Toshiaki Kawakami Division of Cell Biology La Jolla Institute for Allergy and Immunology Biography Publications Institution JoVE Articles Toshiaki Kawakami has not added a biography. If you are Toshiaki Kawakami and would like to personalize this page please email our Author Liaison for assistance. Publications Kimishige Ishizaka 1925-2018 Nature Immunology. Sep, 2018 | Pubmed ID: 30104631 PAI1 Mediates Fibroblast-mast Cell Interactions in Skin Fibrosis The Journal of Clinical Investigation. May, 2018 | Pubmed ID: 29584619 LIGHT-HVEM Signaling in Keratinocytes Controls Development of Dermatitis The Journal of Experimental Medicine. Feb, 2018 | Pubmed ID: 29339444 Crystal Structures of Murine and Human Histamine-Releasing Factor (HRF/TCTP) and a Model for HRF Dimerisation in Mast Cell Activation Molecular Immunology. Jan, 2018 | Pubmed ID: 29216544 Histamine-releasing Factor Enhances Food Allergy The Journal of Clinical Investigation. Dec, 2017 | Pubmed ID: 29130935 TWEAK Mediates Inflammation in Experimental Atopic Dermatitis and Psoriasis Nature Communications. May, 2017 | Pubmed ID: 28530223 Role of Histamine-releasing Factor in Allergic Inflammatory Reactions Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan. 2017 | Pubmed ID: 28458281 Skin Microbiome Promotes Mast Cell Maturation by Triggering Stem Cell Factor Production in Keratinocytes The Journal of Allergy and Clinical Immunology. Apr, 2017 | Pubmed ID: 27746235 Defective Natural Killer Cell Activity in a Mouse Model of Eczema Herpeticum The Journal of Allergy and Clinical Immunology. Mar, 2017 | Pubmed ID: 27476888 From IgE to Omalizumab Journal of Immunology (Baltimore, Md. : 1950). 12, 2016 | Pubmed ID: 27864548 Guanine Nucleotide Exchange Factor RABGEF1 Regulates Keratinocyte-intrinsic Signaling to Maintain Skin Homeostasis The Journal of Clinical Investigation. Dec, 2016 | Pubmed ID: 27820702 Differentiate or Die! Nature Immunology. 08, 2016 | Pubmed ID: 27540982 Signal Transduction and Chemotaxis in Mast Cells European Journal of Pharmacology. May, 2016 | Pubmed ID: 25941081 Hypothetical Atopic Dermatitis-Myeloproliferative Neoplasm Syndrome Frontiers in Immunology. 2015 | Pubmed ID: 26379670 Mast Cells and Dendritic Cells Form Synapses That Facilitate Antigen Transfer for T Cell Activation The Journal of Cell Biology. Aug, 2015 | Pubmed ID: 26304724 A Mouse Model of Atopic Dermatitis Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 25388270 Basic Techniques to Study FcεRI Signaling in Mast Cells Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 25388253 Critical Role for Mast Cell Stat5 Activity in Skin Inflammation Cell Reports. Jan, 2014 | Pubmed ID: 24412367 Histamine-releasing Factor and Immunoglobulins in Asthma and Allergy Allergy, Asthma & Immunology Research. Jan, 2014 | Pubmed ID: 24404387 Salmonella's Masterful Skill in Mast Cell Suppression Immunity. Dec, 2013 | Pubmed ID: 24332026 Phospholipase C-β in Immune Cells Advances in Biological Regulation. Sep, 2013 | Pubmed ID: 23981313 Mast Cells Are Required for Full Expression of Allergen/SEB-induced Skin Inflammation The Journal of Investigative Dermatology. Dec, 2013 | Pubmed ID: 23752044 Most Highly Cytokinergic IgEs Have Polyreactivity to Autoantigens Allergy, Asthma & Immunology Research. Nov, 2012 | Pubmed ID: 23115729 A Novel Role for the Transcription Factor HIF-1α in the Formation of Mast Cell Extracellular Traps The Biochemical Journal. Aug, 2012 | Pubmed ID: 22738198 Human FcγRIIA at Center Stage Blood. Mar, 2012 | Pubmed ID: 22422810 Histamine-releasing Factor Has a Proinflammatory Role in Mouse Models of Asthma and Allergy The Journal of Clinical Investigation. Jan, 2012 | Pubmed ID: 22133880 Regulation of Proliferation, Survival, Differentiation, and Activation by the Signaling Platform for SHP-1 Phosphatase Advances in Biological Regulation. Jan, 2012 | Pubmed ID: 21982978 Short Stat5-interacting Peptide Derived from Phospholipase C-β3 Inhibits Hematopoietic Cell Proliferation and Myeloid Differentiation PloS One. 2011 | Pubmed ID: 21949826 IgE Stimulates Human and Mouse Arterial Cell Apoptosis and Cytokine Expression and Promotes Atherogenesis in Apoe-/- Mice The Journal of Clinical Investigation. Sep, 2011 | Pubmed ID: 21821913 Monomeric IgE and Mast Cell Development, Survival and Function Advances in Experimental Medicine and Biology. 2011 | Pubmed ID: 21713650 Phospholipase C-β3 Regulates FcɛRI-mediated Mast Cell Activation by Recruiting the Protein Phosphatase SHP-1 Immunity. Jun, 2011 | Pubmed ID: 21683628 Protective Murine and Human Monoclonal Antibodies Against Eczema Vaccinatum Antiviral Therapy. 2011 | Pubmed ID: 21311110 JNK1 Controls Mast Cell Degranulation and IL-1{beta} Production in Inflammatory Arthritis Proceedings of the National Academy of Sciences of the United States of America. Dec, 2010 | Pubmed ID: 21135226 Lyn- and PLC-beta3-dependent Regulation of SHP-1 Phosphorylation Controls Stat5 Activity and Myelomonocytic Leukemia-like Disease Blood. Dec, 2010 | Pubmed ID: 20858858 A Minor Catalytic Activity of Src Family Kinases is Sufficient for Maximal Activation of Mast Cells Via the High-affinity IgE Receptor Journal of Immunology (Baltimore, Md. : 1950). Jan, 2010 | Pubmed ID: 19949072 A Crucial Door to the Mast Cell Mystery Knocked In Journal of Immunology (Baltimore, Md. : 1950). Dec, 2009 | Pubmed ID: 19923472 Mast Cells in Atopic Dermatitis Current Opinion in Immunology. Dec, 2009 | Pubmed ID: 19828304 Small, Mobile FcepsilonRI Receptor Aggregates Are Signaling Competent Immunity. Sep, 2009 | Pubmed ID: 19747859 Tumor Suppression by Phospholipase C-beta3 Via SHP-1-mediated Dephosphorylation of Stat5 Cancer Cell. Aug, 2009 | Pubmed ID: 19647226 Polyclonal IgE Induces Mast Cell Survival and Cytokine Production Allergology International : Official Journal of the Japanese Society of Allergology. Sep, 2009 | Pubmed ID: 19542764 Inhibition of NK Cell Activity by IL-17 Allows Vaccinia Virus to Induce Severe Skin Lesions in a Mouse Model of Eczema Vaccinatum The Journal of Experimental Medicine. Jun, 2009 | Pubmed ID: 19468065 Allergen-independent Immunomodulatory Activities of Immunoglobulin E Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology. Mar, 2009 | Pubmed ID: 19178542 Pivotal Advance: IgE Accelerates in Vitro Development of Mast Cells and Modifies Their Phenotype Journal of Leukocyte Biology. Aug, 2008 | Pubmed ID: 18477690 Regulation of Myeloproliferation and M2 Macrophage Programming in Mice by Lyn/Hck, SHIP, and Stat5 The Journal of Clinical Investigation. Mar, 2008 | Pubmed ID: 18246197 An Improved Mouse Model of Atopic Dermatitis and Suppression of Skin Lesions by an Inhibitor of Tec Family Kinases Allergology International : Official Journal of the Japanese Society of Allergology. Dec, 2007 | Pubmed ID: 17713360 The Src Family Kinase Hck Regulates Mast Cell Activation by Suppressing an Inhibitory Src Family Kinase Lyn Blood. Oct, 2007 | Pubmed ID: 17513616 Dysregulation of Src Family Kinases in Mast Cells from Epilepsy-resistant ASK Versus Epilepsy-prone EL Mice Journal of Immunology (Baltimore, Md. : 1950). Jan, 2007 | Pubmed ID: 17182584 Development, Migration, and Survival of Mast Cells Immunologic Research. 2006 | Pubmed ID: 16760571 Regulation of Dendritic Cell Maturation and Function by Bruton's Tyrosine Kinase Via IL-10 and Stat3 Proceedings of the National Academy of Sciences of the United States of America. Jan, 2006 | Pubmed ID: 16371463 Techniques to Study Fc EpsilonRI Signaling Methods in Molecular Biology (Clifton, N.J.). 2006 | Pubmed ID: 16110158 IgE Regulation of Mast Cell Survival and Function Novartis Foundation Symposium. 2005 | Pubmed ID: 16605130 Positive and Negative Regulation of Mast Cell Activation by Lyn Via the FcepsilonRI Journal of Immunology (Baltimore, Md. : 1950). Nov, 2005 | Pubmed ID: 16272347 Mast Cell Survival and Activation by IgE in the Absence of Antigen: a Consideration of the Biologic Mechanisms and Relevance Journal of Immunology (Baltimore, Md. : 1950). Oct, 2005 | Pubmed ID: 16177053 Costimulation of Mast Cells by 4-1BB, a Member of the Tumor Necrosis Factor Receptor Superfamily, with the High-affinity IgE Receptor Blood. Dec, 2005 | Pubmed ID: 16123219 Regulation of Highly Cytokinergic IgE-induced Mast Cell Adhesion by Src, Syk, Tec, and Protein Kinase C Family Kinases Journal of Immunology (Baltimore, Md. : 1950). Apr, 2005 | Pubmed ID: 15814670 IgE- and IgE+Ag-mediated Mast Cell Migration in an Autocrine/paracrine Fashion Blood. Apr, 2005 | Pubmed ID: 15637135 Critical Role for Galectin-3 in Airway Inflammation and Bronchial Hyperresponsiveness in a Murine Model of Asthma The American Journal of Pathology. Dec, 2004 | Pubmed ID: 15579447 Early Divergence of Fc Epsilon Receptor I Signals for Receptor Up-regulation and Internalization from Degranulation, Cytokine Production, and Survival Journal of Immunology (Baltimore, Md. : 1950). Oct, 2004 | Pubmed ID: 15383560 Protein Kinase C BetaII Regulates Akt Phosphorylation on Ser-473 in a Cell Type- and Stimulus-specific Fashion The Journal of Biological Chemistry. Nov, 2004 | Pubmed ID: 15364915 [Regulation of Mast Cell Survival and Activation by Monomeric IgE] Arerugi = [Allergy]. Jun, 2004 | Pubmed ID: 15247516 Evidence That IgE Molecules Mediate a Spectrum of Effects on Mast Cell Survival and Activation Via Aggregation of the FcepsilonRI Proceedings of the National Academy of Sciences of the United States of America. Oct, 2003 | Pubmed ID: 14569021 A Ras Activation Pathway Dependent on Syk Phosphorylation of Protein Kinase C Proceedings of the National Academy of Sciences of the United States of America. Aug, 2003 | Pubmed ID: 12881490 Protein Kinase C Beta (PKC Beta): Normal Functions and Diseases Journal of Biochemistry. Nov, 2002 | Pubmed ID: 12417015 Regulation of Mast-cell and Basophil Function and Survival by IgE Nature Reviews. Immunology. Oct, 2002 | Pubmed ID: 12360215 PKCbeta Modulates Antigen Receptor Signaling Via Regulation of Btk Membrane Localization The EMBO Journal. Oct, 2001 | Pubmed ID: 11598012 Akt-dependent Cytokine Production in Mast Cells The Journal of Experimental Medicine. Sep, 2000 | Pubmed ID: 10974038 Regulation of Protein Kinase CbetaI by Two Protein-tyrosine Kinases, Btk and Syk Proceedings of the National Academy of Sciences of the United States of America. Jun, 2000 | Pubmed ID: 10852954 Terreic Acid, a Quinone Epoxide Inhibitor of Bruton's Tyrosine Kinase Proceedings of the National Academy of Sciences of the United States of America. Mar, 1999 | Pubmed ID: 10051623 Involvement of Bruton's Tyrosine Kinase in FcepsilonRI-dependent Mast Cell Degranulation and Cytokine Production The Journal of Experimental Medicine. Apr, 1998 | Pubmed ID: 9547335 Bruton's Tyrosine Kinase Regulates Apoptosis and JNK/SAPK Kinase Activity Proceedings of the National Academy of Sciences of the United States of America. Apr, 1997 | Pubmed ID: 9108083 Kızılötesi termometre pasif sistemik anafilaksi ve gıda Anti değerlendirme sırasında kullanarak fare vücut sıcaklık ölçümü Yu Kawakami1, Rachel Sielski1, Toshiaki Kawakami1 1Division of Cell Biology, La Jolla Institute for Allergy and Immunology JoVE 58391 Imunologia e Infecção
Kızılötesi termometre pasif sistemik anafilaksi ve gıda Anti değerlendirme sırasında kullanarak fare vücut sıcaklık ölçümü Yu Kawakami1, Rachel Sielski1, Toshiaki Kawakami1 1Division of Cell Biology, La Jolla Institute for Allergy and Immunology JoVE 58391 Imunologia e Infecção