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A Procedure for Studying the Footshock-Induced Reinstatement of Cocaine Seeking in Laboratory Rats
 

A Procedure for Studying the Footshock-Induced Reinstatement of Cocaine Seeking in Laboratory Rats

Article DOI: 10.3791/2265-v • 08:55 min • January 6th, 2011
January 6th, 2011 •
1, 1, 1
1Psychology, University of Toronto Scarborough

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Animal models of relapse, known as reinstatement procedures, have been used extensively to study the role of stress in relapse to drug seeking. Here, we report on a method for inducing the reinstatement of cocaine seeking in laboratory rats via acute exposures to mild, intermittent electric footshock.

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Footshock-induced Reinstatement Cocaine Seeking Laboratory Rats Drug Addiction Relapse Animal Models Neurobiology Phenomenology Reinstatement Procedures Drug Self-administration Model Operant Response Extinction Drug Seeking Training Drug Drug-associated Cues Stressor Acute Non-contingent Exposure Environmental Stimuli Stress Mild Intermittent Electric Footshocks
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