Tomoko Betsuyaku Division of Pulmonary Medicine Keio University School of Medicine Biography Publications Institution JoVE Articles Tomoko Betsuyaku has not added a biography. If you are Tomoko Betsuyaku and would like to personalize this page please email our Author Liaison for assistance. Publications The Association Between Dental Health and Nutritional Status in Chronic Obstructive Pulmonary Disease Chronic Respiratory Disease. Apr, 2016 | Pubmed ID: 27056058 Mechanisms to Suppress ILC2-induced Airway Inflammation Annals of the American Thoracic Society. Mar, 2016 | Pubmed ID: 27027961 Disseminated Mycobacterium Marinum Infection With a Destructive Nasal Lesion Mimicking Extranodal NK/T Cell Lymphoma: A Case Report Medicine. Mar, 2016 | Pubmed ID: 26986167 Determinants of Chronic Obstructive Pulmonary Disease Severity in the Late-elderly Differ from Those in Younger Patients BMC Research Notes. 2016 | Pubmed ID: 26728686 Activation of EGFR Bypass Signaling by TGFα Overexpression Induces Acquired Resistance to Alectinib in ALK-Translocated Lung Cancer Cells Molecular Cancer Therapeutics. Jan, 2016 | Pubmed ID: 26682573 Interferon and IL-27 Antagonize the Function of Group 2 Innate Lymphoid Cells and Type 2 Innate Immune Responses Nature Immunology. Jan, 2016 | Pubmed ID: 26595888 Pneumococcal Infection Aggravates Elastase-Induced Emphysema Via Matrix Metalloproteinase 12 Overexpression The Journal of Infectious Diseases. Mar, 2016 | Pubmed ID: 26563237 Blue-Black Trachea As a Result of Minocycline-induced Hyperpigmentation American Journal of Respiratory and Critical Care Medicine. Feb, 2016 | Pubmed ID: 26426678 Theory and Strategy for Pneumococcal Vaccines in the Elderly Human Vaccines & Immunotherapeutics. Feb, 2016 | Pubmed ID: 26406267 Fournier's Gangrene: a Surgical Emergency Infection. Feb, 2016 | Pubmed ID: 26138056 Levels of Soluble Receptor for Advanced Glycation End Products in Bronchoalveolar Lavage Fluid in Patients with Various Inflammatory Lung Diseases Clinical Medicine Insights. Circulatory, Respiratory and Pulmonary Medicine. 2015 | Pubmed ID: 27147899 Health-related Quality of Life is Inversely Correlated with C-reactive Protein and Age in Mycobacterium Avium Complex Lung Disease: a Cross-sectional Analysis of 235 Patients Respiratory Research. 2015 | Pubmed ID: 26635226 The Chronic Obstructive Pulmonary Disease Comorbidity Spectrum in Japan Differs from That in Western Countries Respiratory Investigation. Nov, 2015 | Pubmed ID: 26521103 In Vitro Modeling to Determine Mutation Specificity of EGFR Tyrosine Kinase Inhibitors Against Clinically Relevant EGFR Mutants in Non-small-cell Lung Cancer Oncotarget. Nov, 2015 | Pubmed ID: 26515464 Dry Pleurisy Complicating Solitary Pulmonary Nodules Caused by Mycobacterium Avium: a Case Report Journal of Medical Case Reports. 2015 | Pubmed ID: 26503229 Successful Resumption of Tocilizumab for Rheumatoid Arthritis After Resection of a Pulmonary Mycobacterium Avium Complex Lesion: a Case Report BMC Pulmonary Medicine. 2015 | Pubmed ID: 26496968 Distinct Effects of Endogenous Interleukin-23 on Eosinophilic Airway Inflammation in Response to Different Antigens Allergology International : Official Journal of the Japanese Society of Allergology. Sep, 2015 | Pubmed ID: 26344076 Immune Reconstitution Inflammatory Syndrome Due to Mycobacterium Avium Complex Successfully Followed Up Using 18 F-fluorodeoxyglucose Positron Emission Tomography-computed Tomography in a Patient with Human Immunodeficiency Virus Infection: A Case Report BMC Medical Imaging. 2015 | Pubmed ID: 26187282 Fatal Fulminant Pneumonia Caused by Methicillin-Sensitive Staphylococcus Aureus Negative for Major High-Virulence Factors Following Influenza B Virus Infection The American Journal of Case Reports. 2015 | Pubmed ID: 26171835 Prognostic Implication of PTPRH Hypomethylation in Non-small Cell Lung Cancer Oncology Reports. Sep, 2015 | Pubmed ID: 26134684 A Case of Disseminated Cryptococcal Infection and Concurrent Lung Tuberculosis in a Patient Under Steroid Therapy for Interstitial Pneumonia Case Reports in Pulmonology. 2015 | Pubmed ID: 26124974 The Reasons for Triple Therapy in Stable COPD Patients in Japanese Clinical Practice International Journal of Chronic Obstructive Pulmonary Disease. 2015 | Pubmed ID: 26082629 Mimicking the Niche of Lung Epithelial Stem Cells and Characterization of Several Effectors of Their in Vitro Behavior Stem Cell Research. Jul, 2015 | Pubmed ID: 26042794 Correlation of a Decline in Aerobic Capacity with Development of Emphysema in Patients with Chronic Obstructive Pulmonary Disease: a Prospective Observational Study PloS One. 2015 | Pubmed ID: 25909949 Attenuation of Lipopolysaccharide-induced Acute Lung Injury After (pro)renin Receptor Blockade Experimental Lung Research. May, 2015 | Pubmed ID: 25844689 Phenotype of Asthma Related with High Serum Periostin Levels Allergology International : Official Journal of the Japanese Society of Allergology. Apr, 2015 | Pubmed ID: 25838094 Evaluation of Cigarette Smoke-induced Emphysema in Mice Using Quantitative Micro-computed Tomography American Journal of Physiology. Lung Cellular and Molecular Physiology. May, 2015 | Pubmed ID: 25820526 The Diagnostic Usefulness of 18F-fluorodoxyglucose-positron Emission Tomography/CT in SAPHO Syndrome BMJ Case Reports. 2015 | Pubmed ID: 25733097 A Phase II Study of S-1 and Irinotecan Combination Therapy in Previously Treated Patients with Advanced Non-small Cell Lung Cancer Japanese Journal of Clinical Oncology. Apr, 2015 | Pubmed ID: 25612761 A Phase II Study of Biweekly Paclitaxel and Carboplatin in Elderly Patients with Advanced Non-small Cell Lung Cancer Cancer Chemotherapy and Pharmacology. Mar, 2015 | Pubmed ID: 25563719 FOXD1 Expression is Associated with Poor Prognosis in Non-small Cell Lung Cancer Anticancer Research. Jan, 2015 | Pubmed ID: 25550559 Comparison of the Immunogenicity and Safety of Polysaccharide and Protein-conjugated Pneumococcal Vaccines Among the Elderly Aged 80 Years or Older in Japan: an Open-labeled Randomized Study Vaccine. Jan, 2015 | Pubmed ID: 25448102 Methylation-induced Downregulation of TFPI-2 Causes TMPRSS4 Overexpression and Contributes to Oncogenesis in a Subset of Non-small-cell Lung Carcinoma Cancer Science. Jan, 2015 | Pubmed ID: 25414083 Characterization of the Cell of Origin and Propagation Potential of the Fibroblast Growth Factor 9-induced Mouse Model of Lung Adenocarcinoma The Journal of Pathology. Mar, 2015 | Pubmed ID: 25413587 Polymorphism of LRP5 Gene and Emphysema Severity Are Associated with Osteoporosis in Japanese Patients with or at Risk for COPD Respirology (Carlton, Vic.). Feb, 2015 | Pubmed ID: 25392953 Long‑term Exposure to Gefitinib Induces Acquired Resistance Through DNA Methylation Changes in the EGFR‑mutant PC9 Lung Cancer Cell Line International Journal of Oncology. Jan, 2015 | Pubmed ID: 25353970 Multiple Roles of Extracellular Fibroblast Growth Factors in Lung Cancer Cells International Journal of Oncology. Jan, 2015 | Pubmed ID: 25353145 Determinants of Long-Term Persistence with Tiotropium Bromide for Chronic Obstructive Pulmonary Disease COPD. Jun, 2015 | Pubmed ID: 25093464 Pulmonary Nocardiosis Caused by Nocardia Cyriacigeorgica in Patients with Mycobacterium Avium Complex Lung Disease: Two Case Reports BMC Infectious Diseases. 2014 | Pubmed ID: 25491030 Serum (1 → 3) β-D-glucan Assay for Discrimination Between Pneumocystis Jirovecii Pneumonia and Colonization Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy. Nov, 2014 | Pubmed ID: 25066434 Claudin-1 is a Novel Target of MiR-375 in Non-small-cell Lung Cancer Lung Cancer (Amsterdam, Netherlands). Sep, 2014 | Pubmed ID: 25001509 Pharmacokinetics of Arbekacin in Bronchial Epithelial Lining Fluid of Healthy Volunteers Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy. Oct, 2014 | Pubmed ID: 24973909 Epigenetic Clustering of Lung Adenocarcinomas Based on DNA Methylation Profiles in Adjacent Lung Tissue: Its Correlation with Smoking History and Chronic Obstructive Pulmonary Disease International Journal of Cancer. Jul, 2014 | Pubmed ID: 24921089 Plasma Cytokine Profiles Related to Smoking-sensitivity and Phenotypes of Chronic Obstructive Pulmonary Disease Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. Aug, 2014 | Pubmed ID: 24842387 Dual Role of Interleukin-23 in Epicutaneously-sensitized Asthma in Mice Allergology International : Official Journal of the Japanese Society of Allergology. May, 2014 | Pubmed ID: 24809371 The Efficacy, Safety, and Pharmacokinetics of Biapenem Administered Thrice Daily for the Treatment of Pneumonia in the Elderly Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy. Jun, 2014 | Pubmed ID: 24725621 Analysis of Comorbid Factors That Increase the COPD Assessment Test Scores Respiratory Research. 2014 | Pubmed ID: 24502760 Combination Therapy of 15-epi-lipoxin A4 with Antibiotics Protects Mice from Escherichia Coli-induced Sepsis* Critical Care Medicine. Apr, 2014 | Pubmed ID: 24463858 Lung Natural Killer Cells Play a Major Counter-regulatory Role in Pulmonary Vascular Hyperpermeability After Myocardial Infarction Circulation Research. Feb, 2014 | Pubmed ID: 24366170 Expression of Fibroblast Growth Factor 9 is Associated with Poor Prognosis in Patients with Resected Non-small Cell Lung Cancer Lung Cancer (Amsterdam, Netherlands). Jan, 2014 | Pubmed ID: 24239165 A Case of Skeletal Tuberculosis and Psoas Abscess: Disease Activity Evaluated Using (18) F-fluorodeoxyglucose Positron Emission Tomography-computed Tomography BMC Medical Imaging. 2013 | Pubmed ID: 24225333 Modulation of Murine Macrophage TLR7/8-mediated Cytokine Expression by Mesenchymal Stem Cell-conditioned Medium Mediators of Inflammation. 2013 | Pubmed ID: 24191131 Thymic Stromal Lymphopoietin Induces Corticosteroid Resistance in Natural Helper Cells During Airway Inflammation Nature Communications. 2013 | Pubmed ID: 24157859 A Study to Assess COPD Symptom-based Management and to Optimise Treatment Strategy in Japan (COSMOS-J) Based on GOLD 2011 International Journal of Chronic Obstructive Pulmonary Disease. 2013 | Pubmed ID: 24124358 Rapid Induction of Lung Adenocarcinoma by Fibroblast Growth Factor 9 Signaling Through FGF Receptor 3 Cancer Research. Sep, 2013 | Pubmed ID: 23867472 A Single Dose of Lipopolysaccharide into Mice with Emphysema Mimics Human Chronic Obstructive Pulmonary Disease Exacerbation As Assessed by Micro-computed Tomography American Journal of Respiratory Cell and Molecular Biology. Dec, 2013 | Pubmed ID: 23822858 [Case Report; A Case of Acute Respiratory Failure Following Influenza Virus Infection Successfully Treated by Direct Hemoperfusion Using a Polymyxin B Immobilized Fiber Column] Nihon Naika Gakkai Zasshi. The Journal of the Japanese Society of Internal Medicine. Feb, 2013 | Pubmed ID: 23767322 Identification of MicroRNAs Differentially Expressed Between Lung Squamous Cell Carcinoma and Lung Adenocarcinoma Molecular Medicine Reports. Aug, 2013 | Pubmed ID: 23759980 Distinguishing Between Lymphangioleiomyomatosis and Carcinomatous Peritonitis in a Patient with Ovarian Cancer Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Oct, 2013 | Pubmed ID: 23752115 Bone Morphogenetic Protein Receptor Type 2 Mutations, Clinical Phenotypes and Outcomes of Japanese Patients with Sporadic or Familial Pulmonary Hypertension Respirology (Carlton, Vic.). Oct, 2013 | Pubmed ID: 23675998 DNA Methylation Profiles at Precancerous Stages Associated with Recurrence of Lung Adenocarcinoma PloS One. 2013 | Pubmed ID: 23544068 Activation of the FGF2-FGFR1 Autocrine Pathway: a Novel Mechanism of Acquired Resistance to Gefitinib in NSCLC Molecular Cancer Research : MCR. Jul, 2013 | Pubmed ID: 23536707 Bacillus Cereus Necrotizing Pneumonia in a Patient with Nephrotic Syndrome Internal Medicine (Tokyo, Japan). 2013 | Pubmed ID: 23291682 Bronchiolar Epithelial Catalase is Diminished in Smokers with Mild COPD The European Respiratory Journal. Jul, 2013 | Pubmed ID: 23100509 Dysregulated Synthesis of Protectin D1 in Eosinophils from Patients with Severe Asthma The Journal of Allergy and Clinical Immunology. Feb, 2013 | Pubmed ID: 23006546 Tuberous Sclerosis Diagnosed by Incidental Computed Tomography Findings of Multifocal Micronodular Pneumocyte Hyperplasia: a Case Report Journal of Medical Case Reports. 2012 | Pubmed ID: 23072249 α1,6-Fucosyltransferase (Fut8) is Implicated in Vulnerability to Elastase-induced Emphysema in Mice and a Possible Non-invasive Predictive Marker for Disease Progression and Exacerbations in Chronic Obstructive Pulmonary Disease (COPD) Biochemical and Biophysical Research Communications. Jul, 2012 | Pubmed ID: 22732410 CRTH2 is a Critical Regulator of Neutrophil Migration and Resistance to Polymicrobial Sepsis Journal of Immunology (Baltimore, Md. : 1950). Jun, 2012 | Pubmed ID: 22544936 Cytokine Profile of Bronchoalveolar Lavage Fluid in Patients with Combined Pulmonary Fibrosis and Emphysema Respirology (Carlton, Vic.). Jul, 2012 | Pubmed ID: 22515655 Predictors of Osteoporosis and Vertebral Fractures in Patients Presenting with Moderate-to-severe Chronic Obstructive Lung Disease COPD. Aug, 2012 | Pubmed ID: 22489911 Sensitivity of Heterozygous α1,6-fucosyltransferase Knock-out Mice to Cigarette Smoke-induced Emphysema: Implication of Aberrant Transforming Growth Factor-β Signaling and Matrix Metalloproteinase Gene Expression The Journal of Biological Chemistry. May, 2012 | Pubmed ID: 22433854 [A Case of Elderly Advanced Squamous Cell Lung Carcinoma Successfully Treated with Nedaplatin and S-1 Combination Chemotherapy] Gan to Kagaku Ryoho. Cancer & Chemotherapy. Mar, 2012 | Pubmed ID: 22421773 Roles of Interleukin-17 in an Experimental Legionella Pneumophila Pneumonia Model Infection and Immunity. Mar, 2012 | Pubmed ID: 22144493 Annual Change in Pulmonary Function and Clinical Phenotype in Chronic Obstructive Pulmonary Disease American Journal of Respiratory and Critical Care Medicine. Jan, 2012 | Pubmed ID: 22016444 Neutrophil Elastase Cleaves the Murine Hemidesmosomal Protein BP180/type XVII Collagen and Generates Degradation Products That Modulate Experimental Bullous Pemphigoid Matrix Biology : Journal of the International Society for Matrix Biology. Jan, 2012 | Pubmed ID: 21979170 Beta2-adrenergic Receptor Polymorphisms As a Determinant of Preferential Bronchodilator Responses to β2-agonist and Anticholinergic Agents in Japanese Patients with Chronic Obstructive Pulmonary Disease Pharmacogenetics and Genomics. Nov, 2011 | Pubmed ID: 21881540 The Role of Matrix Metalloproteinase-9 in Cigarette Smoke-induced Emphysema American Journal of Respiratory and Critical Care Medicine. Apr, 2011 | Pubmed ID: 21057003 The Role of Catalase in Pulmonary Fibrosis Respiratory Research. 2010 | Pubmed ID: 21190578 Met behulp van micro-computertomografie voor de evaluatie van de ontwikkeling van tumoren en follow-up van de respons op de behandeling in een muismodel van longkanker Ahmed E. Hegab1, Naofumi Kameyama1, Aoi Kuroda1, Shizuko Kagawa1, Yongjun Yin2, David Ornitz2, Tomoko Betsuyaku1 1Division of Pulmonary Medicine, Keio University School of Medicine, 2Department of Developmental Biology, Washington University School of Medicine Medicina
Met behulp van micro-computertomografie voor de evaluatie van de ontwikkeling van tumoren en follow-up van de respons op de behandeling in een muismodel van longkanker Ahmed E. Hegab1, Naofumi Kameyama1, Aoi Kuroda1, Shizuko Kagawa1, Yongjun Yin2, David Ornitz2, Tomoko Betsuyaku1 1Division of Pulmonary Medicine, Keio University School of Medicine, 2Department of Developmental Biology, Washington University School of Medicine Medicina