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Journal / Chemistry / Polymalic Acid-based Nano Biopolymers for…
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Chemistry

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JoVE Journal Chemistry
Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers
 

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

Article DOI: 10.3791/50668-v • 14:20 min • June 13th, 2014
June 13th, 2014 •
1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1
1Nanomedicine Research Center, Department of Neurosurgery, Cedars-Sinai Medical Center

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An example of a nano drug based on polymalic acid is presented towards the rational design of personalized medicine that is applicable to cancer. It describes the synthesis of a nano drug to treat Her2-positive human breast cancer in a nude mouse.

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Keywords: Polymalic Acid Nano Biopolymers Tumor Markers Personalized Medicine Her2-positive Breast Cancer Antisense Oligonucleotides Tumor Targeting Biodegradable Non-toxic Non-immunogenic Mouse Model
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