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GPC3-targeting 双特异性抗体, GPC3-S-Fab, 具有强大的细胞毒性
 
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GPC3-targeting 双特异性抗体, GPC3-S-Fab, 具有强大的细胞毒性

Article DOI: 10.3791/57588-v • 11:13 min • July 12th, 2018
July 12th, 2018 •
1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2
1School of Pharmaceutical Sciences, Sun Yat-Sen University, 2Center for Cellular & Structural Biology, Sun Yat-Sen University

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在此, 我们提出了一种在大肠杆菌中产生双特异性抗体 GPC3-S-Fab 的协议.纯化 GPC3-S-Fab 对 GPC3 阳性肝癌细胞具有较强的细胞毒性作用。

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癌症研究 问题 137 双特异性抗体 抗体 单领域 VHH GPC3-S-Fab GPC3 肝癌
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