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JoVE Journal Bioengineering
Merging Ion Concentration Polarization between Juxtaposed Ion Exchange Membranes to Block the Propagation of the Polarization Zone
 

Merging Ion Concentration Polarization between Juxtaposed Ion Exchange Membranes to Block the Propagation of the Polarization Zone

Article DOI: 10.3791/55313-v • 08:06 min • February 23rd, 2017
February 23rd, 2017 •
1,2, 1,3, 1, 1, 1
1Center for BioMicrosystems, Korea Institute of Science and Technology, 2Department of Mechanical Engineering, Seoul National University, 3Department of Industrial Engineering, University of Illinois Urbana-Champaign

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The protocol for a novel ion concentration polarization (ICP) platform that can stop the propagation of the ICP zone, regardless of the operating conditions is described. This unique ability of the platform lies in the use of merging ion depletion and enrichment, which are two polarities of the ICP phenomenon.

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Ion Concentration Polarization Ion Exchange Membranes Bioagents Preconcentration Low Abundance Biomolecule Detection Sensor's Limit Of Detection ICP Zone Generation Specific Collision Photolithography Deep Reactive Ion Etching Silicon Masters Trichlorosilane Salinize Silicone Elastomer Base Curing Agent Uncured PDMS Vacuum Degassing Handheld Blower Curing PDMS Molds Rectangle Shape Cation-selective Membrane
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