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A New Murine Model of Endovascular Aortic Aneurysm Repair
 

A New Murine Model of Endovascular Aortic Aneurysm Repair

Article DOI: 10.3791/50740-v • 08:52 min • July 7th, 2013
July 7th, 2013 •
1, 1, 1, 1, 1,2, 3, 4, 4, 1, 1,5
1INSERM U698 Cardiovascular Remodelling, Hôpital X. Bichat, AP-HP, Paris, 2Bio-Ingénierie des Polymères Cardiovasculaires (BPC), Institut Galilée - Université Paris 13, Paris, France, 3Service de Chirurgie Vasculaire, Hôpital Henri Mondor, AP-HP, Université Paris-Est Creteil, 4Ecole de chirurgie de l'assistance publique des hôpitaux de Paris, 5Service de Chirurgie Cardiaque et Vasculaire, Hôpital Européen Georges Pompidou, AP-HP, Université René Descartes

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Histological and biochemical modifications after aneurysm endograft exclusion are still unclear. We describe a new model of endograft implantation on a murine aneurysm. Through thrombus analysis with and without persistant circulating blood stream interface, and new endovascular biomaterials evaluation, this model will help to better understand endovascular aneurysm exclusion pathobiology.

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Keyword Extraction: Endovascular Aortic Aneurysm Repair Abdominal Aortic Aneurysm Elastase-induced AAA Model Endovascular Exclusion Covered Coronary Stent Graft Angiography Aspirin Neutrophils Endothelium Platelets
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