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Journal / Neuroscience / Novel Apparatus and Method for Drug Reinforcement
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JoVE Journal Neuroscience
Novel Apparatus and Method for Drug Reinforcement
 

Novel Apparatus and Method for Drug Reinforcement

Article DOI: 10.3791/1998-v • 07:33 min • August 20th, 2010
August 20th, 2010 •
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1College of Pharmacy, Division of Pharmacology and Toxicology, University of Texas at Austin

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Operant drug self-administration and conditioned place preference (CPP) procedures are expansively used in research to model various components of drug reinforcement, consumption, and addiction in humans. In this report, we combined traditional CPP and self-administration methods as a novel approach to studying drug reinforcement and addiction in rats.

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Novel Apparatus Method Drug Reinforcement Animal Models Neurobiological Mechanisms Drug Addiction Operant Drug Self-administration Conditioned Place Preference CPP Procedures Animal Research Drug Reinforcement In Rats Med Associate Operant Chambers Sensory Stimuli Plexiglas-constructed Neutral Zone Motivational Aspects Of Drug Intake Self-administration Drug-free Assessment Drug/cue Conditioning Strength Cocaine Self-administration Saline Self-infusion CPP Test
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