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JoVE Journal Developmental Biology
Efficient Derivation of Retinal Pigment Epithelium Cells from Stem Cells
 

Efficient Derivation of Retinal Pigment Epithelium Cells from Stem Cells

Article DOI: 10.3791/52214-v • 07:07 min • March 8th, 2015
March 8th, 2015 •
1,2, 1,2, 2, 1,2
1Department of Cell and Molecular Biology, The Scripps Research Institute, 2Lowy Medical Research Institute

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Resumo
Automatic Translation

Stem cell-derived retinal pigment epithelium (RPE) cells may be used for multiple applications including cell-based therapies for retinal degeneration, disease modeling, and drug studies. Here we present a simple protocol for reproducibly deriving RPE from stem cells.

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Keywords: Retinal Pigment Epithelium RPE Age-related Macular Degeneration AMD Stem Cell Differentiation IPS-RPE Nicotinamide Activin A IDE-1 Cell-based Therapy
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