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Immunology and Infection

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JoVE Journal Immunology and Infection
Increased Recovery Time and Decreased LPS Administration to Study the Vagus Nerve Stimulation Mechanisms in Limited Inflammatory Responses
 

Increased Recovery Time and Decreased LPS Administration to Study the Vagus Nerve Stimulation Mechanisms in Limited Inflammatory Responses

Article DOI: 10.3791/54890-v • 06:43 min • March 29th, 2017
March 29th, 2017 •
1, 1, 1, 1
1Department of Medicine, Unit of Rheumatology, Center for Molecular Medicine (CMM), Karolinska Institute, Karolinska University Hospital

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Vagus nerve stimulation has proven to have a strong efficacy for decreasing peripheral inflammation. Here, we present a modified vagus nerve stimulation protocol that allows for further examinations of the cholinergic anti-inflammatory mechanisms in limited inflammatory responses.

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Keywords: Vagus Nerve Stimulation Inflammatory Response Cholinergic Anti-inflammatory Pathway Neuroimmunology Lipopolysaccharide (LPS) Mouse Surgery Anesthesia Sternocleidomastoid Muscle Carotid Artery
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