Susan Clark Epigenetics Group, Cancer Research Program Garvan Institute of Medical Research Biography Publications Institution JoVE Articles Susan Clark has not added a biography. If you are Susan Clark and would like to personalize this page please email our Author Liaison for assistance. Publications A Basal Gradient of Wnt and Stem-cell Number Influences Regional Tumour Distribution in Human and Mouse Intestinal Tracts Gut. Jan, 2012 | Pubmed ID: 22287596 Prognostic and Diagnostic Significance of DNA Methylation Patterns in High Grade Serous Ovarian Cancer Gynecologic Oncology. Mar, 2012 | Pubmed ID: 22115852 Acetylation of H2A.Z is a Key Epigenetic Modification Associated with Gene Deregulation and Epigenetic Remodeling in Cancer Genome Research. Feb, 2012 | Pubmed ID: 21788347 Integrative Genome-wide Expression and Promoter DNA Methylation Profiling Identifies a Potential Novel Panel of Ovarian Cancer Epigenetic Biomarkers Cancer Letters. Dec, 2011 | Pubmed ID: 22155104 MicroRNA Alterations and Associated Aberrant DNA Methylation Patterns Across Multiple Sample Types in Oral Squamous Cell Carcinoma PloS One. 2011 | Pubmed ID: 22132151 The Development of a Social Morbidity Score in Patients with Chronic Ulcerative Colitis As a Potential Guide to Treatment Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland. Nov, 2011 | Pubmed ID: 22053990 Impact of the Genome on the Epigenome is Manifested in DNA Methylation Patterns of Imprinted Regions in Monozygotic and Dizygotic Twins PloS One. 2011 | Pubmed ID: 21991322 Human Gut-specific Homeostatic Dendritic Cells Are Generated from Blood Precursors by the Gut Microenvironment Inflammatory Bowel Diseases. Oct, 2011 | Pubmed ID: 21987473 MiRNA-dependent Gene Silencing Involving Ago2-mediated Cleavage of a Circular Antisense RNA The EMBO Journal. Nov, 2011 | Pubmed ID: 21964070 Key Challenges in Simulated Patient Programs: an International Comparative Case Study BMC Medical Education. 2011 | Pubmed ID: 21943295 Nurse Practitioner Management of Chronic Musculoskeletal Pain: a Chart Review The Nurse Practitioner. Sep, 2011 | Pubmed ID: 21857215 Dynamics of Bivalent Chromatin Domains Upon Drug Induced Reactivation and Resilencing in Cancer Cells Epigenetics : Official Journal of the DNA Methylation Society. Sep, 2011 | Pubmed ID: 21852760 Lineage Specific Methylation of the Elf5 Promoter in Mammary Epithelial Cells Stem Cells (Dayton, Ohio). Oct, 2011 | Pubmed ID: 21823211 Epigenetics in Prostate Cancer: Biologic and Clinical Relevance European Urology. Oct, 2011 | Pubmed ID: 21719191 Optimization and Validation of a Multiclass Screening and Confirmation Method for Drug Residues in Milk Using High-performance Liquid Chromatography/tandem Mass Spectrometry Journal of AOAC International. Mar-Apr, 2011 | Pubmed ID: 21563671 College and University Environmental Programs As a Policy Problem (part 1): Integrating Knowledge, Education, and Action for a Better World? Environmental Management. May, 2011 | Pubmed ID: 21359525 College and University Environmental Programs As a Policy Problem (part 2): Strategies for Improvement Environmental Management. May, 2011 | Pubmed ID: 21359524 CD154-CD40 Interactions in the Control of Murine B Cell Hematopoiesis Journal of Leukocyte Biology. May, 2011 | Pubmed ID: 21330346 Analysis of Veterinary Drugs and Metabolites in Milk Using Quadrupole Time-of-flight Liquid Chromatography-mass Spectrometry Journal of Agricultural and Food Chemistry. Jul, 2011 | Pubmed ID: 21284383 Discovery Pipeline for Epigenetically Deregulated MiRNAs in Cancer: Integration of Primary MiRNA Transcription BMC Genomics. 2011 | Pubmed ID: 21255435 Mucosectomy with Handsewn Anastomosis Reduces the Risk of Adenoma Formation in the Anorectal Segment After Restorative Proctocolectomy for Familial Adenomatous Polyposis Annals of Surgery. Feb, 2011 | Pubmed ID: 21173697 Epigenetic Deregulation Across Chromosome 2q14.2 Differentiates Normal from Prostate Cancer and Provides a Regional Panel of Novel DNA Methylation Cancer Biomarkers Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Jan, 2011 | Pubmed ID: 21098650 Colorectal Cancer: No Longer the Issue in Familial Adenomatous Polyposis? Familial Cancer. Mar, 2011 | Pubmed ID: 21052851 Comparison of Methyl-DNA Immunoprecipitation (MeDIP) and Methyl-CpG Binding Domain (MBD) Protein Capture for Genome-wide DNA Methylation Analysis Reveal CpG Sequence Coverage Bias Epigenetics : Official Journal of the DNA Methylation Society. Jan, 2011 | Pubmed ID: 20818161 Coordinated Epigenetic Repression of the MiR-200 Family and MiR-205 in Invasive Bladder Cancer International Journal of Cancer. Journal International Du Cancer. Mar, 2011 | Pubmed ID: 20473948 Epigenetic Architecture and MiRNA: Reciprocal Regulators Epigenomics. Dec, 2010 | Pubmed ID: 22122085 Protocol Matters: Which Methylome Are You Actually Studying? Epigenomics. Aug, 2010 | Pubmed ID: 21566704 Evaluation of Affinity-based Genome-wide DNA Methylation Data: Effects of CpG Density, Amplification Bias, and Copy Number Variation Genome Research. Dec, 2010 | Pubmed ID: 21045081 Severe Polyposis in Apc(1322T) Mice is Associated with Submaximal Wnt Signalling and Increased Expression of the Stem Cell Marker Lgr5 Gut. Dec, 2010 | Pubmed ID: 20926645 Prognostic Significance of Myocardial Fibrosis in Hypertrophic Cardiomyopathy Journal of the American College of Cardiology. Sep, 2010 | Pubmed ID: 20688032 Defining Responsibilities of Simulated Patients in Medical Education Simulation in Healthcare : Journal of the Society for Simulation in Healthcare. Jun, 2010 | Pubmed ID: 20651478 A Prospective Study of MR Enterography Versus Capsule Endoscopy for the Surveillance of Adult Patients with Peutz-Jeghers Syndrome AJR. American Journal of Roentgenology. Jul, 2010 | Pubmed ID: 20566803 The Bacteriology of Pouchitis: a Molecular Phylogenetic Analysis Using 16S RRNA Gene Cloning and Sequencing Annals of Surgery. Jul, 2010 | Pubmed ID: 20562611 Repitools: an R Package for the Analysis of Enrichment-based Epigenomic Data Bioinformatics (Oxford, England). Jul, 2010 | Pubmed ID: 20457667 Familial Adenomatous Polyposis (FAP) and Gender. Does Gender Influence the Genetic Transmission of FAP? Familial Cancer. Sep, 2010 | Pubmed ID: 20411341 Eicosapentaenoic Acid Reduces Rectal Polyp Number and Size in Familial Adenomatous Polyposis Gut. Jul, 2010 | Pubmed ID: 20348368 A Review of Weight Loss Following Roux-en-Y Gastric Bypass Vs Restrictive Bariatric Surgery: Impact on Adiponectin and Insulin Obesity Surgery. May, 2010 | Pubmed ID: 20177811 Consolidation of the Cancer Genome into Domains of Repressive Chromatin by Long-range Epigenetic Silencing (LRES) Reduces Transcriptional Plasticity Nature Cell Biology. Mar, 2010 | Pubmed ID: 20173741 The Role of Pouch Compliance Measurement in the Management of Pouch Dysfunction International Journal of Colorectal Disease. Apr, 2010 | Pubmed ID: 19924421 Osteoporosis in Patients over 50 Years of Age Following Restorative Proctocolectomy for Ulcerative Colitis: is DXA Screening Warranted? Inflammatory Bowel Diseases. Feb, 2010 | Pubmed ID: 19591132 Ultrafast Optical Spin Echo for Electron Spins in Semiconductors Physical Review Letters. Jun, 2009 | Pubmed ID: 19659047 A Mitotic Recombination Map Proximal to the APC Locus on Chromosome 5q and Assessment of Influences on Colorectal Cancer Risk BMC Medical Genetics. 2009 | Pubmed ID: 19515250 Incidence and Short-term Implications of Prepouch Ileitis Following Restorative Proctocolectomy with Ileal Pouch-anal Anastomosis for Ulcerative Colitis Diseases of the Colon and Rectum. May, 2009 | Pubmed ID: 19502851 Symptomatic Polyposis in a 4-year-old: the Exception Proves the Rule Journal of Paediatrics and Child Health. May, 2009 | Pubmed ID: 19493128 Aberrant De Novo Methylation of the P16INK4A CpG Island is Initiated Post Gene Silencing in Association with Chromatin Remodelling and Mimics Nucleosome Positioning Human Molecular Genetics. Aug, 2009 | Pubmed ID: 19477956 Fecal Coliform Testing to Identify Effective Antibiotic Therapies for Patients with Antibiotic-resistant Pouchitis Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. May, 2009 | Pubmed ID: 19418603 Multiresidue Method for the Triphenylmethane Dyes in Fish: Malachite Green, Crystal (gentian) Violet, and Brilliant Green Analytica Chimica Acta. Apr, 2009 | Pubmed ID: 19286041 Features of Duodenal Cancer in Patients with Familial Adenomatous Polyposis Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. Jun, 2009 | Pubmed ID: 19281862 Iron Deficiency Anemia: Diagnosis and Management Current Opinion in Gastroenterology. Mar, 2009 | Pubmed ID: 19262200 Guide to Endoscopy of the Ileo-anal Pouch Following Restorative Proctocolectomy with Ileal Pouch-anal Anastomosis; Indications, Technique, and Management of Common Findings Inflammatory Bowel Diseases. Aug, 2009 | Pubmed ID: 19180580 Low O6-methylguanine-DNA Methyltransferase (MGMT) Expression and Response to Temozolomide in Aggressive Pituitary Tumours Clinical Endocrinology. Aug, 2009 | Pubmed ID: 19067722 The Comparative Incidence of Reported Concussions Presenting for Follow-up Management in South African Rugby Union Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine. Sep, 2008 | Pubmed ID: 18806547 Epigenetic and Phenotypic Changes Result from a Continuous Pre and Post Natal Dietary Exposure to Phytoestrogens in an Experimental Population of Mice BMC Physiology. 2008 | Pubmed ID: 18793434 Putative Direct and Indirect Wnt Targets Identified Through Consistent Gene Expression Changes in APC-mutant Intestinal Adenomas from Humans and Mice Human Molecular Genetics. Dec, 2008 | Pubmed ID: 18782851 Climate Warming, Marine Protected Areas and the Ocean-scale Integrity of Coral Reef Ecosystems PloS One. 2008 | Pubmed ID: 18728776 Breast Cancer Epigenetics: Normal Human Mammary Epithelial Cells As a Model System Journal of Molecular Medicine (Berlin, Germany). Dec, 2008 | Pubmed ID: 18716754 The Risk of Oral Contraceptives in the Etiology of Inflammatory Bowel Disease: a Meta-analysis The American Journal of Gastroenterology. Sep, 2008 | Pubmed ID: 18684177 Persistent Perineal Sinus After Ileoanal Pouch Excision in Inflammatory Bowel Diseases: Incidence, Risk Factors, and Clinical Course Diseases of the Colon and Rectum. Dec, 2008 | Pubmed ID: 18626712 Epigenetic Markers of Ovarian Cancer Advances in Experimental Medicine and Biology. 2008 | Pubmed ID: 18546617 Determination and Confirmation of Melamine Residues in Catfish, Trout, Tilapia, Salmon, and Shrimp by Liquid Chromatography with Tandem Mass Spectrometry Journal of Agricultural and Food Chemistry. Jun, 2008 | Pubmed ID: 18494486 This is Your Future: a Case Study Approach to Foster Health Literacy The Journal of School Health. Jun, 2008 | Pubmed ID: 18489469 Iron Deficiency Anemia Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition. Apr-May, 2008 | Pubmed ID: 18390780 DNA Methylation Changes in Ovarian Cancer: Implications for Early Diagnosis, Prognosis and Treatment Gynecologic Oncology. Apr, 2008 | Pubmed ID: 18234305 Perception of Voice in the Transgender Client Journal of Voice : Official Journal of the Voice Foundation. Nov, 2008 | Pubmed ID: 17400427 Concordant Epigenetic Silencing of Transforming Growth Factor-beta Signaling Pathway Genes Occurs Early in Breast Carcinogenesis Cancer Research. Dec, 2007 | Pubmed ID: 18089780 Enhancing Health Literacy Through Accessing Health Information, Products, and Services: an Exercise for Children and Adolescents The Journal of School Health. Nov, 2007 | Pubmed ID: 17970869 Epigenetic Inactivation of a Cluster of Genes Flanking MLH1 in Microsatellite-unstable Colorectal Cancer Cancer Research. Oct, 2007 | Pubmed ID: 17909015 Genomic Profiling of CpG Methylation and Allelic Specificity Using Quantitative High-throughput Mass Spectrometry: Critical Evaluation and Improvements Nucleic Acids Research. 2007 | Pubmed ID: 17855397 Quantum Computers Based on Electron Spins Controlled by Ultrafast Off-resonant Single Optical Pulses Physical Review Letters. Jul, 2007 | Pubmed ID: 17678343 Action at a Distance: Epigenetic Silencing of Large Chromosomal Regions in Carcinogenesis Human Molecular Genetics. Apr, 2007 | Pubmed ID: 17613553 The Effect of Restorative Proctocolectomy on Sexual Function, Urinary Function, Fertility, Pregnancy and Delivery: a Systematic Review Diseases of the Colon and Rectum. Aug, 2007 | Pubmed ID: 17588223 The Impact of Technical Factors on Outcome of Restorative Proctocolectomy for Familial Adenomatous Polyposis Diseases of the Colon and Rectum. Jul, 2007 | Pubmed ID: 17464542 Homozygous PMS2 Deletion Causes a Severe Colorectal Cancer and Multiple Adenoma Phenotype Without Extraintestinal Cancer Gastroenterology. Feb, 2007 | Pubmed ID: 17258725 Bisulphite Differential Denaturation PCR for Analysis of DNA Methylation Epigenetics : Official Journal of the DNA Methylation Society. Apr-Jun, 2006 | Pubmed ID: 17998815 DNA Methylation: Bisulphite Modification and Analysis Nature Protocols. 2006 | Pubmed ID: 17406479 Exercise in the Heat: Effect of Fluid Ingestion on Blood-brain Barrier Permeability Medicine and Science in Sports and Exercise. Dec, 2006 | Pubmed ID: 17146318 Telomere-driven Karyotypic Complexity Concurs with P16INK4a Inactivation in TP53-competent Immortal Endothelial Cells Cancer Research. Nov, 2006 | Pubmed ID: 17108106 The Effect of Link Nurses on Hospital Readmission Rates Nursing Times. Oct 17-23, 2006 | Pubmed ID: 17066881 Current Ideas in Desmoid Tumours Familial Cancer. 2006 | Pubmed ID: 16998673 Epigenetic Remodeling in Colorectal Cancer Results in Coordinate Gene Suppression Across an Entire Chromosome Band Nature Genetics. May, 2006 | Pubmed ID: 16642018 Permissive Transcriptional Activity at the Centromere Through Pockets of DNA Hypomethylation PLoS Genetics. Feb, 2006 | Pubmed ID: 16477312 Headloop Suppression PCR and Its Application to Selective Amplification of Methylated DNA Sequences Nucleic Acids Research. 2005 | Pubmed ID: 16091627 Hypermethylation of the Prostacyclin Synthase (PTGIS) Promoter is a Frequent Event in Colorectal Cancer and Associated with Aneuploidy Oncogene. Nov, 2005 | Pubmed ID: 16007128 Confirmation of Sulfamethazine, Sulfathiazole, and Sulfadimethoxine Residues in Condensed Milk and Soft-cheese Products by Liquid Chromatography/tandem Mass Spectrometry Journal of AOAC International. May-Jun, 2005 | Pubmed ID: 16001847 Developing Empathy for Hearing-impaired Students: Can You Hear What I Hear? The Journal of School Health. Feb, 2005 | Pubmed ID: 15929597 All-optical Switching in Rubidium Vapor Science (New York, N.Y.). Apr, 2005 | Pubmed ID: 15860622 Evaluation of Decontamination Procedures Used in Primary Care Nursing Times. Sep 7-13, 2004 | Pubmed ID: 15478836 Incidence of Low Free T4 Values in Premature Infants As Determined by Direct Equilibrium Dialysis Journal of Perinatology : Official Journal of the California Perinatal Association. Oct, 2004 | Pubmed ID: 15306825 High-dose Tamoxifen and Sulindac As First-line Treatment for Desmoid Tumors Cancer. Aug, 2004 | Pubmed ID: 15274082 Alimentary Tract Surgery in the Nonagenarian: Elective Vs. Emergent Operations Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract. Jul-Aug, 2004 | Pubmed ID: 15239987 Transcriptional Gene Silencing Promotes DNA Hypermethylation Through a Sequential Change in Chromatin Modifications in Cancer Cells Cancer Research. Jun, 2004 | Pubmed ID: 15172996 Spirituality and Sexuality: Compatible Components for Optimal Health The Journal of School Health. Jan, 2004 | Pubmed ID: 15022373 Alterations in the P16(INK4a) and P53 Tumor Suppressor Genes of HTERT-immortalized Human Fibroblasts Oncogene. Apr, 2004 | Pubmed ID: 14743210 Health Professionals Helping the Community The Journal of School Health. Sep, 2003 | Pubmed ID: 14513632 Bisulfite Methylation Analysis of Tumor Suppressor Genes in Prostate Cancer from Fresh and Archival Tissue Samples Methods in Molecular Medicine. 2003 | Pubmed ID: 12725123 Stepwise Progression of Familial Adenomatous Polyposis-associated Desmoid Precursor Lesions Demonstrated by a Novel CT Scoring System Diseases of the Colon and Rectum. Apr, 2003 | Pubmed ID: 12682541 The Biochemistry of Antioxidants Revisited Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition. Feb, 2002 | Pubmed ID: 16214960 Interlaboratory Comparison of Methods for the Determination of Incurred Tilmicosin Residues in Bovine Liver Journal of AOAC International. Nov-Dec, 2002 | Pubmed ID: 12477187 A Question-and-answer Approach to Drug Education The Journal of School Health. Oct, 2002 | Pubmed ID: 12389376 Confirmation of Phenylbutazone Residues in Bovine Kidney by Liquid Chromatography/mass Spectrometry Journal of AOAC International. Sep-Oct, 2002 | Pubmed ID: 12374396 DNA Methylation Changes in Leukaemia Seminars in Cancer Biology. Oct, 2002 | Pubmed ID: 12191634 DNA Methylation and Gene Silencing in Cancer: Which is the Guilty Party? Oncogene. Aug, 2002 | Pubmed ID: 12154400 Conversion-specific Detection of DNA Methylation Using Real-time Polymerase Chain Reaction (ConLight-MSP) to Avoid False Positives Methods (San Diego, Calif.). Jun, 2002 | Pubmed ID: 12095268 Methylation Sequencing from Limiting DNA: Embryonic, Fixed, and Microdissected Cells Methods (San Diego, Calif.). Jun, 2002 | Pubmed ID: 12095267 Identification and Resolution of Artifacts in Bisulfite Sequencing Methods (San Diego, Calif.). Jun, 2002 | Pubmed ID: 12095266 DNA Methylation Analysis in Mammalian Cells Methods (San Diego, Calif.). Jun, 2002 | Pubmed ID: 12095265 "Tinkering" with the Components of Health The Journal of School Health. Jan, 2002 | Pubmed ID: 11865799 Hypermethylation Trigger of the Glutathione-S-transferase Gene (GSTP1) in Prostate Cancer Cells Oncogene. Feb, 2002 | Pubmed ID: 11850822 Hypermethylation of the Inhibin Alpha-subunit Gene in Prostate Carcinoma Molecular Endocrinology (Baltimore, Md.). Feb, 2002 | Pubmed ID: 11818495 DNA-methylatie: bisulfiet Wijziging en Analyse Kate Patterson*1, Laura Molloy*1, Wenjia Qu1, Susan Clark1,2 1Epigenetics Group, Cancer Research Program, Garvan Institute of Medical Research, 2St Vincent's Clinical School, University of NSW JoVE 3170 Biologia
DNA-methylatie: bisulfiet Wijziging en Analyse Kate Patterson*1, Laura Molloy*1, Wenjia Qu1, Susan Clark1,2 1Epigenetics Group, Cancer Research Program, Garvan Institute of Medical Research, 2St Vincent's Clinical School, University of NSW JoVE 3170 Biologia