Sung-Su Kim Research Institute of Pharmaceutical Science, Department of Pharmacy, College of Pharmacy Seoul National University Biography Publications Institution JoVE Articles Sung-Su Kim has not added a biography. If you are Sung-Su Kim and would like to personalize this page please email our Author Liaison for assistance. Publications In Vitro Antifungal Activity and Mode of Action of 2',4'-Dihydroxychalcone Against Aspergillus Fumigatus Mycobiology. Jun, 2015 | Pubmed ID: 26190922 Phospholipase A2 Inhibits Cisplatin-induced Acute Kidney Injury by Modulating Regulatory T Cells by the CD206 Mannose Receptor Kidney International. Sep, 2015 | Pubmed ID: 25993317 Effect of Sulfonylureas Administered Centrally on the Blood Glucose Level in Immobilization Stress Model The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology. May, 2015 | Pubmed ID: 25954123 Korean Medicine Therapy As a Substitute for Chemotherapy for Metastatic Breast Cancer: a Case Report Case Reports in Oncology. Jan-Apr, 2015 | Pubmed ID: 25848354 Benefit of Implantable Cardioverter-defibrillator Therapy After Generator Replacement in Patients with Brugada Syndrome International Journal of Cardiology. May, 2015 | Pubmed ID: 25839639 A Case of Metastatic Bladder Cancer in Both Lungs Treated with Korean Medicine Therapy Alone Case Reports in Oncology. May, 2014 | Pubmed ID: 25232323 Effect of Pertussis and Cholera Toxins Administered Supraspinally on CA3 Hippocampal Neuronal Cell Death and the Blood Glucose Level Induced by Kainic Acid in Mice Neuroscience Research. Dec, 2014 | Pubmed ID: 25218563 Activation of Spinal α2 Adrenergic Receptors Induces Hyperglycemia in Mouse Though Activating Sympathetic Outflow European Journal of Pharmacology. Oct, 2014 | Pubmed ID: 25179570 Pertussis Toxin Administered Spinally Induces a Hypoglycemic Effect on Normal and Diabetic Mice Pharmacology. 2014 | Pubmed ID: 25171426 Metastatic Colorectal Cancer Treated with Herbal Pharmacopuncture During FOLFIRI Chemotherapy: A Case Report Case Reports in Oncology. May, 2014 | Pubmed ID: 24987356 Synergistic Effect of Ginsenoside Rg3 with Verapamil on the Modulation of Multidrug Resistance in Human Acute Myeloid Leukemia Cells Oncology Letters. Apr, 2014 | Pubmed ID: 24944704 The Modulatory Role of Alpha-melanocyte Stimulating Hormone Administered Spinally in the Regulation of Blood Glucose Level in D-glucose-fed and Restraint Stress Mouse Models Neuropeptides. Aug, 2014 | Pubmed ID: 24912936 Clinical Implications of T-wave Inversion in an Asymptomatic Population Undergoing Annual Medical Screening (from the Korean Air Forces Electrocardiogram Screening) The American Journal of Cardiology. May, 2014 | Pubmed ID: 24731653 Effect of Tolbutamide, Glyburide and Glipizide Administered Supraspinally on CA3 Hippocampal Neuronal Cell Death and Hyperglycemia Induced by Kainic Acid in Mice Brain Research. May, 2014 | Pubmed ID: 24713348 Effects of Nateglinide and Repaglinide Administered Intracerebroventricularly on the CA3 Hippocampal Neuronal Cell Death and Hyperglycemia Induced by Kainic Acid in Mice Brain Research Bulletin. May, 2014 | Pubmed ID: 24704461 The Modulatory Role of Spinally Located Histamine Receptors in the Regulation of the Blood Glucose Level in D-glucose-fed Mice The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology. Feb, 2014 | Pubmed ID: 24634595 Ghrelin Administered Spinally Increases the Blood Glucose Level in Mice Peptides. Apr, 2014 | Pubmed ID: 24472858 Repaglinide, but Not Nateglinide Administered Supraspinally and Spinally Exerts an Anti-diabetic Action in D-glucose Fed and Streptozotocin-treated Mouse Models The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology. Dec, 2013 | Pubmed ID: 24381497 A Case of Stage IV Non-Small Cell Lung Cancer Treated with Korean Medicine Therapy Alone Case Reports in Oncology. 2013 | Pubmed ID: 24348396 Targeting Biliverdin Reductase Overcomes Multidrug Resistance in Leukemia HL60 Cells Anticancer Research. Nov, 2013 | Pubmed ID: 24222129 Biliverdin Reductase Plays a Crucial Role in Hypoxia-induced Chemoresistance in Human Glioblastoma Biochemical and Biophysical Research Communications. Nov, 2013 | Pubmed ID: 24113378 Antinociceptive Profiles and Mechanisms of Orally Administered Coumarin in Mice Biological & Pharmaceutical Bulletin. 2013 | Pubmed ID: 23727914 The Developmental Regulators, FlbB and FlbE, Are Involved in the Virulence of Aspergillus Fumigatus Journal of Microbiology and Biotechnology. Jun, 2013 | Pubmed ID: 23676908 Effect of Cholera Toxin Administered Supraspinally or Spinally on the Blood Glucose Level in Pain and D-glucose Fed Animal Models The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology. Apr, 2013 | Pubmed ID: 23626479 Mechanisms Involved in the Antinociceptive Effects of Orally Administered Oleanolic Acid in the Mouse Archives of Pharmacal Research. Jul, 2013 | Pubmed ID: 23515934 Effect of GABA Receptor Agonists or Antagonists Injected Spinally on the Blood Glucose Level in Mice Neurochemical Research. Mar, 2013 | Pubmed ID: 23508311 Improvement of Andropause Symptoms by Dandelion and Rooibos Extract Complex CRS-10 in Aging Male Nutrition Research and Practice. Dec, 2012 | Pubmed ID: 23346300 Effect of the Mn Oxidation State and Lattice Oxygen in Mn-based TiO2 Catalysts on the Low-temperature Selective Catalytic Reduction of NO by NH3 Journal of the Air & Waste Management Association (1995). Sep, 2012 | Pubmed ID: 23019822 A Voxel-based Morphometric Study of Cortical Gray Matter Volume Changes in Alzheimer's Disease with White Matter Hyperintensities Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. Nov, 2012 | Pubmed ID: 22989793 Pore Control Using the Nano Structured Powders on the Fabrication of Porous Membrane and Its Application Journal of Nanoscience and Nanotechnology. Jul, 2012 | Pubmed ID: 22966611 Central Anti-diabetic Action of Biguanide and Thizolidinediones in D-glucose Fed and Streptozotocin-treated Mouse Models Neuroscience Letters. Oct, 2012 | Pubmed ID: 22960361 Chronic Treatment with Ginsenoside Rg3 Induces Akt-dependent Senescence in Human Glioma Cells International Journal of Oncology. Nov, 2012 | Pubmed ID: 22922739 Hop Extract Produces Antinociception by Acting on Opioid System in Mice The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology. Jun, 2012 | Pubmed ID: 22802700 In Situ Shaping of Pt Nanoparticles Directly Overgrown on Carbon Supports Chemical Communications (Cambridge, England). May, 2012 | Pubmed ID: 22614819 Improving the Activity of Mn/TiO2 Catalysts Through Control of the PH and Valence State of Mn During Their Preparation Journal of the Air & Waste Management Association (1995). Mar, 2012 | Pubmed ID: 22482293 Physicochemical Properties of Chars at Different Treatment Temperatures Journal of the Air & Waste Management Association (1995). Feb, 2012 | Pubmed ID: 22442939 Claudin-4 Overexpression is Associated with Epigenetic Derepression in Gastric Carcinoma Laboratory Investigation; a Journal of Technical Methods and Pathology. Nov, 2011 | Pubmed ID: 21844869 A Study on the Reaction Characteristics of Vanadium-impregnated Natural Manganese Oxide in Ammonia Selective Catalytic Reduction Journal of the Air & Waste Management Association (1995). May, 2011 | Pubmed ID: 21608495 Voxel-based Morphometric Study of Brain Volume Changes in Patients with Alzheimer's Disease Assessed According to the Clinical Dementia Rating Score Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. Jul, 2011 | Pubmed ID: 21570296 Characteristics of Fundamental Combustion and NOx Emission Using Various Rank Coals Journal of the Air & Waste Management Association (1995). Mar, 2011 | Pubmed ID: 21416751 Amine-modified Single-walled Carbon Nanotubes Protect Neurons from Injury in a Rat Stroke Model Nature Nanotechnology. Feb, 2011 | Pubmed ID: 21278749 Activation of PERK Signaling Attenuates Abeta-mediated ER Stress PloS One. 2010 | Pubmed ID: 20463975 CD4+ TH1 Cells Generated by Ii-PADRE DNA at Prime Phase Are Important to Induce Effectors and Memory CD8+ T Cells Journal of Immunotherapy (Hagerstown, Md. : 1997). Jun, 2010 | Pubmed ID: 20463596 Genital Group B Streptococcus Carrier Rate and Serotype Distribution in Korean Pregnant Women: Implications for Group B Streptococcal Disease in Korean Neonates Journal of Perinatal Medicine. Jul, 2010 | Pubmed ID: 20297897 Process Development for Mycelial Growth and Polysaccharide Production in Tricholoma Matsutake Liquid Culture Journal of Bioscience and Bioengineering. Apr, 2010 | Pubmed ID: 20226376 A Western Eurasian Male is Found in 2000-year-old Elite Xiongnu Cemetery in Northeast Mongolia American Journal of Physical Anthropology. Jul, 2010 | Pubmed ID: 20091844 Derepression of CLDN3 and CLDN4 During Ovarian Tumorigenesis is Associated with Loss of Repressive Histone Modifications Carcinogenesis. Jun, 2010 | Pubmed ID: 20053926 Antiobesity Effect of Baicalin Involves the Modulations of Proadipogenic and Antiadipogenic Regulators of the Adipogenesis Pathway Phytotherapy Research : PTR. Nov, 2009 | Pubmed ID: 19813240 Doxorubicin Enhances CD4(+) T-cell Immune Responses by Inducing Expression of CD40 Ligand and 4-1BB International Immunopharmacology. Dec, 2009 | Pubmed ID: 19778641 Brain Factor-7 Extracted from Bombyx Mori Enhances Cognition and Attention in Normal Children Journal of Medicinal Food. Jun, 2009 | Pubmed ID: 19627215 Immunohistochemical Localization of Insulin-like Growth Factor Binding Protein 2 in the Central Nervous System of SOD1(G93A) Transgenic Mice Journal of Molecular Histology. Apr, 2009 | Pubmed ID: 19468844 Potent Inhibition of Human Cytochrome P450 1B1 by Tetramethoxystilbene Toxicology Letters. Aug, 2009 | Pubmed ID: 19463925 Effects of a Chemical Chaperone on Genetic Mutations in Alpha-galactosidase A in Korean Patients with Fabry Disease Experimental & Molecular Medicine. Jan, 2009 | Pubmed ID: 19287194 Validated Method for Determination of Mazindol in Human Plasma by Liquid Chromatography/tandem Mass Spectrometry Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. Apr, 2009 | Pubmed ID: 19272843 Mutation in the DNA-binding Domain of the EWS-Oct-4 Oncogene Results in Dominant Negative Activity That Interferes with EWS-Oct-4-mediated Transactivation International Journal of Cancer. Journal International Du Cancer. May, 2009 | Pubmed ID: 19170206 3-Oxoolean-12-en-27-oic Acid Isolated from Aceriphyllum Rossii Induces Caspase-8-dependent Apoptosis in Human Promyelocytic Leukemia HL-60 Cells Biological & Pharmaceutical Bulletin. Jan, 2009 | Pubmed ID: 19122287 Effects of (-) Epigallocatechin-3-gallate on Na(+) Currents in Rat Dorsal Root Ganglion Neurons European Journal of Pharmacology. Feb, 2009 | Pubmed ID: 19111536 Tissue Factor and Its Natural Inhibitor in Pre-eclampsia and SGA The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. Dec, 2008 | Pubmed ID: 19065458 Alcohol Enhances Abeta42-induced Neuronal Cell Death Through Mitochondrial Dysfunction FEBS Letters. Dec, 2008 | Pubmed ID: 19026642 Emergence of Hormonal and Redox Regulation of Galectin-1 in Placental Mammals: Implication in Maternal-fetal Immune Tolerance Proceedings of the National Academy of Sciences of the United States of America. Oct, 2008 | Pubmed ID: 18824694 Immunohistochemical Study on the Distribution of Insulin-like Growth Factor-binding Protein 4 in the Central Nervous System of SOD1(G93A) Transgenic Mice As an in Vivo Model of Amyotrophic Lateral Sclerosis Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft. Dec, 2008 | Pubmed ID: 18823765 Chorioamnionitis and Increased Galectin-1 Expression in PPROM --an Anti-inflammatory Response in the Fetal Membranes? American Journal of Reproductive Immunology (New York, N.Y. : 1989). Oct, 2008 | Pubmed ID: 18691335 Immunohistochemical Study on the Distribution of Glycogen Synthase Kinase 3alpha in the Central Nervous System of SOD1(G93A) Transgenic Mice Neurological Research. Nov, 2008 | Pubmed ID: 18671898 Over-expression of the Thrombin Receptor (PAR-1) in the Placenta in Preeclampsia: a Mechanism for the Intersection of Coagulation and Inflammation The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. Jun, 2008 | Pubmed ID: 18570113 Kynurenic Acid Attenuates MPP(+)-induced Dopaminergic Neuronal Cell Death Via a Bax-mediated Mitochondrial Pathway European Journal of Cell Biology. Jun, 2008 | Pubmed ID: 18462830 Short-term Efficacy of Enzyme Replacement Therapy in Korean Patients with Fabry Disease Journal of Korean Medical Science. Apr, 2008 | Pubmed ID: 18437007 Coexpression of Myofibroblast and Macrophage Markers: Novel Evidence for an in Vivo Plasticity of Chorioamniotic Mesodermal Cells of the Human Placenta Laboratory Investigation; a Journal of Technical Methods and Pathology. Apr, 2008 | Pubmed ID: 18227805 A Liquid Chromatography/positive Ion Tandem Mass Spectrometry Method for the Determination of Cilazapril and Cilazaprilat in Human Plasma Talanta. Jan, 2007 | Pubmed ID: 19071268 Immunohistochemical Study on the Distribution of Canonical Transient Receptor Potential Channels in Rat Basal Ganglia Neuroscience Letters. Jul, 2007 | Pubmed ID: 17590510 An Optimized Analytical Method of Fluconazole in Human Plasma by High-performance Liquid Chromatography with Ultraviolet Detection and Its Application to a Bioequivalence Study Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. Jun, 2007 | Pubmed ID: 17275423 Identification of Novel Mutations in the Human Ornithine Transcarbamylase (OTC) Gene of Korean Patients with OTC Deficiency and Transient Expression of the Mutant Proteins in Vitro Human Mutation. Nov, 2006 | Pubmed ID: 17041896 A Rapid and Sensitive Liquid Chromatography/positive Ion Tandem Mass Spectrometry Method for the Determination of Cimetropium in Human Plasma by Liquid-liquid Extraction Journal of Mass Spectrometry : JMS. Jul, 2006 | Pubmed ID: 16810649 Immunohistochemical Study on the Distribution of TRPC Channels in the Rat Hippocampus Brain Research. Apr, 2006 | Pubmed ID: 16580647 ERK1/2 Activation Attenuates TRAIL-induced Apoptosis Through the Regulation of Mitochondria-dependent Pathway Toxicology in Vitro : an International Journal Published in Association with BIBRA. Sep, 2006 | Pubmed ID: 16563693 Molecular Characterization of Two Acetylcholinesterase Genes from the Oriental Tobacco Budworm, Helicoverpa Assulta (Guenée) Biochimica Et Biophysica Acta. Feb, 2006 | Pubmed ID: 16352398 Baicalein Attenuates 6-hydroxydopamine-induced Neurotoxicity in SH-SY5Y Cells European Journal of Cell Biology. Nov, 2005 | Pubmed ID: 16323286 The Activation of ERK1/2 Via a Tyrosine Kinase Pathway Attenuates Trail-induced Apoptosis in HeLa Cells Cancer Investigation. 2005 | Pubmed ID: 16305985 Immunohistochemical Study on the Distribution of Neuronal Nitric Oxide Synthase-immunoreactive Neurons in the Spinal Cord of Aged Rat Journal of Molecular Histology. Jun, 2005 | Pubmed ID: 16240168 Poly(C) Binding Protein Family is a Transcription Factor in Mu-opioid Receptor Gene Expression Molecular Pharmacology. Sep, 2005 | Pubmed ID: 15933215 Hydrogen Peroxide-induced Alterations of Tight Junction Proteins in Bovine Brain Microvascular Endothelial Cells Microvascular Research. Nov, 2004 | Pubmed ID: 15501242 Mitogen-activated Protein Kinase/extracellular Signal-regulated Kinase Attenuates 3-hydroxykynurenine-induced Neuronal Cell Death Journal of Neurochemistry. Feb, 2004 | Pubmed ID: 14720214 Clinical Characteristics and Molecular Analysis of PIT1, PROP1,LHX3, and HESX1 in Combined Pituitary Hormone Deficiency Patients with Abnormal Pituitary MR Imaging Hormone Research. 2003 | Pubmed ID: 14646405 Expression and Purification of Enzymatically Active Forms of the Human Lysyl Oxidase-like Protein 4 The Journal of Biological Chemistry. Dec, 2003 | Pubmed ID: 14551188 The Involvement of Oxidative Stress in Tumor Necrosis Factor (TNF)-related Apoptosis-inducing Ligand (TRAIL)-induced Apoptosis in HeLa Cells Cancer Letters. Aug, 2002 | Pubmed ID: 12175526 P53 Mediates Ceramide-induced Apoptosis in SKN-SH Cells Oncogene. Mar, 2002 | Pubmed ID: 11960374 The Involvement of Reactive Oxygen Species (ROS) and P38 Mitogen-activated Protein (MAP) Kinase in TRAIL/Apo2L-induced Apoptosis FEBS Letters. Feb, 2002 | Pubmed ID: 11852102 Employing Digital Droplet PCR to Detect BRAF V600E Mutations in Formalin-fixed Paraffin-embedded Reference Standard Cell Lines Nirmal Rajasekaran1, Myung Ryurl Oh3, Sung-Su Kim1, Si Eun Kim3, Young Deug Kim4, Hyun-Jeung Choi2, Bohyun Byun2, Young Kee Shin1,2 1Research Institute of Pharmaceutical Science, Department of Pharmacy, College of Pharmacy, Seoul National University, 2The Center for Anti-Cancer CDx, N-Bio, Seoul National University, 3ABION CRO, 4ABION Inc., R&D Center JoVE 53190 Biologia
Employing Digital Droplet PCR to Detect BRAF V600E Mutations in Formalin-fixed Paraffin-embedded Reference Standard Cell Lines Nirmal Rajasekaran1, Myung Ryurl Oh3, Sung-Su Kim1, Si Eun Kim3, Young Deug Kim4, Hyun-Jeung Choi2, Bohyun Byun2, Young Kee Shin1,2 1Research Institute of Pharmaceutical Science, Department of Pharmacy, College of Pharmacy, Seoul National University, 2The Center for Anti-Cancer CDx, N-Bio, Seoul National University, 3ABION CRO, 4ABION Inc., R&D Center JoVE 53190 Biologia