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Quantitative Approaches for Studying Cellular Structures and Organelle Morphology in Caenorhabditis elegans
 

Quantitative Approaches for Studying Cellular Structures and Organelle Morphology in Caenorhabditis elegans

Article DOI: 10.3791/59978-v • 08:47 min • July 5th, 2019
July 5th, 2019 •
*1, *1, *1, 1
1Neuroscience Program, Monash Biomedicine Discovery Institute and Department of Anatomy and Developmental Biology, Monash University, Melbourne VIC 3800, Australia.
* These authors contributed equally

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This study outlines quantitative measurements of synaptic size and localization, muscle morphology, and mitochondrial shape in C. elegans using freely available image processing tools. This approach allows future studies in C. elegans to quantitatively compare the extent of tissue and organelle structural changes as a result of genetic mutations.

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Keywords: Quantitative Analysis Cellular Structures Organelle Morphology Caenorhabditis Elegans Synapses Muscles Mitochondria Imaging Confocal Microscopy CellProfiler Image Analysis Gene Function Genetic Mutations Morphological Changes
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