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Isolation and Chemical Characterization of Lipid A fra Gram-negative bakterier
 
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Isolation and Chemical Characterization of Lipid A fra Gram-negative bakterier

Article DOI: 10.3791/50623-v • 12:57 min • September 16th, 2013
September 16th, 2013 •
1, 2, 2, 1,3
1Section of Molecular Genetics and Microbiology, The University of Texas at Austin, 2Department of Chemistry and Biochemistry, The University of Texas at Austin, 3The Institute of Cellular and Molecular Biology, The University of Texas at Austin

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Isolering og karakterisering av lipid Et domene av lipopolysakkarid (LPS) fra gramnegative bakterier gir innsikt i celleoverflatebaserte mekanismer for antibiotikaresistens, bakteriell overlevelse og fitness, og hvordan kjemisk mangfoldig lipid A molekylære arter differentially modulere vert medfødte immunresponser.

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Chemistry membranlipider Toll-lignende reseptorer endotoksiner glykolipider lipopolysakkarider Lipid A Microbiology Lipids lipid A Bligh-Dyer tynnsjiktskromatografi (TLC) lipopolysakkarid massespektrometri Collision Induced Dissosiasjon (CID ) Photodissociation (PD)
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