Wayne A. Fenton

Publications

• Molecular Chaperone Hsp110 Rescues a Vesicle Transport Defect Produced by an ALS-associated Mutant SOD1 Protein in Squid Axoplasm
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2013  |   Pubmed ID: 23509252
• RNA-Seq Profiling of Spinal Cord Motor Neurons from a Presymptomatic SOD1 ALS Mouse
  PloS One. 2013  |   Pubmed ID: 23301088
• Structure and Allostery of the Chaperonin GroEL
  Journal of Molecular Biology. May, 2013  |   Pubmed ID: 23183375
• Hydrogen-deuterium Exchange in Vivo to Measure Turnover of an ALS-associated Mutant SOD1 Protein in Spinal Cord of Mice
  Protein Science : a Publication of the Protein Society. Oct, 2011  |   Pubmed ID: 21780215
• Double Mutant MBP Refolds at Same Rate in Free Solution As Inside the GroEL/GroES Chaperonin Chamber when Aggregation in Free Solution is Prevented
  FEBS Letters. Jun, 2011  |   Pubmed ID: 21609718
• ATP-triggered ADP Release from the Asymmetric Chaperonin GroEL/GroES/ADP7 is Not the Rate-limiting Step of the GroEL/GroES Reaction Cycle
  FEBS Letters. Mar, 2010  |   Pubmed ID: 20083109
• GroEL/GroES Cycling: ATP Binds to an Open Ring Before Substrate Protein Favoring Protein Binding and Production of the Native State
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2009  |   Pubmed ID: 19915138
• Chaperonin-mediated Protein Folding: Using a Central Cavity to Kinetically Assist Polypeptide Chain Folding
  Quarterly Reviews of Biophysics. May, 2009  |   Pubmed ID: 19638247
• The GroEL/GroES Cis Cavity As a Passive Anti-aggregation Device
  FEBS Letters. Aug, 2009  |   Pubmed ID: 19577567
• Requirement for Binding Multiple ATPs to Convert a GroEL Ring to the Folding-active State
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2008  |   Pubmed ID: 19050077
• Folding Trajectories of Human Dihydrofolate Reductase Inside the GroEL GroES Chaperonin Cavity and Free in Solution
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2007  |   Pubmed ID: 18093916
• Two Families of Chaperonin: Physiology and Mechanism
  Annual Review of Cell and Developmental Biology. 2007  |   Pubmed ID: 17489689
• Perturbed ATPase Activity and Not "close Confinement" of Substrate in the Cis Cavity Affects Rates of Folding by Tail-multiplied GroEL
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2007  |   Pubmed ID: 17372195
• Disulfide Formation As a Probe of Folding in GroEL-GroES Reveals Correct Formation of Long-range Bonds and Editing of Incorrect Short-range Ones
  Proceedings of the National Academy of Sciences of the United States of America. Feb, 2007  |   Pubmed ID: 17283341
• Global Aggregation of Newly Translated Proteins in an Escherichia Coli Strain Deficient of the Chaperonin GroEL
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2006  |   Pubmed ID: 17043235
• GroEL-GroES-mediated Protein Folding
  Chemical Reviews. May, 2006  |   Pubmed ID: 16683761
• Roles of the N-domains of the ClpA Unfoldase in Binding Substrate Proteins and in Stable Complex Formation with the ClpP Protease
  The Journal of Biological Chemistry. Dec, 2005  |   Pubmed ID: 16207718
• Loops in the Central Channel of ClpA Chaperone Mediate Protein Binding, Unfolding, and Translocation
  Cell. Jul, 2005  |   Pubmed ID: 15989953
• No Evidence for a Forced-unfolding Mechanism During ATP/GroES Binding to Substrate-bound GroEL: No Observable Protection of Metastable Rubisco Intermediate or GroEL-bound Rubisco from Tritium Exchange
  FEBS Letters. Feb, 2005  |   Pubmed ID: 15710410
• Substrate Polypeptide Presents a Load on the Apical Domains of the Chaperonin GroEL
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2004  |   Pubmed ID: 15479763
• Chaperonin-mediated Protein Folding: Fate of Substrate Polypeptide
  Quarterly Reviews of Biophysics. May, 2003  |   Pubmed ID: 14686103
• Folding with and Without Encapsulation by Cis- and Trans-only GroEL-GroES Complexes
  The EMBO Journal. Jul, 2003  |   Pubmed ID: 12839985