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JoVE Journal Neuroscience
Non-invasive Assessment of Changes in Corticomotoneuronal Transmission in Humans
 

Non-invasive Assessment of Changes in Corticomotoneuronal Transmission in Humans

Article DOI: 10.3791/52663-v • 09:30 min • May 24th, 2017
May 24th, 2017 •
1, 1,2, 3,4, 3,4
1Department of Medicine, Movement and Sport Science, University of Fribourg (Switzerland), 2Department of Sport Science, University of Freiburg (Germany), 3Department of Neuroscience and Pharmacology, University of Copenhagen, 4Department of Nutrition, Exercise and Sports, University of Copenhagen

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The aim of the present study was to assess changes in transmission at the corticomotoneuronal synapses in humans after repetitive transcranial magnetic stimulation. For this purpose, an electrophysiological method is introduced that allows assessment of pathway specific corticospinal transmission, i.e. differentiation of fast, direct corticospinal pathways from polysynaptic connections.

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Keywords: Corticomotoneuronal Transmission Transcranial Magnetic Stimulation H-reflex Conditioning Neuroplasticity Corticospinal Tract Motor Neuron Corticomotoneuronal Synapse Compound Potentials Surface Electrodes EMG H-reflex M-wave Neuronavigation Figure-eight Coil
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