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JoVE Journal Bioengineering
Transporteigenschaften von Ibuprofen Encapsulated in Cyclodextrin Nanosponge Hydrogele
 
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Transporteigenschaften von Ibuprofen Encapsulated in Cyclodextrin Nanosponge Hydrogele: Ein Proton HR-MAS-NMR-Spektroskopie-Studie

Article DOI: 10.3791/53769-v • 10:10 min • August 15th, 2016
August 15th, 2016 •
*1, *1, 1, 1,2, 3, 4, 5, 1
1Department of Chemistry, Materials and Chemical Engineering "G. Natta", Politecnico di Milano, 2Università degli studi e-Campus, 3ICRM, CNR - Consiglio Nazionale delle Ricerche, 4Elettra Sincrotrone Trieste, 5Department of Chemistry, University of Torino
* These authors contributed equally

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Die Bewegungsregime in β-Cyclodextrin nanosponges Polymer-Netzwerk gekapselt Ibuprofen werden untersucht unter Verwendung von gepulstem Feld-Gradienten-Spin-Echo (PGSE) NMR-Technik. Synthese, Reinigung, Wirkstoffbeladung, die Umsetzung der NMR-Pulssequenz und Datenanalyse die mittlere quadratische Verschiebung des Medikaments an mehreren Beobachtungszeiten zu arbeiten, werden im Detail beschrieben.

Tags

Bioengineering Heft 114 Diffusion HR-MAS-NMR-Spektroskopie Biophysik Polymersynthese Cyclodextrin nanosponges Wirkstofffreisetzung Transportphänomene.
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