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Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging
 

Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging

Article DOI: 10.3791/2844-v • 13:22 min • July 21st, 2011
July 21st, 2011 •
*1, *1, *1, *1, 1
1Department of Chemistry, Wayne State University
* These authors contributed equally

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We demonstrate the metalation, purification, and characterization of lanthanide complexes. The complexes described here can be conjugated to macromolecules to enable tracking of these molecules using magnetic resonance imaging.

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Preparation Purification Characterization Lanthanide Complexes Contrast Agents Magnetic Resonance Imaging Polyaminopolycarboxylate-based Ligands Chelate Functional Groups Conjugation Amine-reactive Activated Esters Isothiocyanate Groups Thiol-reactive Maleimides Metalation Procedures Metal Starting Materials Purification Methods Biomedical Scientists
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