Yasuko Orba Division of Molecular Pathobiology, Research Center for Zoonosis Control Hokkaido University Biography Publications Institution JoVE Articles Yasuko Orba has not added a biography. If you are Yasuko Orba and would like to personalize this page please email our Author Liaison for assistance. Publications "Integrated Diagnosis" of Pilocytic Astrocytoma: Molecular Diagnostic Procedure for an Unusual Case Pathology International. Dec, 2018 | Pubmed ID: 30417961 Fatal Tickborne Phlebovirus Infection in Captive Cheetahs, Japan Emerging Infectious Diseases. 09, 2018 | Pubmed ID: 30124411 Single Amino Acid Mutation in Dengue Virus NS4B Protein Has Opposing Effects on Viral Proliferation in Mammalian and Mosquito Cells Japanese Journal of Infectious Diseases. 11, 2018 | Pubmed ID: 30068888 Identification of Group A Rotaviruses from Zambian Fruit Bats Provides Evidence for Long-distance Dispersal Events in Africa Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. 09, 2018 | Pubmed ID: 29792990 Identification of Compound-B, a Novel Anti-dengue Virus Agent Targeting the Non-structural Protein 4A Antiviral Research. Jul, 2018 | Pubmed ID: 29758236 Discovery of Mwinilunga Alphavirus: A Novel Alphavirus in Culex Mosquitoes in Zambia Virus Research. 05, 2018 | Pubmed ID: 29630910 Ribavirin-related Compounds Exert in Vitro Inhibitory Effects Toward Rabies Virus Antiviral Research. Jun, 2018 | Pubmed ID: 29601893 The Role of Heparan Sulfate Proteoglycans As an Attachment Factor for Rabies Virus Entry and Infection The Journal of Infectious Diseases. May, 2018 | Pubmed ID: 29529215 Detection of Novel Gammaherpesviruses from Fruit Bats in Indonesia Journal of Medical Microbiology. Mar, 2018 | Pubmed ID: 29458559 Development of a Rapid and Quantitative Method for the Analysis of Viral Entry and Release Using a NanoLuc Luciferase Complementation Assay Virus Research. 01, 2018 | Pubmed ID: 29074234 [Discovery of DNA Viruses in Wildlife in Zambia and Indonesia] Uirusu. 2017 | Pubmed ID: 30369539 Identification of the Same Polyomavirus Species in Different African Horseshoe Bat Species is Indicative of Short-range Host-switching Events The Journal of General Virology. 11, 2017 | Pubmed ID: 28984241 Discovery of Novel Cyclic Peptide Inhibitors of Dengue Virus NS2B-NS3 Protease with Antiviral Activity Bioorganic & Medicinal Chemistry Letters. 08, 2017 | Pubmed ID: 28539222 Discovery of African Bat Polyomaviruses and Infrequent Recombination in the Large T Antigen in the Polyomaviridae The Journal of General Virology. Apr, 2017 | Pubmed ID: 28430100 Discovery of a Novel Antiviral Agent Targeting the Nonstructural Protein 4 (nsP4) of Chikungunya Virus Virology. 05, 2017 | Pubmed ID: 28236746 Animal Models of Emerging Tick-Borne Phleboviruses: Determining Target Cells in a Lethal Model of SFTSV Infection Frontiers in Microbiology. 2017 | Pubmed ID: 28194148 Valosin-containing Protein (VCP/p97) Plays a Role in the Replication of West Nile Virus Virus Research. 01, 2017 | Pubmed ID: 27914931 Isolation of a Simian Immunodeficiency Virus from a Malbrouck (Chlorocebus Cynosuros) Archives of Virology. Feb, 2017 | Pubmed ID: 27804019 Multi-reassortant G3P[3] Group A Rotavirus in a Horseshoe Bat in Zambia The Journal of General Virology. 10, 2016 | Pubmed ID: 27574104 Divergent Bufavirus Harboured in Megabats Represents a New Lineage of Parvoviruses Scientific Reports. 04, 2016 | Pubmed ID: 27113297 Generation of Recombinant Rabies Viruses Encoding NanoLuc Luciferase for Antiviral Activity Assays Virus Research. Apr, 2016 | Pubmed ID: 26869397 Rab8b Regulates Transport of West Nile Virus Particles from Recycling Endosomes The Journal of Biological Chemistry. Mar, 2016 | Pubmed ID: 26817838 Distinct Lineages of Bufavirus in Wild Shrews and Nonhuman Primates Emerging Infectious Diseases. Jul, 2015 | Pubmed ID: 26079728 Detection of Novel Polyomaviruses in Fruit Bats in Indonesia Archives of Virology. Apr, 2015 | Pubmed ID: 25670407 Detection of Coronavirus Genomes in Moluccan Naked-backed Fruit Bats in Indonesia Archives of Virology. Apr, 2015 | Pubmed ID: 25643817 Metagenomic Analysis of the Shrew Enteric Virome Reveals Novel Viruses Related to Human Stool-associated Viruses The Journal of General Virology. Feb, 2015 | Pubmed ID: 25381053 Orthopoxvirus Infection Among Wildlife in Zambia The Journal of General Virology. Feb, 2015 | Pubmed ID: 25319753 [Epidemiological and Basic Research Activity Targeting Polyomaviruses] Uirusu. 2014 | Pubmed ID: 25765977 A Nairovirus Isolated from African Bats Causes Haemorrhagic Gastroenteritis and Severe Hepatic Disease in Mice Nature Communications. Dec, 2014 | Pubmed ID: 25451856 Detection and Characterization of Zoonotic Pathogens of Free-ranging Non-human Primates from Zambia Parasites & Vectors. Oct, 2014 | Pubmed ID: 25358853 Autophagy Inhibits Viral Genome Replication and Gene Expression Stages in West Nile Virus Infection Virus Research. Oct, 2014 | Pubmed ID: 25091564 Role of the C-terminal Region of Vervet Monkey Polyomavirus 1 VP1 in Virion Formation The Journal of Veterinary Medical Science. May, 2014 | Pubmed ID: 24419975 Molecular Epidemiology of Paramyxoviruses in Frugivorous Eidolon Helvum Bats in Zambia The Journal of Veterinary Medical Science. Apr, 2014 | Pubmed ID: 24389743 Molecular Epidemiology of Paramyxoviruses in Zambian Wild Rodents and Shrews The Journal of General Virology. Feb, 2014 | Pubmed ID: 24189618 Viroporin Activity of the JC Polyomavirus is Regulated by Interactions with the Adaptor Protein Complex 3 Proceedings of the National Academy of Sciences of the United States of America. Nov, 2013 | Pubmed ID: 24167297 Cysteine Residues in the Major Capsid Protein, Vp1, of the JC Virus Are Important for Protein Stability and Oligomer Formation PloS One. 2013 | Pubmed ID: 24130786 Human Parainfluenza Virus Type 3 in Wild Nonhuman Primates, Zambia Emerging Infectious Diseases. 2013 | Pubmed ID: 23968816 Characterization of Japanese Encephalitis Virus Infection in an Immortalized Mesencephalic Cell Line, CSM14.1 Microbiology and Immunology. Oct, 2013 | Pubmed ID: 23905906 Gold Nanoparticles As a Vaccine Platform: Influence of Size and Shape on Immunological Responses in Vitro and in Vivo ACS Nano. May, 2013 | Pubmed ID: 23631767 Relationship Between Methyl CpG Binding Protein 2 and JC Viral Proteins Japanese Journal of Infectious Diseases. 2013 | Pubmed ID: 23514909 Identification of a Novel Polyomavirus from Vervet Monkeys in Zambia The Journal of General Virology. Jun, 2013 | Pubmed ID: 23426354 Cross-reactivity of Secondary Antibodies Against African Rodents and Application for Sero-surveillance The Journal of Veterinary Medical Science. 2013 | Pubmed ID: 23386359 Role of JC Virus Agnoprotein in Virion Formation Microbiology and Immunology. Sep, 2012 | Pubmed ID: 22708997 The Sphingosine-1-phosphate Transporter Spns2 Expressed on Endothelial Cells Regulates Lymphocyte Trafficking in Mice The Journal of Clinical Investigation. Apr, 2012 | Pubmed ID: 22406534 Accumulation of Ubiquitinated Proteins is Related to West Nile Virus-induced Neuronal Apoptosis Neuropathology : Official Journal of the Japanese Society of Neuropathology. Aug, 2012 | Pubmed ID: 22129084 Detection and Characterization of a Novel Polyomavirus in Wild Rodents The Journal of General Virology. Apr, 2011 | Pubmed ID: 21177925 Natalizumab Has No Direct Biological Effect on JC Virus Infectivity in Permissive Human Neural Cell Lines Journal of Medical Virology. Jul, 2010 | Pubmed ID: 20513089 The Human Polyoma JC Virus Agnoprotein Acts As a Viroporin PLoS Pathogens. Mar, 2010 | Pubmed ID: 20300659 Large T Antigen Promotes JC Virus Replication in G2-arrested Cells by Inducing ATM- and ATR-mediated G2 Checkpoint Signaling The Journal of Biological Chemistry. Jan, 2010 | Pubmed ID: 19903823 Inhibition of the SDF-1alpha-CXCR4 Axis by the CXCR4 Antagonist AMD3100 Suppresses the Migration of Cultured Cells from ATL Patients and Murine Lymphoblastoid Cells from HTLV-I Tax Transgenic Mice Blood. Oct, 2009 | Pubmed ID: 19657116 An SiRNA Against JC Virus (JCV) Agnoprotein Inhibits JCV Infection in JCV-producing Cells Inoculated in Nude Mice Neuropathology : Official Journal of the Japanese Society of Neuropathology. Jun, 2008 | Pubmed ID: 18179406 Pharmacological Cdk Inhibitor R-Roscovitine Suppresses JC Virus Proliferation Virology. Jan, 2008 | Pubmed ID: 17919676 [Recent Research on the JC Virus] Brain and Nerve = Shinkei Kenkyu No Shinpo. Feb, 2007 | Pubmed ID: 17380774 DDX1 Promotes Proliferation of the JC Virus Through Transactivation of Its Promoter Microbiology and Immunology. 2007 | Pubmed ID: 17380054 Identification of DDX1 As a JC Virus Transcriptional Control Region-binding Protein Microbiology and Immunology. 2007 | Pubmed ID: 17380053 [Recent Research on the JC Virus] No to Shinkei = Brain and Nerve. Feb, 2007 | Pubmed ID: 17315751 A Ubiquitin Ligase HRD1 Promotes the Degradation of Pael Receptor, a Substrate of Parkin Journal of Neurochemistry. Dec, 2006 | Pubmed ID: 17059562 Characterization and Application of Polyclonal Antibodies That Specifically Recognize JC Virus Large T Antigen Acta Neuropathologica. Apr, 2006 | Pubmed ID: 16479389 Dissociation of Heterochromatin Protein 1 from Lamin B Receptor Induced by Human Polyomavirus Agnoprotein: Role in Nuclear Egress of Viral Particles EMBO Reports. May, 2005 | Pubmed ID: 15864296 Establishment of an Immunoscreening System Using Recombinant VP1 Protein for the Isolation of a Monoclonal Antibody That Blocks JC Virus Infection Biochemical and Biophysical Research Communications. Feb, 2005 | Pubmed ID: 15629455 Triglyceride Accumulation and Altered Composition of Triglyceride-associated Fatty Acids in the Skin of Tenascin-X-deficient Mice Genes to Cells : Devoted to Molecular & Cellular Mechanisms. Aug, 2004 | Pubmed ID: 15298681 Induction of Matrix Metalloproteinase-2 by Tenascin-X Deficiency is Mediated Through the C-Jun N-terminal Kinase and Protein Tyrosine Kinase Phosphorylation Pathway Experimental Cell Research. Jul, 2004 | Pubmed ID: 15212943 Inhibition of Virus Production in JC Virus-infected Cells by Postinfection RNA Interference Journal of Virology. Jul, 2004 | Pubmed ID: 15194803 Application of Laser Capture Microdissection to Cytologic Specimens for the Detection of Immunoglobulin Heavy Chain Gene Rearrangement in Patients with Malignant Lymphoma Cancer. Aug, 2003 | Pubmed ID: 12925980 [JC Virus Infection (progressive Multifocal Leukoencephalopathy)] Nihon Rinsho. Japanese Journal of Clinical Medicine. Feb, 2003 | Pubmed ID: 12722200 JC Virus Agnoprotein Colocalizes with Tubulin Journal of Neurovirology. 2003 | Pubmed ID: 12709865 Clinicopathological Studies of Peripheral Neuropathy in Churg-Strauss Syndrome Neuropathology : Official Journal of the Japanese Society of Neuropathology. Dec, 2002 | Pubmed ID: 12564771 Distribution of Extracellular Matrix Tenascin-X in Sciatic Nerves Acta Neuropathologica. Nov, 2002 | Pubmed ID: 12410392 Expression of JC Virus Agnoprotein in Progressive Multifocal Leukoencephalopathy Brain Acta Neuropathologica. Aug, 2002 | Pubmed ID: 12111355 [Molecular Neuropathology of JC Virus] No to Shinkei = Brain and Nerve. Feb, 2002 | Pubmed ID: 11889755 Immunohistochemical Detection of Hepatocellular Carcinoma in the Setting of Ongoing Necrosis After Radiofrequency Ablation Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Feb, 2002 | Pubmed ID: 11850539 Identification des souris et des répertoires d’anticorps humain par séquençage de prochaine génération Lin Sun1, Naoko Kono2, Hiroyuki Toh3, Hanbing Xue1, Kaori Sano4,5, Tadaki Suzuki4, Akira Ainai4, Yasuko Orba6, Junya Yamagishi7,8, Hideki Hasegawa4,5, Yoshimasa Takahashi9, Shigeyuki Itamura2, Kazuo Ohnishi9,10 1Graduate School of Life and Environmental Sciences, University of Tsukuba, 2Center for Influenza Virus Research, National Institute of Infectious Diseases, 3School of Science and Technology, Kwansei Gakuin University, 4Department of Pathology, National Institute of Infectious Diseases, 5Division of Infectious Diseases Pathology, Department of Global Infectious Diseases, Tohoku University Graduate School of Medicine, 6Division of Molecular Pathobiology, Research Center for Zoonosis Control, Hokkaido University, 7Division of Collaboration and Education, Research Center for Zoonosis Control, Hokkaido University, 8Global Station for Zoonosis Control, GI-CoRE, Hokkaido University, 9Department of Immunology, National Institute of Infectious Diseases, 10Faculty of Life and Environmental Sciences, University of Tsukuba JoVE 58804 Imunologia e Infecção
Identification des souris et des répertoires d’anticorps humain par séquençage de prochaine génération Lin Sun1, Naoko Kono2, Hiroyuki Toh3, Hanbing Xue1, Kaori Sano4,5, Tadaki Suzuki4, Akira Ainai4, Yasuko Orba6, Junya Yamagishi7,8, Hideki Hasegawa4,5, Yoshimasa Takahashi9, Shigeyuki Itamura2, Kazuo Ohnishi9,10 1Graduate School of Life and Environmental Sciences, University of Tsukuba, 2Center for Influenza Virus Research, National Institute of Infectious Diseases, 3School of Science and Technology, Kwansei Gakuin University, 4Department of Pathology, National Institute of Infectious Diseases, 5Division of Infectious Diseases Pathology, Department of Global Infectious Diseases, Tohoku University Graduate School of Medicine, 6Division of Molecular Pathobiology, Research Center for Zoonosis Control, Hokkaido University, 7Division of Collaboration and Education, Research Center for Zoonosis Control, Hokkaido University, 8Global Station for Zoonosis Control, GI-CoRE, Hokkaido University, 9Department of Immunology, National Institute of Infectious Diseases, 10Faculty of Life and Environmental Sciences, University of Tsukuba JoVE 58804 Imunologia e Infecção