Xi Lei Department of Pharmacology University of Saskatchewan Biography Publications Institution JoVE Articles Xi Lei has not added a biography. If you are Xi Lei and would like to personalize this page please email our Author Liaison for assistance. Publications Chronic Treatment with Long Acting Phosphodiesterase-5 Inhibitor Tadalafil Alters Proteomic Changes Associated with Cytoskeletal Rearrangement and Redox Regulation in Type 2 Diabetic Hearts Basic Research in Cardiology. Mar, 2012 | Pubmed ID: 22311732 Quantitative Assessment of the Effect of MTHFR Polymorphisms on the Risk of Lung Carcinoma Molecular Biology Reports. Jan, 2012 | Pubmed ID: 22215214 CXCL12 G801A Polymorphism and Breast Cancer Risk: a Meta-analysis Molecular Biology Reports. Feb, 2012 | Pubmed ID: 21643956 Emerging New Uses of Phosphodiesterase-5 Inhibitors in Cardiovascular Diseases Experimental and Clinical Cardiology. 2011 | Pubmed ID: 22131856 Dysregulated Atrial Gene Expression of Osteoprotegerin/receptor Activator of Nuclear Factor-κB (RANK)/RANK Ligand Axis in the Development and Progression of Atrial Fibrillation Circulation Journal : Official Journal of the Japanese Circulation Society. 2011 | Pubmed ID: 22001292 Integrated Diffuse Optical Tomography and Photoacoustic Tomography: Phantom Validations Biomedical Optics Express. Aug, 2011 | Pubmed ID: 21833371 Type 2 Diabetic Obese Db/db Mice Are Refractory to Myocardial Ischemic Postconditioning In Vivo: Potential Role for Hsp20, F(1) -ATPase δ, and Echs1 Journal of Cellular and Molecular Medicine. Jul, 2011 | Pubmed ID: 21722304 Dietary Nitrate Supplementation Protects Against Doxorubicin-induced Cardiomyopathy by Improving Mitochondrial Function Journal of the American College of Cardiology. May, 2011 | Pubmed ID: 21596234 Early Changes in Morphology and Intraocular Pressure by Size of Clear Corneal Incision Cornea. Jun, 2011 | Pubmed ID: 21282997 Identification of Protein Targets Underlying Dietary Nitrate-induced Protection Against Doxorubicin Cardiotoxicity Journal of Cellular and Molecular Medicine. Nov, 2011 | Pubmed ID: 21251210 A Rapid and Simple Chemiluminescence Method for Screening Levels of Inosine and Hypoxanthine in Non-traumatic Chest Pain Patients Luminescence : the Journal of Biological and Chemical Luminescence. Jan-Feb, 2011 | Pubmed ID: 20017127 Photoacoustic Imaging Based on MEMS Mirror Scanning Biomedical Optics Express. 2010 | Pubmed ID: 21258548 Hypoxia Inducible Factor 1 (HIF-1) and Cardioprotection Acta Pharmacologica Sinica. Sep, 2010 | Pubmed ID: 20711226 Long-acting Phosphodiesterase-5 Inhibitor Tadalafil Attenuates Doxorubicin-induced Cardiomyopathy Without Interfering with Chemotherapeutic Effect The Journal of Pharmacology and Experimental Therapeutics. Sep, 2010 | Pubmed ID: 20543097 The Protective Effects of Ambroxol on Radiation Lung Injury and Influence on Production of Transforming Growth Factor Beta1 and Tumor Necrosis Factor Alpha Medical Oncology (Northwood, London, England). Sep, 2010 | Pubmed ID: 19636975 Design of One-to-one Recognition Triple Au Nanoparticles DNA Probe and Its Application in the Electrochemical DNA Biosensor Chemical Communications (Cambridge, England). Dec, 2009 | Pubmed ID: 19904360 Investigation on Solvation and Protonation of Meso-tetrakis(p-sulfonatophenyl)porphyrin in Imidazolium-based Ionic Liquids by Spectroscopic Methods Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy. Oct, 2009 | Pubmed ID: 19648056 Investigation of Voltammetric Enzyme-linked Immunoassay System Based on N-heterocyclic Substrate of 2,3-diaminopyridine Talanta. Jun, 2009 | Pubmed ID: 19362207 ERK Phosphorylation Mediates Sildenafil-induced Myocardial Protection Against Ischemia-reperfusion Injury in Mice American Journal of Physiology. Heart and Circulatory Physiology. May, 2009 | Pubmed ID: 19286961 Pivotal Effects of Phosphodiesterase Inhibitors on Myocyte Contractility and Viability in Normal and Ischemic Hearts Acta Pharmacologica Sinica. Jan, 2009 | Pubmed ID: 19060915 Commentaries on Viewpoint: Effect of Altitude on Leptin, Does It Go Up or Down? Journal of Applied Physiology (Bethesda, Md. : 1985). Nov, 2008 | Pubmed ID: 19031619 Loss of Myocardial Ischemic Postconditioning in Adenosine A1 and Bradykinin B2 Receptors Gene Knockout Mice Circulation. Sep, 2008 | Pubmed ID: 18824766 The Current Strategy of Repair of Tetralogy of Fallot in Children and Adults Cardiology in the Young. Dec, 2008 | Pubmed ID: 18812012 Protein Kinase G-dependent Cardioprotective Mechanism of Phosphodiesterase-5 Inhibition Involves Phosphorylation of ERK and GSK3beta The Journal of Biological Chemistry. Oct, 2008 | Pubmed ID: 18723505 Essential Role of Mitochondrial Ca2+-activated and ATP-sensitive K+ Channels in Sildenafil-induced Late Cardioprotection Journal of Molecular and Cellular Cardiology. Jan, 2008 | Pubmed ID: 18021798 Effects of Salicylic Acid on Post-ischaemic Ventricular Function and Purine Efflux in Isolated Mouse Hearts Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. Nov-Dec, 2007 | Pubmed ID: 17852081 ENOS Phosphorylation: a Pivotal Molecular Switch in Vasodilation and Cardioprotection? Journal of Molecular and Cellular Cardiology. Feb, 2007 | Pubmed ID: 17174975 Rapamycin Confers Preconditioning-like Protection Against Ischemia-reperfusion Injury in Isolated Mouse Heart and Cardiomyocytes Journal of Molecular and Cellular Cardiology. Aug, 2006 | Pubmed ID: 16769083 [Dynamic Changes of Morphological Parameters of Tobacco Root in Field] Ying Yong Sheng Tai Xue Bao = The Journal of Applied Ecology / Zhongguo Sheng Tai Xue Xue Hui, Zhongguo Ke Xue Yuan Shenyang Ying Yong Sheng Tai Yan Jiu Suo Zhu Ban. Mar, 2006 | Pubmed ID: 16724726 Hypercholesterolemia Enhances Tolerance to Lethal Systemic Hypoxia in Middle-aged Mice: Possible Role of VEGF Downregulation in Brain Molecular and Cellular Biochemistry. Oct, 2006 | Pubmed ID: 16718361 Genetic Deletion of Fas Receptors or Fas Ligands Does Not Reduce Infarct Size After Acute Global Ischemia-reperfusion in Isolated Mouse Heart Cell Biochemistry and Biophysics. 2006 | Pubmed ID: 16456239 Silencing Heat Shock Factor 1 by Small Interfering RNA Abrogates Heat Shock-induced Cardioprotection Against Ischemia-reperfusion Injury in Mice Journal of Molecular and Cellular Cardiology. Oct, 2005 | Pubmed ID: 16125197 Pharmacological Preconditioning with Sildenafil: Basic Mechanisms and Clinical Implications Vascular Pharmacology. Apr-May, 2005 | Pubmed ID: 15922255 Phosphodiesterase-5 Inhibitor Sildenafil Preconditions Adult Cardiac Myocytes Against Necrosis and Apoptosis. Essential Role of Nitric Oxide Signaling The Journal of Biological Chemistry. Apr, 2005 | Pubmed ID: 15668244 Cobalt Chloride Induces Delayed Cardiac Preconditioning in Mice Through Selective Activation of HIF-1alpha and AP-1 and INOS Signaling American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2004 | Pubmed ID: 15284066 Opening of Ca2+-activated K+ Channels Triggers Early and Delayed Preconditioning Against I/R Injury Independent of NOS in Mice American Journal of Physiology. Heart and Circulatory Physiology. Nov, 2004 | Pubmed ID: 15217801 Cardioprotection with Phosphodiesterase-5 Inhibition--a Novel Preconditioning Strategy Journal of Molecular and Cellular Cardiology. Feb, 2004 | Pubmed ID: 14871543 Sildenafil-induced Cardioprotection in Rabbits Cardiovascular Research. Dec, 2003 | Pubmed ID: 14659816 Sildenafil Induces Delayed Preconditioning Through Inducible Nitric Oxide Synthase-dependent Pathway in Mouse Heart Circulation Research. Apr, 2003 | Pubmed ID: 12637371 Exercise Does Not Protect the Female Heart: an Unconvincing Conclusion? Circulation Research. Aug, 2002 | Pubmed ID: 12169655 Evidence That NOS2 Acts As a Trigger and Mediator of Late Preconditioning Induced by Acute Systemic Hypoxia American Journal of Physiology. Heart and Circulatory Physiology. Jul, 2002 | Pubmed ID: 12063268 Tracking Neutrophil Intraluminal Crawling, Transendothelial Migration and Chemotaxis in Tissue by Intravital Video Microscopy Najia Xu1, Xi Lei1, Lixin Liu1 1Department of Pharmacology, University of Saskatchewan JoVE 3296 Imunologia e Infecção
Tracking Neutrophil Intraluminal Crawling, Transendothelial Migration and Chemotaxis in Tissue by Intravital Video Microscopy Najia Xu1, Xi Lei1, Lixin Liu1 1Department of Pharmacology, University of Saskatchewan JoVE 3296 Imunologia e Infecção