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A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
 

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

Article DOI: 10.3791/52761-v • 10:26 min • June 2nd, 2015
June 2nd, 2015 •
1, 1, 1, 1, 1, 2, 3, 3, 1, 2, 1
1Department of Radiology, Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, 2Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, 3Daiichi Sankyo Pharma Development

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The goal of this study is to use magnetic resonance venography with long-circulating gadolinium-based contrast agent and direct thrombus imaging for quantitative evaluation of DVT volume in a multicenter, clinical trial setting. Inter- and intra-observer variability assessments were conducted, and reproducibility of the protocol was determined.

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Multicenter MRI Protocol Evaluation Quantification Deep Vein Thrombosis Magnetic Resonance Venography Gadofosveset Total Thrombus Volume Treatment Efficacy Edoxaban Monotherapy Heparin/warfarin Regimen Lower Extremities Direct Thrombus Imaging Reproducibility Analysis Methodology Applicability 3D Magnetic Resonance Venography Quantification Multicenter Trial Setting Edoxaban Thrombus Reduction Imaging Study (eTRIS) Bilateral Quantification 3D-T1W Gradient Echo Sequences Gadofosveset Trisodium Injection Volumetric Measurements Venous Thrombi Total DVT Volume Fresh Thrombus Volume Intra-class Correlation
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