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JoVE Journal Neuroscience
Fluorescence Angiography for Evaluation of Aneurysm Perfusion and Parent Artery Patency in Rat and Rabbit Aneurysm Models
 

Fluorescence Angiography for Evaluation of Aneurysm Perfusion and Parent Artery Patency in Rat and Rabbit Aneurysm Models

Article DOI: 10.3791/59782-v • 04:08 min • July 24th, 2019
July 24th, 2019 •
1,2, 2, 1,2, 2, 2, 1,2, 1,2
1Department of Neurosurgery, Kantonsspital Aarau, 2Cerebrovascular Research Group, Department for BioMedical Research (DBMR), University of Bern

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We present a protocol to efficiently evaluate aneurysm perfusion and vessel patency of sidewall aneurysm in rats and rabbits, using fluorescein-based fluorescence video angiography (FVA). With a positive predictive value of 92.6%, it is a simple but very effective and economical method with no special equipment required.

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Keywords: Fluorescence Angiography Aneurysm Rat Rabbit Animal Model Blood Flow Visualization Surgery Fluorescein Sodium Camera Filter Macroscopic Analysis Parent Artery Patency
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