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JoVE Journal
Medicine

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Bioluminescence-Based Tumor Quantification Method for Monitoring Tumor Progression and Treatment Effects in Mouse Lymphoma Models
 

Bioluminescence-Based Tumor Quantification Method for Monitoring Tumor Progression and Treatment Effects in Mouse Lymphoma Models

Article DOI: 10.3791/53609-v 07:12 min July 7th, 2016
July 7th, 2016

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Resumo

Bioluminescence imaging is a well-known tool for localizing tumors and metastases, but quantification of these images often requires complex calculations and particular instruments. We describe the easy-to-use luminoscore method, based on precise acquisition conditions, requiring no calculations, and enabling tumor burden and treatment response to be monitored in mouse models.

Tags

Bioluminescence Imaging Tumor Quantification Lymphoma Models D-Luciferin Firefly Luciferase Region Of Interest Total Flux Photon Flux
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