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JoVE Journal Developmental Biology
HUVEC Tube-formation Assay to Evaluate the Impact of Natural Products on Angiogenesis
 

HUVEC Tube-formation Assay to Evaluate the Impact of Natural Products on Angiogenesis

Article DOI: 10.3791/58591-v • 06:12 min • June 24th, 2019
June 24th, 2019 •
1, 1, 2, 1
1Laboratory of Cellular and Molecular Neuropathology, Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania "Luigi Vanvitelli", 2Department of Molecular Medicine and Biotechnologies, University of Naples "Federico II" Naples

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Here, we evaluate the effects of the water extract of Ruta graveolens on vessel network formation by using a tube formation assay on a gelled basement matrix.

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Keywords: HUVEC Tube Formation Assay Angiogenesis Natural Products RGWE MEK/ERK Pathway Endothelial Cells Cell Culture Transfection Extracellular Matrix
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