Tian-Li Wang Department of Pathology Johns Hopkins University School of Medicine Biography Publications Institution JoVE Articles Tian-Li Wang has not added a biography. If you are Tian-Li Wang and would like to personalize this page please email our Author Liaison for assistance. Publications Ultrasensitive Detection of Circulating LINE-1 ORF1p As a Specific Multi-cancer Biomarker BioRxiv : the Preprint Server for Biology. Jan, 2023 | Pubmed ID: 36747644 Spatial Transcriptomic Analysis of Ovarian Cancer Precursors Reveals Reactivation of IGFBP2 During Pathogenesis Cancer Research. Dec, 2022 | Pubmed ID: 36206311 Targeting Glutamine Metabolism Enhances Responses to Platinum-based Chemotherapy in Triple-negative Breast Cancers (TNBC) Genes & Diseases. Nov, 2022 | Pubmed ID: 36157486 Treating ARID1A Mutated Cancers by Harnessing Synthetic Lethality and DNA Damage Response Journal of Biomedical Science. Sep, 2022 | Pubmed ID: 36123603 Current and Emerging Methods for Ovarian Cancer Screening and Diagnostics: A Comprehensive Review Cancers. Jun, 2022 | Pubmed ID: 35740550 Systems Medicine Dissection of Chr1q-amp Reveals a Novel PBX1-FOXM1 Axis for Targeted Therapy in Multiple Myeloma Blood. Mar, 2022 | Pubmed ID: 35015835 A Novel Human Endometrial Epithelial Cell Line for Modeling Gynecological Diseases and for Drug Screening Laboratory Investigation; a Journal of Technical Methods and Pathology. Nov, 2021 | Pubmed ID: 36775477 Development of Small Molecule Inhibitors Targeting PBX1 Transcription Signaling As a Novel Cancer Therapeutic Strategy IScience. Nov, 2021 | Pubmed ID: 34816098 Mutation and Methylation Profiles of Ectopic and Eutopic Endometrial Tissues The Journal of Pathology. Dec, 2021 | Pubmed ID: 34396532 A Novel Human Endometrial Epithelial Cell Line for Modeling Gynecological Diseases and for Drug Screening Laboratory Investigation; a Journal of Technical Methods and Pathology. Nov, 2021 | Pubmed ID: 34376780 Correction: -mutated Ovarian Serous Borderline Tumors Are at Relatively Low Risk for Progression to Serous Carcinoma Oncotarget. Jun, 2021 | Pubmed ID: 34194631 The Origin of Ovarian Cancer Species and Precancerous Landscape The American Journal of Pathology. Jan, 2021 | Pubmed ID: 33011111 Inhibition of the MYC-Regulated Glutaminase Metabolic Axis Is an Effective Synthetic Lethal Approach for Treating Chemoresistant Ovarian Cancers Cancer Research. Oct, 2020 | Pubmed ID: 32859605 Methylomic Landscapes of Ovarian Cancer Precursor Lesions Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2020 | Pubmed ID: 32817081 Inactivation of Arid1a in the Endometrium is Associated with Endometrioid Tumorigenesis Through Transcriptional Reprogramming Nature Communications. Jun, 2020 | Pubmed ID: 32483112 Assessing Aneuploidy with Repetitive Element Sequencing Proceedings of the National Academy of Sciences of the United States of America. Mar, 2020 | Pubmed ID: 32075918 Epithelial Cells in Endometriosis and Adenomyosis Upregulate STING Expression Reproductive Sciences (Thousand Oaks, Calif.). Jun, 2020 | Pubmed ID: 32046461 Molecular Classification and Emerging Targeted Therapy in Endometrial Cancer International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists. Jan, 2020 | Pubmed ID: 30741844 -mutated Ovarian Serous Borderline Tumors Are at Relatively Low Risk for Progression to Serous Carcinoma Oncotarget. Dec, 2019 | Pubmed ID: 31839880 Spleen Tyrosine Kinase Activity Regulates Epidermal Growth Factor Receptor Signaling Pathway in Ovarian Cancer EBioMedicine. Sep, 2019 | Pubmed ID: 31492560 Clinicopathologic and Molecular Features of Paired Cases of Metachronous Ovarian Serous Borderline Tumor and Subsequent Serous Carcinoma The American Journal of Surgical Pathology. Nov, 2019 | Pubmed ID: 31343420 Loss of ARID1A in Tumor Cells Renders Selective Vulnerability to Combined Ionizing Radiation and PARP Inhibitor Therapy Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2019 | Pubmed ID: 31196855 Uncovering the Role of N-Acetyl-Aspartyl-Glutamate As a Glutamate Reservoir in Cancer Cell Reports. Apr, 2019 | Pubmed ID: 30970252 Cytomorphologic and Molecular Analyses of Fallopian Tube Fimbrial Brushings for Diagnosis of Serous Tubal Intraepithelial Carcinoma Cancer Cytopathology. Mar, 2019 | Pubmed ID: 30861338 Genomic Characterization of Genes Encoding Histone Acetylation Modulator Proteins Identifies Therapeutic Targets for Cancer Treatment Nature Communications. Feb, 2019 | Pubmed ID: 30760718 PVRIG and PVRL2 Are Induced in Cancer and Inhibit CD8 T-cell Function Cancer Immunology Research. Feb, 2019 | Pubmed ID: 30659054 Fallopian Tube Lesions in Women at High Risk for Ovarian Cancer: A Multicenter Study Cancer Prevention Research (Philadelphia, Pa.). Nov, 2018 | Pubmed ID: 30232083 Methylomic Analysis of Ovarian Cancers Identifies Tumor-Specific Alterations Readily Detectable in Early Precursor Lesions Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2018 | Pubmed ID: 30108103 Inhibition of Ovarian Tumor Cell Invasiveness by Targeting SYK in the Tyrosine Kinase Signaling Pathway Oncogene. Jul, 2018 | Pubmed ID: 29643476 Evaluation of Liquid from the Papanicolaou Test and Other Liquid Biopsies for the Detection of Endometrial and Ovarian Cancers Science Translational Medicine. Mar, 2018 | Pubmed ID: 29563323 Detection and Localization of Surgically Resectable Cancers with a Multi-analyte Blood Test Science (New York, N.Y.). Feb, 2018 | Pubmed ID: 29348365 High Grade Serous Ovarian Carcinomas Originate in the Fallopian Tube Nature Communications. Oct, 2017 | Pubmed ID: 29061967 Mutation of NRAS is a Rare Genetic Event in Ovarian Low-grade Serous Carcinoma Human Pathology. Oct, 2017 | Pubmed ID: 28873354 Human Transposon Insertion Profiling: Analysis, Visualization and Identification of Somatic LINE-1 Insertions in Ovarian Cancer Proceedings of the National Academy of Sciences of the United States of America. Jan, 2017 | Pubmed ID: 28096347 PD-L1 Expression in Human Placentas and Gestational Trophoblastic Diseases International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists. Mar, 2017 | Pubmed ID: 27362903 Ovarian Cancer Chemoresistance Relies on the Stem Cell Reprogramming Factor PBX1 Cancer Research. Nov, 2016 | Pubmed ID: 27590741 Yes-associated Protein Impacts Adherens Junction Assembly Through Regulating Actin Cytoskeleton Organization American Journal of Physiology. Gastrointestinal and Liver Physiology. Sep, 2016 | Pubmed ID: 27229120 Inactivating ARID1A Tumor Suppressor Enhances TERT Transcription and Maintains Telomere Length in Cancer Cells The Journal of Biological Chemistry. Apr, 2016 | Pubmed ID: 26953344 Mevalonate Pathway Antagonist Suppresses Formation of Serous Tubal Intraepithelial Carcinoma and Ovarian Carcinoma in Mouse Models Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2015 | Pubmed ID: 26109099 Inhibition of Spleen Tyrosine Kinase Potentiates Paclitaxel-Induced Cytotoxicity in Ovarian Cancer Cells by Stabilizing Microtubules Cancer Cell. Jul, 2015 | Pubmed ID: 26096845 Notch3 Interactome Analysis Identified WWP2 As a Negative Regulator of Notch3 Signaling in Ovarian Cancer PLoS Genetics. Oct, 2014 | Pubmed ID: 25356737 Roles of Deletion of Arid1a, a Tumor Suppressor, in Mouse Ovarian Tumorigenesis Journal of the National Cancer Institute. Jul, 2014 | Pubmed ID: 24899687 The Emerging Roles of ARID1A in Tumor Suppression Cancer Biology & Therapy. Jun, 2014 | Pubmed ID: 24618703 Establishing Isogenic Inducible Cell Lines Using Founder Reporter Lines and Recombinase-mediated Cassette Exchange BioTechniques. Nov, 2013 | Pubmed ID: 24215638 TERT Promoter Mutations Occur Frequently in Gliomas and a Subset of Tumors Derived from Cells with Low Rates of Self-renewal Proceedings of the National Academy of Sciences of the United States of America. Apr, 2013 | Pubmed ID: 23530248 High Level of Chromosomal Aberration in Ovarian Cancer Genome Correlates with Poor Clinical Outcome Gynecologic Oncology. Mar, 2013 | Pubmed ID: 23200914 The Role of Forkhead Box Q1 Transcription Factor in Ovarian Epithelial Carcinomas International Journal of Molecular Sciences. Oct, 2012 | Pubmed ID: 23203039 Functional Analysis of In-frame Indel ARID1A Mutations Reveals New Regulatory Mechanisms of Its Tumor Suppressor Functions Neoplasia (New York, N.Y.). Oct, 2012 | Pubmed ID: 23097632 Mapping DNA Quantity into Electrophoretic Mobility Through Quantum Dot Nanotethers for High-Resolution Genetic and Epigenetic Analysis ACS Nano. Jan, 2012 | Pubmed ID: 22136600 ARID1A, a Factor That Promotes Formation of SWI/SNF-mediated Chromatin Remodeling, is a Tumor Suppressor in Gynecologic Cancers Cancer Research. Nov, 2011 | Pubmed ID: 21900401 Mutation of PPP2R1A: a New Clue in Unveiling the Pathogenesis of Uterine Serous Carcinoma The Journal of Pathology. May, 2011 | Pubmed ID: 21432855 Mutation and Loss of Expression of ARID1A in Uterine Low-grade Endometrioid Carcinoma The American Journal of Surgical Pathology. May, 2011 | Pubmed ID: 21412130 Molecular Genetic Markers in Female Reproductive Cancers Journal of Oncology. 2010 | Pubmed ID: 21541207 Distinct DNA Methylation Profiles in Ovarian Serous Neoplasms and Their Implications in Ovarian Carcinogenesis American Journal of Obstetrics and Gynecology. Dec, 2010 | Pubmed ID: 20965493 DNA Copy Numbers Profiles in Affinity-purified Ovarian Clear Cell Carcinoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2010 | Pubmed ID: 20233889 Utility of P16 Expression for Distinction of Uterine Serous Carcinomas from Endometrial Endometrioid and Endocervical Adenocarcinomas: Immunohistochemical Analysis of 201 Cases The American Journal of Surgical Pathology. Oct, 2009 | Pubmed ID: 19623034 Analysis of DNA Copy Number Alterations in Ovarian Serous Tumors Identifies New Molecular Genetic Changes in Low-grade and High-grade Carcinomas Cancer Research. May, 2009 | Pubmed ID: 19383911 Digital Karyotyping: an Update of Its Applications in Cancer Molecular Diagnosis & Therapy. 2006 | Pubmed ID: 16884326 Amplification of a Chromatin Remodeling Gene, Rsf-1/HBXAP, in Ovarian Carcinoma Proceedings of the National Academy of Sciences of the United States of America. Sep, 2005 | Pubmed ID: 16172393 Activation of Mitogen-activated Protein Kinase is Required for Migration and Invasion of Placental Site Trophoblastic Tumor The American Journal of Pathology. Sep, 2005 | Pubmed ID: 16127165 Patterns of P53 Mutations Separate Ovarian Serous Borderline Tumors and Low- and High-grade Carcinomas and Provide Support for a New Model of Ovarian Carcinogenesis: a Mutational Analysis with Immunohistochemical Correlation The American Journal of Surgical Pathology. Feb, 2005 | Pubmed ID: 15644779 Three Classes of Genes Mutated in Colorectal Cancers with Chromosomal Instability Cancer Research. May, 2004 | Pubmed ID: 15126332 Non-Invasive Ultrasound Assessment of Endometrial Cancer Progression in Pax8-Directed Deletion of the Tumor Suppressors Arid1a and Pten in Mice Rachel Vistein1, Briana Winer2, Stephanie Myers1,3, Juliane Liberto4, Shun Ishiyama1,5,6, Xin Guo1, Harumi Saeki7, Tian-Li Wang4,8, Ie-Ming Shih2,4,8, Kathleen Gabrielson1,4,8 1Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, 2Department of Obstetrics and Gynecology, Johns Hopkins University School of Medicine, 3Texas Tech University School of Veterinary Medicine, 4Department of Pathology, Johns Hopkins University School of Medicine, 5Department of Surgery, Johns Hopkins University School of Medicine, 6Department of Coloproctological Surgery, Juntendo University School of Medicine, 7Department of Human Pathology, Juntendo University School of Medicine, 8Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University JoVE 64732 Pesquisa do câncer
Non-Invasive Ultrasound Assessment of Endometrial Cancer Progression in Pax8-Directed Deletion of the Tumor Suppressors Arid1a and Pten in Mice Rachel Vistein1, Briana Winer2, Stephanie Myers1,3, Juliane Liberto4, Shun Ishiyama1,5,6, Xin Guo1, Harumi Saeki7, Tian-Li Wang4,8, Ie-Ming Shih2,4,8, Kathleen Gabrielson1,4,8 1Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, 2Department of Obstetrics and Gynecology, Johns Hopkins University School of Medicine, 3Texas Tech University School of Veterinary Medicine, 4Department of Pathology, Johns Hopkins University School of Medicine, 5Department of Surgery, Johns Hopkins University School of Medicine, 6Department of Coloproctological Surgery, Juntendo University School of Medicine, 7Department of Human Pathology, Juntendo University School of Medicine, 8Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University JoVE 64732 Pesquisa do câncer