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JoVE Journal Bioengineering
The Arteriovenous (AV) Loop in a Small Animal Model to Study Angiogenesis and Vascularized Tissue Engineering
 

The Arteriovenous (AV) Loop in a Small Animal Model to Study Angiogenesis and Vascularized Tissue Engineering

Article DOI: 10.3791/54676-v • 08:53 min • November 2nd, 2016
November 2nd, 2016 •
1, 1, 1, 1,2, 3, 1, 1
1Department of Plastic and Hand Surgery and Laboratory for Tissue Engineering and Regenerative Medicine, University Hospital of Erlangen, Friedrich-Alexander University of Erlangen-Nürnberg (FAU), 2Genetic Engineering and Biotechnology Institute for Postgraduate Studies, Baghdad University, 3Department of Plastic, Hand and Microsurgery, Sana Klinikum Hof GmbH

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We describe a microsurgical approach for the generation of an arteriovenous (AV) loop as a model for analyzing vascularization in vivo in an isolated and well-characterized environment. This model is not only useful for the investigation of angiogenesis, but is also optimally suited for engineering axially vascularized and transplantable tissues.

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Keywords: AV Loop Angiogenesis Vascularized Tissue Engineering Microsurgical Approach Axioli Vascular Access Tissue Engineering Angiostenosis Cancer Angiogenesis Microsurgery Micro Anastomosis Vascular Bundle Femoral Artery Femoral Vein
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