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Measuring the Stiffness of Ex Vivo Mouse Aortas Using Atomic Force Microscopy
 

Measuring the Stiffness of Ex Vivo Mouse Aortas Using Atomic Force Microscopy

Article DOI: 10.3791/54630-v • 10:35 min • October 19th, 2016
October 19th, 2016 •
1,2, 1,2, 3, 3, 1,2
1Program in Translational Biomechanics, Institute of Translational Medicine and Therapeutics, University of Pennsylvania, 2Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, 3Department of Physiology, University of Pennsylvania

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We present detailed protocols for isolation of aortas from mouse and measurement of their elastic modulus using atomic force microscopy.

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Atomic Force Microscopy Ex Vivo Mouse Aortas Elastic Modulus Measurement Vascular Biomechanics Cardiovascular Disease Aging AFM Procedures Mouse Aorta Isolation Soft Biological Samples Arteries Cells Accuracy Nanoscale Levels
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