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Journal / Neuroscience / An In Vitro Adult Mouse Muscle-nerve Preparation…
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Neuroscience

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JoVE Journal Neuroscience
An In Vitro Adult Mouse Muscle-nerve Preparation for Studying the Firing Properties of Muscle Afferents
 

An In Vitro Adult Mouse Muscle-nerve Preparation for Studying the Firing Properties of Muscle Afferents

Article DOI: 10.3791/51948-v • 10:36 min • September 24th, 2014
September 24th, 2014 •
1, 2, 3, 4
1Department of Mechanical Engineering, San José State University, 2J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, 3Department of Physiology, Emory University School of Medicine, 4Department of Biological Sciences, San José State University

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Muscle sensory neurons are involved in proprioceptor signaling and also report on metabolic state and injury related events. We describe an adult mouse in vitro muscle-nerve preparation for studies on stretch-activated muscle afferents.

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Keywords: Muscle Afferents Muscle Spindle Golgi Tendon Organ Proprioception Muscle Sensory Neurons Extensor Digitorum Longus In Vitro Preparation Stretch-evoked Response Spike Sorting Muscle Perfusion Genetic Approaches Disease Models
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