Waiting
Processando Login

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Medicine / Development of Recombinant Proteins to Treat…
JoVE Journal
Medicine

É necessário ter uma assinatura JoVE para assistir este Faça login ou comece sua avaliação gratuita.

JoVE Journal Medicine
Development of Recombinant Proteins to Treat Chronic Pain
 

Development of Recombinant Proteins to Treat Chronic Pain

Article DOI: 10.3791/57071-v • 10:37 min • April 11th, 2018
April 11th, 2018 •
1, 2, 1, 1, 1, 1,3
1Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht University, 2Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University, 3Laboratory of Neuroimmunology and Developmental Origins of Disease, University Medical Center Utrecht, Utrecht University

Capítulos

Resumo
Automatic Translation

In this paper we provide details for the methods of production and quality control of an IL4-10 recombinant fusion protein. We also show how to test the effectiveness of this protein to resolve pain in a mouse model of inflammatory pain.

Tags

Recombinant Proteins Chronic Pain Treatment Fusion Protein Anti-inflammatory Cytokines IL4 IL10 Analgesic Properties Chronic Inflammatory Pain Models Biologics Development Quality Control Functional Activity Evaluation Therapeutic Potential Behavioral Tests Inflammatory Diseases HEK 293F Cells DNA Transfection Reagent Mixture Culture Supernatant
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter