Nov, 2003 | Pubmed ID: 14552776 Variable Sensitivity to Bacterial Methionyl-tRNA Synthetase Inhibitors Reveals Subpopulations of Streptococcus Pneumoniae with Two Distinct Methionyl-tRNA Synthetase Genes Antimicrobial Agents and Chemotherapy. Jun, 2003 | Pubmed ID: 12760849 Indole Naphthyridinones As Inhibitors of Bacterial Enoyl-ACP Reductases FabI and FabK Journal of Medicinal Chemistry. Apr, 2003 | Pubmed ID: 12699381 Conformational Restriction of Methionyl TRNA Synthetase Inhibitors Leading to Analogues with Potent Inhibition and Excellent Gram-positive Antibacterial Activity Bioorganic & Medicinal Chemistry Letters. Apr, 2003 | Pubmed ID: 12657260 Optimisation of Aryl Substitution Leading to Potent Methionyl TRNA Synthetase Inhibitors with Excellent Gram-positive Antibacterial Activity Bioorganic & Medicinal Chemistry Letters. Feb, 2003 | Pubmed ID: 12639554 Defining and Combating the Mechanisms of Triclosan Resistance in Clinical Isolates of Staphylococcus Aureus Antimicrobial Agents and Chemotherapy. Nov, 2002 | Pubmed ID: 12384334 Discovery of a Novel and Potent Class of FabI-directed Antibacterial Agents Antimicrobial Agents and Chemotherapy. Oct, 2002 | Pubmed ID: 12234833 Discovery of Aminopyridine-based Inhibitors of Bacterial Enoyl-ACP Reductase (FabI) Journal of Medicinal Chemistry. Jul, 2002 | Pubmed ID: 12109908 Identification of a Series of Tricyclic Natural Products As Potent Broad-spectrum Inhibitors of Metallo-beta-lactamases Antimicrobial Agents and Chemotherapy. Jun, 2002 | Pubmed ID: 12019104 Nanomolar Inhibitors of Staphylococcus Aureus Methionyl TRNA Synthetase with Potent Antibacterial Activity Against Gram-positive Pathogens Journal of Medicinal Chemistry. May, 2002 | Pubmed ID: 11985462 在免疫鼠害的鲁棒性肺炎模型评价抗菌功效反对 Jennifer L. Hoover1, Thomas F. Lewandowski1, Cindy L. Mininger1, Christine M. Singley1, Scott Sucoloski1, Stephen Rittenhouse1 1Antibacterial Discovery Performance Unit, GlaxoSmithKline Imunologia e Infecção
在免疫鼠害的鲁棒性肺炎模型评价抗菌功效反对 Jennifer L. Hoover1, Thomas F. Lewandowski1, Cindy L. Mininger1, Christine M. Singley1, Scott Sucoloski1, Stephen Rittenhouse1 1Antibacterial Discovery Performance Unit, GlaxoSmithKline Imunologia e Infecção