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Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis
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Imunologia e Infecção
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JoVE Journal Imunologia e Infecção
Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis

Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis

DOI:
10.3791/2181-v

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10:52 min

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December 17, 2010

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, , ,
1Department of Pathology,The Johns Hopkins University

Capítulos

  • 00:05Título
  • 01:00Introduction
  • 03:21Collection and Storage of Mouse Pituitary Glands
  • 04:40Extraction of Mouse Pituitary Proteins
  • 07:00Preparation of the Emulsion
  • 09:34Conclusion

Summary

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Autoimmune hypophysitis can be reproduced in mice by injecting an extract of mouse pituitary proteins.

Tags

Mouse Pituitary ImmunogenExperimental Autoimmune HypophysitisChronic InflammationPituitary GlandAutoimmunityRare DiseaseCancer PatientsInhibitory ReceptorsT LymphocytesCTLA-4PD-1 ReceptorsAdjuvantProtein ExtractionSJL Mice

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