Wolfgang W. A. Schamel Centre for Biological Signalling Studies (bioss) and Biology III, Faculty of Biology University of Freiburg Biography Publications Institution JoVE Articles Wolfgang W. A. Schamel has not added a biography. If you are Wolfgang W. A. Schamel and would like to personalize this page please email our Author Liaison for assistance. Publications A Leaky Mutation in CD3D Differentially Affects αβ and γδ T Cells and Leads to a Tαβ-Tγδ+B+NK+ Human SCID The Journal of Clinical Investigation. Oct, 2011 | Pubmed ID: 21926461 Increased Sensitivity of Antigen-experienced T Cells Through the Enrichment of Oligomeric T Cell Receptor Complexes Immunity. Sep, 2011 | Pubmed ID: 21903423 A New Vampire Saga: the Molecular Mechanism of T Cell Trogocytosis Immunity. Aug, 2011 | Pubmed ID: 21867922 Quantitative Analysis of Protein Phosphorylations and Interactions by Multi-colour IP-FCM As an Input for Kinetic Modelling of Signalling Networks PloS One. 2011 | Pubmed ID: 21829558 Pre-clustered TCR Complexes FEBS Letters. Dec, 2010 | Pubmed ID: 20828560 Innate, Antigen-independent Role for T Cells in the Activation of the Immune System by Propionibacterium Acnes European Journal of Immunology. Sep, 2010 | Pubmed ID: 20690177 Low-valency, but Not Monovalent, Antigens Trigger the B-cell Antigen Receptor (BCR) International Immunology. Mar, 2010 | Pubmed ID: 20145007 Detection of Phosphorylated T and B Cell Antigen Receptor Species by Phos-tag SDS- and Blue Native-PAGE Immunology Letters. May, 2010 | Pubmed ID: 20005898 Analysis of Novel Phospho-ITAM Specific Antibodies in a S2 Reconstitution System for TCR-CD3 Signalling Immunology Letters. May, 2010 | Pubmed ID: 20005895 Models of Antigen Receptor Activation in the Design of Vaccines Current Pharmaceutical Design. 2009 | Pubmed ID: 19860673 Target-dependent T-cell Activation by Coligation with a PSMA X CD3 Diabody Induces Lysis of Prostate Cancer Cells Journal of Immunotherapy (Hagerstown, Md. : 1997). Jul-Aug, 2009 | Pubmed ID: 19483653 Detection of Protein Complex Interactions Via a Blue Native-PAGE Retardation Assay Analytical Biochemistry. Sep, 2009 | Pubmed ID: 19482002 Purification of the T Cell Antigen Receptor and Analysis by Blue-native PAGE Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19048218 Permissive Geometry Model Advances in Experimental Medicine and Biology. 2008 | Pubmed ID: 19065789 Segregation Models Advances in Experimental Medicine and Biology. 2008 | Pubmed ID: 19065785 Clustering Models Advances in Experimental Medicine and Biology. 2008 | Pubmed ID: 19065784 Differential Antibody Binding to the Surface AlphabetaTCR.CD3 Complex of CD4+ and CD8+ T Lymphocytes is Conserved in Mammals and Associated with Differential Glycosylation International Immunology. Oct, 2008 | Pubmed ID: 18653700 Two-dimensional Blue Native Polyacrylamide Gel Electrophoresis Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [et Al.]. Mar, 2008 | Pubmed ID: 18360818 T Cell Receptor Engagement Triggers Its CD3epsilon and CD3zeta Subunits to Adopt a Compact, Locked Conformation PloS One. 2008 | Pubmed ID: 18320063 The Extracellular Part of Zeta is Buried in the T Cell Antigen Receptor Complex Immunology Letters. Mar, 2008 | Pubmed ID: 18215426 The Short Length of the Extracellular Domain of Zeta is Crucial for T Cell Antigen Receptor Function Immunology Letters. Mar, 2008 | Pubmed ID: 18207249 A Permissive Geometry Model for TCR-CD3 Activation Trends in Biochemical Sciences. Feb, 2008 | Pubmed ID: 18201888 The TCR Binding Site Does Move Proceedings of the National Academy of Sciences of the United States of America. Oct, 2007 | Pubmed ID: 17925433 Different Composition of the Human and the Mouse Gammadelta T Cell Receptor Explains Different Phenotypes of CD3gamma and CD3delta Immunodeficiencies The Journal of Experimental Medicine. Oct, 2007 | Pubmed ID: 17923503 A Native Antibody-based Mobility-shift Technique (NAMOS-assay) to Determine the Stoichiometry of Multiprotein Complexes Journal of Immunological Methods. Jul, 2007 | Pubmed ID: 17568608 High-sensitivity Detection and Quantitative Analysis of Native Protein-protein Interactions and Multiprotein Complexes by Flow Cytometry Science's STKE : Signal Transduction Knowledge Environment. Jun, 2007 | Pubmed ID: 17551170 Full Activation of the T Cell Receptor Requires Both Clustering and Conformational Changes at CD3 Immunity. Jan, 2007 | Pubmed ID: 17188005 Overlapping Functions of Human CD3delta and Mouse CD3gamma in Alphabeta T-cell Development Revealed in a Humanized CD3gamma-mouse Blood. Nov, 2006 | Pubmed ID: 16888097 Identification of Disulfide Bonds in the Ig-alpha/Ig-beta Component of the B Cell Antigen Receptor Using the Drosophila S2 Cell Reconstitution System International Immunology. Sep, 2006 | Pubmed ID: 16877534 Blue Native Polyacrylamide Gel Electrophoresis (BN-PAGE) for the Identification and Analysis of Multiprotein Complexes Science's STKE : Signal Transduction Knowledge Environment. Jul, 2006 | Pubmed ID: 16868305 T-cell Antigen-receptor Stoichiometry: Pre-clustering for Sensitivity EMBO Reports. May, 2006 | Pubmed ID: 16670682 A Conformation- and Avidity-based Proofreading Mechanism for the TCR-CD3 Complex Trends in Immunology. Apr, 2006 | Pubmed ID: 16527543 Two Dimensional Blue Native-/SDS-PAGE Analysis of SLP Family Adaptor Protein Complexes Immunology Letters. Apr, 2006 | Pubmed ID: 16356554 Differences in Pairing and Cluster Formation of T Cell Receptor Alpha- and Beta-chains in T Cell Clones and Fusion Hybridomas Immunobiology. 2005 | Pubmed ID: 16323705 Subproteomic Analysis of Metal-interacting Proteins in Human B Cells Proteomics. Sep, 2005 | Pubmed ID: 16097032 Coexistence of Multivalent and Monovalent TCRs Explains High Sensitivity and Wide Range of Response The Journal of Experimental Medicine. Aug, 2005 | Pubmed ID: 16087711 Adenosine and CAMP Are Potent Inhibitors of the NF-kappa B Pathway Downstream of Immunoreceptors European Journal of Immunology. Jan, 2005 | Pubmed ID: 15580656 Biochemical Differences in the Alphabeta T Cell Receptor.CD3 Surface Complex Between CD8+ and CD4+ Human Mature T Lymphocytes The Journal of Biological Chemistry. Jun, 2004 | Pubmed ID: 15060077 Two-dimensional Blue Native/SDS Gel Electrophoresis of Multi-protein Complexes from Whole Cellular Lysates: a Proteomics Approach Molecular & Cellular Proteomics : MCP. Feb, 2004 | Pubmed ID: 14665681 A High-molecular-weight Complex of Membrane Proteins BAP29/BAP31 is Involved in the Retention of Membrane-bound IgD in the Endoplasmic Reticulum Proceedings of the National Academy of Sciences of the United States of America. Aug, 2003 | Pubmed ID: 12886015 Initiation of TCR Signaling: Regulation Within CD3 Dimers Immunological Reviews. Feb, 2003 | Pubmed ID: 12614350 Amplification of B Cell Antigen Receptor Signaling by a Syk/ITAM Positive Feedback Loop Molecular Cell. Nov, 2002 | Pubmed ID: 12453414 Recruitment of Nck by CD3 Epsilon Reveals a Ligand-induced Conformational Change Essential for T Cell Receptor Signaling and Synapse Formation Cell. Jun, 2002 | Pubmed ID: 12110186 Blauwe Inheemse polyacrylamidegelelektroforese (BN-PAGE) voor de Analyse van multiprotein complexen van Cellular Lysaten Gina J. Fiala1,2,3, Wolfgang W. A. Schamel*2,3, Britta Blumenthal*3 1Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, 2Centre for Biological Signalling Studies (bioss) and Biology III, Faculty of Biology, University of Freiburg, 3Department of Molecular Immunology, Max-Planck-Institute of Immunology and Epigenetics JoVE 2164 Biologia
Blauwe Inheemse polyacrylamidegelelektroforese (BN-PAGE) voor de Analyse van multiprotein complexen van Cellular Lysaten Gina J. Fiala1,2,3, Wolfgang W. A. Schamel*2,3, Britta Blumenthal*3 1Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, 2Centre for Biological Signalling Studies (bioss) and Biology III, Faculty of Biology, University of Freiburg, 3Department of Molecular Immunology, Max-Planck-Institute of Immunology and Epigenetics JoVE 2164 Biologia