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JoVE Journal Developmental Biology
A Novel Use of Three-dimensional High-frequency Ultrasonography for Early Pregnancy Characterization in the Mouse
 

A Novel Use of Three-dimensional High-frequency Ultrasonography for Early Pregnancy Characterization in the Mouse

Article DOI: 10.3791/56207-v • 07:04 min • October 24th, 2017
October 24th, 2017 •
1,4, 2, 2, 1, 1, *3, *4
1Devision of Repreoductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Baylor College of Medicine, 2Mouse Phenotyping Core, Baylor College of Medicine, 3Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, 4Department of Molecular and Cellular Biology, Baylor College of Medicine
* These authors contributed equally

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Resumo
Automatic Translation

Mice are widely used to study gestational biology. However, pregnancy termination is required for such studies which precludes longitudinal investigations and necessitates the use of large numbers of animals. Therefore, we describe a non-invasive technique of high-frequency ultrasonography for early detection and monitoring of post-implantation events in the pregnant mouse.

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Keywords: Three-dimensional High-frequency Ultrasonography Early Pregnancy Mouse Murine Reproductive Biology In Vivo Longitudinal Data 3-D Motor Stage Ultrasound Probe Bladder Pregnant Uterus 2-D Imaging Pregnancy Site Kidney Spleen Liver Uterine Horn Implantation Site Decidualization Reaction
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