JoVE Journal
Biology
Biology
This Conteúdo is Open Access.
Capítulos
Resumo
Please note that all translations are automatically generated.
The HO-stimulated translocation assay monitors single-strand annealing following the creation of DNA double-strand breaks at multiple loci in diploid Saccharomyces cerevisiae. This mechanism may model genome rearrangements in somatic cells of higher eukaryotes following exposure to high doses of ionizing radiation.