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Ultrasound Imaging-guided Intracardiac Injection to Develop a Mouse Model of Breast Cancer Brain Metastases Followed by Longitudinal MRI
 

Ultrasound Imaging-guided Intracardiac Injection to Develop a Mouse Model of Breast Cancer Brain Metastases Followed by Longitudinal MRI

Article DOI: 10.3791/51146-v • 08:36 min • March 6th, 2014
March 6th, 2014 •
1, 1
1Radiology, University of Texas Southwestern Medical Center

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A breast cancer brain metastasis mouse model is established with ultrasound imaging-guided intracardiac injection of MDA-MB231/Br-GFP cells. Development of multifocal intracranial metastases has been monitored longitudinally using high-resolution 9.4 T MRI.

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Keywords: Ultrasound Imaging Intracardiac Injection Mouse Model Breast Cancer Brain Metastases MRI Longitudinal Imaging Athymic Nude Mice Breast Cancer Cells Metastatic Spread In Vivo Imaging T2-weighted MRI Tumor Growth
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